KEGG   ENZYME: 1.3.1.64Help
Entry
EC 1.3.1.64                 Enzyme                                 

Name
phthalate 4,5-cis-dihydrodiol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase
Reaction(IUBMB)
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + NADH + H+ [RN:R05275]
Reaction(KEGG)
Substrate
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate [CPD:C04783];
NAD+ [CPD:C00003]
Product
4,5-dihydroxyphthalate [CPD:C03233];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the phthalate degradation pathway in bacteria.
History
EC 1.3.1.64 created 2000
Pathway
ec00624  Polycyclic aromatic hydrocarbon degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18067  phthalate 4,5-cis-dihydrodiol dehydrogenase
Genes
HAM: HALO0376
RPF: Rpic12D_2780 Rpic12D_4959
CNC: CNE_2c21270(pht2)
BVI: Bcep1808_4272
BMU: Bmul_4806
BMJ: BMULJ_03711(ophB)
BMK: DM80_4021
BYI: BYI23_B001660 BYI23_D008170
BUO: BRPE64_DCDS03570 BRPE64_DCDS07100
BUE: BRPE67_BCDS04050 BRPE67_DCDS10090
BFN: OI25_3031
BCAI: K788_0000442
PHS: C2L64_49420
BPT: Bpet0249
BHZ: ACR54_04436(pht4)
BBRO: BAU06_03765
BFZ: BAU07_15850
BPDZ: BBN53_00970
BOH: AKI39_21315
PIG: EGT29_25715
RHY: RD110_25730
POL: Bpro_1908
PNA: Pnap_4623
POS: DT070_20435
ACID: CBP33_05515
ACIP: CBP36_05965 CBP36_20390
ACIN: CBP34_05350
ACIS: CBP35_12980
VEI: Veis_2924
DEL: DelCs14_1659
CTT: CtCNB1_1487
CTES: O987_21845
OTK: C6570_10600
LIM: L103DPR2_01699(pht4_1) L103DPR2_02575(pht4_2)
HYR: BSY239_3462
MASW: AM586_27435 AM586_27600 AM586_27665
ABAW: D5400_03690 D5400_20245
BVV: BHK69_01750
BOI: BLM15_16150
RHZ: RHPLAN_09750 RHPLAN_11140
MMED: Mame_05094(pht4)
PSIN: CAK95_02255 CAK95_05905
CID: P73_2965
CEH: CEW89_13895
TPRO: Ga0080559_TMP5106
PABY: Ga0080574_TMP2100
RID: RIdsm_00903(pht4)
NOR: FA702_15520
SPHJ: BSL82_13975
SPHR: BSY17_4183
SHYD: CJD35_19415 CJD35_19640
CNA: AB433_10230
POT: E2E27_18195
MYE: AB431_15435
 » show all
Taxonomy
Reference
1  [PMID:3805038]
  Authors
Batie CJ, LaHaie E, Ballou DP.
  Title
Purification and characterization of phthalate oxygenase and phthalate oxygenase reductase from Pseudomonas cepacia.
  Journal
J Biol Chem 262:1510-8 (1987)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.64
IUBMB Enzyme Nomenclature: 1.3.1.64
ExPASy - ENZYME nomenclature database: 1.3.1.64
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.64
BRENDA, the Enzyme Database: 1.3.1.64

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Pathway (7)   
   KEGG PATHWAY (6)   
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Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
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Gene (598)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (67)   
   KEGG MGENES (528)   
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Protein sequence (14)   
   UniProt (14)   
DNA sequence (28)   
   GenBank (14)   
   EMBL (14)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (655)   

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