| Entry |
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| Name |
phthalate 4,5-cis-dihydrodiol dehydrogenase
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| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase
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| Reaction(IUBMB) |
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + NADH + H+ [RN: R05275]
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| Reaction(KEGG) |
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| Substrate |
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate [CPD: C04783];
NAD+ [CPD: C00003]
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| Product |
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| Comment |
Involved in the phthalate degradation pathway in bacteria.
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| History |
EC 1.3.1.64 created 2000
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| Pathway |
| ec00624 | Polycyclic aromatic hydrocarbon degradation |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K18067 | phthalate 4,5-cis-dihydrodiol dehydrogenase |
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| Genes |
» show all
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| Reference |
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| Authors |
Batie CJ, LaHaie E, Ballou DP. |
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| Title |
Purification and characterization of phthalate oxygenase and phthalate oxygenase reductase from Pseudomonas cepacia. |
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| Journal |
J Biol Chem 262:1510-8 (1987) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.3.1.64 |
| ExPASy - ENZYME nomenclature database: | 1.3.1.64 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 1.3.1.64 |
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