KEGG   ENZYME: 1.3.1.64Help
Entry
EC 1.3.1.64                 Enzyme                                 

Name
phthalate 4,5-cis-dihydrodiol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase
Reaction(IUBMB)
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + NADH + H+ [RN:R05275]
Reaction(KEGG)
Substrate
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate [CPD:C04783];
NAD+ [CPD:C00003]
Product
4,5-dihydroxyphthalate [CPD:C03233];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the phthalate degradation pathway in bacteria.
History
EC 1.3.1.64 created 2000
Pathway
ec00624  Polycyclic aromatic hydrocarbon degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18067  phthalate 4,5-cis-dihydrodiol dehydrogenase
Genes
HAM: HALO0376
RPF: Rpic12D_2780 Rpic12D_4959
CNC: CNE_2c21270(pht2)
BVI: Bcep1808_4272
BMU: Bmul_4806
BMK: DM80_4021
BYI: BYI23_B001660 BYI23_D008170
BUO: BRPE64_DCDS03570 BRPE64_DCDS07100
BUE: BRPE67_BCDS04050
BPT: Bpet0249
BHZ: ACR54_04436(pht4)
POL: Bpro_1908
PNA: Pnap_4623
VEI: Veis_2924
CTES: O987_21845
CID: P73_2965
 » show all
Taxonomy
Reference
1  [PMID:3805038]
  Authors
Batie CJ, LaHaie E, Ballou DP.
  Title
Purification and characterization of phthalate oxygenase and phthalate oxygenase reductase from Pseudomonas cepacia.
  Journal
J Biol Chem 262:1510-8 (1987)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.64
IUBMB Enzyme Nomenclature: 1.3.1.64
ExPASy - ENZYME nomenclature database: 1.3.1.64
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.64
BRENDA, the Enzyme Database: 1.3.1.64

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