KEGG   ENZYME: 1.3.1.13Help
Entry
EC 1.3.1.13                 Enzyme                                 

Name
prephenate dehydrogenase (NADP+);
prephenate dehydrogenase;
prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase;
prephenate dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
prephenate:NADP+ oxidoreductase (decarboxylating)
Reaction(IUBMB)
prephenate + NADP+ = 4-hydroxyphenylpyruvate + CO2 + NADPH [RN:R01730]
Reaction(KEGG)
Substrate
prephenate [CPD:C00254];
NADP+ [CPD:C00006]
Product
4-hydroxyphenylpyruvate [CPD:C01179];
CO2 [CPD:C00011];
NADPH [CPD:C00005]
History
EC 1.3.1.13 created 1972
Pathway
ec00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01130  Biosynthesis of antibiotics
Orthology
K00211  prephenate dehydrogenase (NADP+)
Genes
SCE: YBR166C(TYR1)
AGO: AGOS_AGR219W
ERC: Ecym_7090
KLA: KLLA0_E24729g
KMX: KLMA_10819(TYR1)
LTH: KLTH0E13794g
VPO: Kpol_1048p32
ZRO: ZYRO0A10384g
CGR: CAGL0M06017g
NCS: NCAS_0B01830(NCAS0B01830)
NDI: NDAI_0C05850(NDAI0C05850)
TPF: TPHA_0I01630(TPHA0I01630)
TBL: TBLA_0E04010(TBLA0E04010)
TDL: TDEL_0A05400(TDEL0A05400)
KAF: KAFR_0G02120(KAFR0G02120)
PIC: PICST_52223(TYR1)
CAL: CAALFM_C401880WA(TYR1)
CAUR: QG37_06333
SLB: AWJ20_4481(TYR1)
NCR: NCU00468
NTE: NEUTE1DRAFT63778(NEUTE1DRAFT_63778)
MGR: MGG_05276
SSCK: SPSK_07157
MAW: MAC_01666
MAJ: MAA_02500
CMT: CCM_09467
BFU: BCIN_03g06980(Bctyr1)
MBE: MBM_07073
ANI: AN5959.2
ANG: ANI_1_840024(An02g06120)
ABE: ARB_05782
TVE: TRV_04459
PTE: PTT_08159
SPO: SPCC1494.04c(tyr1)
CNE: CNK03330
CNB: CNBK0170
ABP: AGABI1DRAFT122388(AGABI1DRAFT_122388)
ABV: AGABI2DRAFT226049(AGABI2DRAFT_226049)
MUC: MuYL_4319
MGOT: MgSA37_01016(tyrA)
LBY: Lbys_1216
 » show all
Taxonomy
Reference
1  [PMID:4379953]
  Authors
Gamborg OL, Keeley FW.
  Title
Aromatic metabolism in plants. I. A study of the prephenate dehydrogenase from bean plants.
  Journal
Biochim Biophys Acta 115:65-72 (1966)
DOI:10.1016/0304-4165(66)90049-3
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.13
IUBMB Enzyme Nomenclature: 1.3.1.13
ExPASy - ENZYME nomenclature database: 1.3.1.13
BRENDA, the Enzyme Database: 1.3.1.13
CAS: 37251-11-9

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