KEGG   ENZYME: 1.20.2.1Help
Entry
EC 1.20.2.1                 Enzyme                                 

Name
arsenate reductase (cytochrome c);
arsenite oxidase (ambiguous)
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With a cytochrome as acceptor
BRITE hierarchy
Sysname
arsenite:cytochrome c oxidoreductase
Reaction(IUBMB)
arsenite + H2O + 2 oxidized cytochrome c = arsenate + 2 reduced cytochrome c + 2 H+ [RN:R09787]
Reaction(KEGG)
Substrate
arsenite [CPD:C06697];
H2O [CPD:C00001];
oxidized cytochrome c
Product
arsenate [CPD:C11215];
reduced cytochrome c [CPD:C00126];
H+ [CPD:C00080]
Comment
A molybdoprotein containing iron-sulfur clusters. Isolated from alpha-proteobacteria. Unlike EC 1.20.9.1, arsenate reductase (azurin), it does not use azurin as acceptor.
History
EC 1.20.2.1 created 2011
Orthology
K08355  arsenite oxidase small subunit
K08356  arsenite oxidase large subunit
Genes
VSP: VS_II0658 VS_II0659
VTA: A0943 A0944 B1225 B1226
MBS: MRBBS_1242(aoxB) MRBBS_1243(aoxA)
MPQ: ABA45_06345
MVS: MVIS_1833(aoxA)
MYA: MORIYA_1165 MORIYA_1166
HSI: BOX17_13460 BOX17_13465
RSL: RPSI07_mp0919(aoxA) RPSI07_mp0920(aoxB)
CUH: BJN34_21510 BJN34_21515
CBW: RR42_s1794 RR42_s1795
BMJ: BMULJ_05810(asoA) BMULJ_05811(asoB) BMULJ_05832(asoB) BMULJ_05833(asoA)
HAR: HEAR0478(aoxB) HEAR0479(aoxA)
THI: THI_3162(aoxB) THI_3163(aoxA)
SMUL: SMUL_3119(aioB) SMUL_3120(aioA)
AMIH: CO731_03145(aioB) CO731_03146(aioA)
RHT: NT26_p10029(aioB) NT26_p10030(aioA)
MSC: BN69_1400(aoxB) BN69_1401
RLI: RLO149_c022030(aoxA) RLO149_c022040(aoxB)
PMW: B2K_08810
TSC: TSC_c14680(aoxB) TSC_c14700(aoxA)
NDE: NIDE3704(aoxA) NIDE3705(aoxB)
 » show all
Taxonomy
Reference
1  [PMID:15178476]
  Authors
vanden Hoven RN, Santini JM
  Title
Arsenite oxidation by the heterotroph Hydrogenophaga sp. str. NT-14: the arsenite oxidase and its physiological electron acceptor.
  Journal
Biochim Biophys Acta 1656:148-55 (2004)
DOI:10.1016/j.bbabio.2004.03.001
Reference
2  [PMID:17306216]
  Authors
Santini JM, Kappler U, Ward SA, Honeychurch MJ, vanden Hoven RN, Bernhardt PV
  Title
The NT-26 cytochrome c552 and its role in arsenite oxidation.
  Journal
Biochim Biophys Acta 1767:189-96 (2007)
DOI:10.1016/j.bbabio.2007.01.009
Reference
3  [PMID:19525272]
  Authors
Branco R, Francisco R, Chung AP, Morais PV
  Title
Identification of an aox system that requires cytochrome c in the highly arsenic-resistant bacterium Ochrobactrum tritici SCII24.
  Journal
Appl Environ Microbiol 75:5141-7 (2009)
DOI:10.1128/AEM.02798-08
  Sequence
Reference
4  [PMID:20421652]
  Authors
Lieutaud A, van Lis R, Duval S, Capowiez L, Muller D, Lebrun R, Lignon S, Fardeau ML, Lett MC, Nitschke W, Schoepp-Cothenet B
  Title
Arsenite oxidase from Ralstonia sp. 22: characterization of the enzyme and its interaction with soluble cytochromes.
  Journal
J Biol Chem 285:20433-41 (2010)
DOI:10.1074/jbc.M110.113761
Other DBs
ExplorEnz - The Enzyme Database: 1.20.2.1
IUBMB Enzyme Nomenclature: 1.20.2.1
ExPASy - ENZYME nomenclature database: 1.20.2.1
BRENDA, the Enzyme Database: 1.20.2.1

DBGET integrated database retrieval system