KEGG   ENZYME: 1.20.4.3Help
Entry
EC 1.20.4.3                 Enzyme                                 

Name
mycoredoxin;
Mrx1;
MrxI
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With disulfide as acceptor
BRITE hierarchy
Sysname
arseno-mycothiol:mycoredoxin oxidoreductase
Reaction(IUBMB)
arseno-mycothiol + mycoredoxin = arsenite + mycothiol-mycoredoxin disulfide
Substrate
arseno-mycothiol;
mycoredoxin
Product
arsenite [CPD:C06697];
mycothiol-mycoredoxin disulfide
Comment
Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate. The substrate arseno-mycothiol is formed by EC 2.8.4.2 (arsenate:mycothiol transferase). A second mycothiol recycles mycoredoxin and forms mycothione.
History
EC 1.20.4.3 created 2010
Orthology
K18917  mycoredoxin
Genes
XBA: C7S18_10660
DTO: TOL2_C34390
MRM: A7982_05590
SSAN: NX02_p0320
SKR: BRX40_22330
MTU: Rv3198A
MTV: RVBD_3198A
MTC: MT3292
MRA: MRA_3235
MTF: TBFG_13221
MTUR: CFBS_3383
MTD: UDA_3198A
MTUC: J113_22285
MTUE: J114_17120
MTUH: I917_22450
MTUL: TBHG_03129
MTUT: HKBT1_3370
MTUU: HKBT2_3377
MBB: BCG_3223
MBT: JTY_3218
MBX: BCGT_3063
MAF: MAF_32060
MMIC: RN08_3528
MPA: MAP_3298
MAO: MAP4_0487
MAVI: RC58_02350
MAVU: RE97_02355
MAV: MAV_4144
MAVD: NF84_18985
MAVR: LA63_19185
MAVA: LA64_19175
MIT: OCO_40040
MIA: OCU_39950
MID: MIP_06036
MYO: OEM_40320
MIR: OCQ_41140
MLP: MLM_3305
MUL: MUL_2513
MMC: Mmcs_1408
MKM: Mkms_1426
MJL: Mjls_1462
MMI: MMAR_1363
MMM: W7S_19955
MHAD: B586_17065
MVA: Mvan_1806
MGI: Mflv_4661
MVQ: MYVA_1556
MAB: MAB_3512
MABB: MASS_3541
MABO: NF82_17600
MCHE: BB28_17980
MSTE: MSTE_03668
ASD: AS9A_3745
CGL: NCgl0808(Cgl0842)
CGB: cg0964
CGU: WA5_0808
CGT: cgR_0957
CGM: cgp_0964(mrx1)
CGJ: AR0_04770
CEF: CE0917
CDI: DIP0823
COP: Cp31_0637
CPSE: CPTA_01181
CPSU: CPTB_00351
CPSF: CPTC_01172
CVA: CVAR_0650
CTER: A606_02885
COA: DR71_1547
CSP: WM42_0573
CPHO: CPHO_09105
CGV: CGLAU_03615(mrx1)
CAQU: CAQU_03715
CAMG: CAMM_09560
NFA: NFA_45340
RER: RER_22230
REY: O5Y_10635
ROP: ROP_64420
REQ: REQ_32710(mrx)
RHB: NY08_1614
RRT: 4535765_03290(mrx_2)
GBR: Gbro_3497
GOR: KTR9_3525
TPR: Tpau_3048
SRT: Srot_2147
SCO: SCO5187(2SC3B6.11c)
SGR: SGR_2338
SGB: WQO_23815
SCT: SCAT_4050
SBH: SBI_04039
SHY: SHJG_6294
SVE: SVEN_4839
SALB: XNR_1616
SALS: SLNWT_2113
SFI: SFUL_4998
SALU: DC74_5336
SALL: SAZ_28280
STRE: GZL_03520
SLD: T261_2863
STRM: M444_22730
SPRI: SPRI_2688
SLE: sle_25550(sle_25550)
STRD: NI25_13240
SLAU: SLA_5021
SALJ: SMD11_2362
SFK: KY5_5307c
KSK: KSE_48950
CMI: CMM_2111
CMS: CMS1110
CMC: CMN_02076
ART: Arth_2324
ARM: ART_1003
AAU: AAur_2316
ACH: Achl_2050
BCV: Bcav_2898
JDE: Jden_0714
XCE: Xcel_0785
IDO: I598_1426
CFL: Cfla_2470
CFI: Celf_1170
MPH: MLP_31620
NCA: Noca_1515
KFL: Kfla_5338
PSIM: KR76_09295
TFU: Tfu_0529
NDA: Ndas_3808
TCU: Tcur_3744
SRO: Sros_8361
FAL: FRAAL6039
ACE: Acel_1772
GOB: Gobs_4233
MMAR: MODMU_4631
KRA: Krad_1178
PDX: Psed_1113
PSEA: WY02_21700
PSEE: FRP1_21490
PSEH: XF36_19845
KAL: KALB_8805
SAQ: Sare_4121
MIL: ML5_3002
ASE: ACPL_7612
ACTN: L083_7266
AFS: AFR_38360
ACTS: ACWT_7482
SNA: Snas_1785
TBI: Tbis_2967
DFO: Dform_01178(mrx1) Dform_01386(mrx1)
DGE: Dgeo_1508
DDR: Deide_06390(nrdH)
DGO: DGo_CA2073(grxA)
 » show all
Taxonomy
Reference
1  [PMID:19286650]
  Authors
Ordonez E, Van Belle K, Roos G, De Galan S, Letek M, Gil JA, Wyns L, Mateos LM, Messens J
  Title
Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange.
  Journal
J Biol Chem 284:15107-16 (2009)
DOI:10.1074/jbc.M900877200
  Sequence
[cgl:NCgl0808]
Other DBs
ExplorEnz - The Enzyme Database: 1.20.4.3
IUBMB Enzyme Nomenclature: 1.20.4.3
ExPASy - ENZYME nomenclature database: 1.20.4.3
BRENDA, the Enzyme Database: 1.20.4.3

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