KEGG   ENZYME: 1.2.1.44Help
Entry
EC 1.2.1.44                 Enzyme                                 

Name
cinnamoyl-CoA reductase;
feruloyl-CoA reductase;
cinnamoyl-coenzyme A reductase;
ferulyl-CoA reductase;
feruloyl coenzyme A reductase;
p-hydroxycinnamoyl coenzyme A reductase;
cinnamoyl-CoA:NADPH reductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)
Reaction(IUBMB)
cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+ [RN:R02506]
Reaction(KEGG)
Substrate
cinnamaldehyde [CPD:C00903];
CoA [CPD:C00010];
NADP+ [CPD:C00006]
Product
cinnamoyl-CoA [CPD:C00540];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Acts also on a number of substituted cinnamoyl esters of coenzyme A.
History
EC 1.2.1.44 created 1978
Pathway
ec00940  Phenylpropanoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09753  cinnamoyl-CoA reductase
Genes
RSS: 109442077
ATH: AT1G15950(CCR1) AT1G80820(CCR2)
ALY: ARALYDRAFT_351538 ARALYDRAFT_471794
CRB: 17894897 17897690
CSAT: 104703349 104714287 104740281 104752432 104755910 104774803
EUS: EUTSA_v10008111mg EUTSA_v10018849mg
BRP: 103832452(CCR2) 103842871 103853214(CCR2) 103872395
BNA: 106346798 106354822 106367088 106381558 106396237 106414831 106429710 106430708
BOE: 106295555 106296937 106311455 106327709
THJ: 104812427 104813587 104826414
CPAP: 110824762
TCC: 18595421
GRA: 105768894
EGR: 104423225
LJA: Lj0g3v0120879.1(Lj0g3v0120879.1) Lj3g3v0013390.1(Lj3g3v0013390.1) Lj3g3v2128240.1(Lj3g3v2128240.1) Lj3g3v2148260.1(Lj3g3v2148260.1)
FVE: 101302179
RCU: 8259741
JCU: 105630319
VVI: 100251623
SLY: 100125904(CCR1) 778359(CCR2)
LSV: 111892196
CCAV: 112509602
BVG: 104904880
SOE: 110805090
DOSA: Os01t0283600-00(Os01g0283600) Os01t0283700-01(Os01g0283700) Os02t0180700-01(Os02g0180700) Os02t0808800-01(Os02g0808800) Os02t0811400-00(Os02g0811400) Os02t0811600-00(Os02g0811600) Os02t0811800-01(Os02g0811800) Os02t0812000-01(Os02g0812000) Os08t0277200-01(Os08g0277200) Os08t0441500-01(Os08g0441500) Os09t0127300-01(Os09g0127300) Os09t0262000-00(Os09g0262000) Os09t0419200-01(Os09g0419200)
ATS: 109745831(LOC109745831) 109754250(LOC109754250) 109760091(LOC109760091) 109760092(LOC109760092) 109760607(LOC109760607) 109761766(LOC109761766) 109761768(LOC109761768) 109761769(LOC109761769) 109768974(LOC109768974) 109768977(LOC109768977) 109774003(LOC109774003) 109780729(LOC109780729) 109780731(LOC109780731) 109781309(LOC109781309)
DCT: 110093087
ATR: 18447024
 » show all
Taxonomy
Reference
1  [PMID:236926]
  Authors
Gross GG, Kreiten W.
  Title
Reduction of coenzyme A thioesters of cinnamic acids with an enzyme preparation from lignifying tissue of Forsythia.
  Journal
FEBS Lett 54:259-62 (1975)
DOI:10.1016/0014-5793(75)80087-1
Reference
2  [PMID:6365550]
  Authors
Sarni F, Grand C, Boudet AM.
  Title
Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana).
  Journal
Eur J Biochem 139:259-65 (1984)
DOI:10.1111/j.1432-1033.1984.tb08002.x
Reference
3  [PMID:7454]
  Authors
Wengenmayer H, Ebel J, Grisebach H.
  Title
Enzymic synthesis of lignin precursors. Purification and properties of a cinnamoyl-CoA: NADPH reductase from cell suspension cultures of soybean (Glycinemax).
  Journal
Eur J Biochem 65:529-36 (1976)
DOI:10.1111/j.1432-1033.1976.tb10370.x
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.44
IUBMB Enzyme Nomenclature: 1.2.1.44
ExPASy - ENZYME nomenclature database: 1.2.1.44
BRENDA, the Enzyme Database: 1.2.1.44
CAS: 59929-39-4

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