KEGG   ENZYME: 1.2.1.82Help
Entry
EC 1.2.1.82                 Enzyme                                 

Name
beta-apo-4'-carotenal oxygenase;
beta-apo-4'-carotenal dehydrogenase;
YLO-1;
carD (gene name)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4'-apo-beta,psi-carotenal:NAD+ oxidoreductase
Reaction(IUBMB)
4'-apo-beta,psi-caroten-4'-al + NAD+ + H2O = neurosporaxanthin + NADH + 2 H+ [RN:R09783]
Reaction(KEGG)
Substrate
4'-apo-beta,psi-caroten-4'-al [CPD:C19892];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
neurosporaxanthin [CPD:C08607];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Neurosporaxanthin is responsible for the orange color of of Neurospora.
History
EC 1.2.1.82 created 2011
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
Orthology
K17819  beta-apo-4'-carotenal oxygenase
Genes
NCR: NCU04013(ylo-1)
NTE: NEUTE1DRAFT140784(NEUTE1DRAFT_140784)
SMP: SMAC_06187
PAN: PODANSg936
TTT: THITE_2110821
MTM: MYCTH_2307429
CTHR: CTHT_0045070
MGR: MGG_07270
TMN: UCRPA7_4168
SSCK: SPSK_05142
MAW: MAC_03864
MAJ: MAA_02951
CMT: CCM_09155
MBE: MBM_07141
ANI: AN5644.2
ANG: ANI_1_1254014(An01g09260)
ABE: ARB_07806
TVE: TRV_07386
PTE: PTT_13172
 » show all
Taxonomy
Reference
1  [PMID:18627463]
  Authors
Estrada AF, Youssar L, Scherzinger D, Al-Babili S, Avalos J
  Title
The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway.
  Journal
Mol Microbiol 69:1207-20 (2008)
DOI:10.1111/j.1365-2958.2008.06349.x
  Sequence
[ncr:NCU04013]
Reference
2  [PMID:21749649]
  Authors
Diaz-Sanchez V, Estrada AF, Trautmann D, Al-Babili S, Avalos J
  Title
The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi.
  Journal
FEBS J 278:3164-76 (2011)
DOI:10.1111/j.1742-4658.2011.08242.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.82
IUBMB Enzyme Nomenclature: 1.2.1.82
ExPASy - ENZYME nomenclature database: 1.2.1.82
BRENDA, the Enzyme Database: 1.2.1.82

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