KEGG   ENZYME: 1.2.1.54Help
Entry
EC 1.2.1.54                 Enzyme                                 

Name
gamma-guanidinobutyraldehyde dehydrogenase;
alpha-guanidinobutyraldehyde dehydrogenase;
4-guanidinobutyraldehyde dehydrogenase;
GBAL dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4-guanidinobutanal:NAD+ 1-oxidoreductase
Reaction(IUBMB)
4-guanidinobutanal + NAD+ + H2O = 4-guanidinobutanoate + NADH + 2 H+ [RN:R03177]
Reaction(KEGG)
Substrate
4-guanidinobutanal [CPD:C02647];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-guanidinobutanoate [CPD:C01035];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the degradation of arginine in Pseudomonas putida (cf. EC 1.2.1.19 aminobutyraldehyde dehydrogenase).
History
EC 1.2.1.54 created 1989
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K12254  4-guanidinobutyraldehyde dehydrogenase / NAD-dependent aldehyde dehydrogenase
Genes
SLQ: M495_12010
XBA: C7S18_09045
PAE: PA5312
PAEV: N297_5492
PAEI: N296_5492
PAU: PA14_70140(aldH)
PAP: PSPA7_6087
PAG: PLES_57071
PAF: PAM18_5432
PNC: NCGM2_6076(aldH)
PAEB: NCGM1900_6154(aldH)
PAEP: PA1S_28715
PAEM: U769_29220
PAEL: T223_29175
PAEG: AI22_05275
PAEC: M802_5490
PAEO: M801_5357
PMY: Pmen_0237
PMK: MDS_0290
PPSE: BN5_0159
PCQ: PcP3B5_54750(puuC_3) PcP3B5_60480(puuC_4)
PPU: PP_5278(kauB)
PPF: Pput_5188
PPI: YSA_04677
PPX: T1E_2789
PPUH: B479_26140
PPUT: L483_31550
PPUN: PP4_53430
PSB: Psyr_0227
PSYR: N018_00480
PFL: PFL_6046
PPRC: PFLCHA0_c24080(puuC1) PFLCHA0_c60050(puuC4)
PFO: Pfl01_5534(aldH)
PFS: PFLU_5976(aldH)
PFB: VO64_2867
PEN: PSEEN5424(aldH)
PSA: PST_0046
PSTT: CH92_21230
PKC: PKB_5073(puuc3) PKB_5650(puuc5)
PSEC: CCOS191_5174(puuC3)
PANR: A7J50_5711
PSET: THL1_5607
AVN: Avin_48030(aldH)
AVL: AvCA_48030(aldH)
AVD: AvCA6_48030(aldH)
ACX: Achr_37390(aldH)
SAGA: M5M_11425
RFO: REIFOR_00600(puuC)
AVR: B565_3831
AMED: B224_5460
ASR: WL1483_1298(puuC)
ACAV: VI35_20215
OCE: GU3_00195
BMK: DM80_3359
PLG: NCTC10937_00050(puuC_1)
HYF: DTO96_100783(puuC)
JAG: GJA_494
MEH: M301_1070
TXI: TH3_10790
SMAL: SMALA_7627
 » show all
Taxonomy
Reference
1
  Authors
Yorifuji, T., Koike, K., Sakurai, T. and Yokoyama, K.
  Title
4-Aminobutyraldehyde and 4-guanidinobutyraldehyde dehydrogenases for arginine degradation in Pseudomonas putida.
  Journal
Agric Biol Chem 50:2009-2016 (1986)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.54
IUBMB Enzyme Nomenclature: 1.2.1.54
ExPASy - ENZYME nomenclature database: 1.2.1.54
BRENDA, the Enzyme Database: 1.2.1.54
CAS: 56831-75-5

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