KEGG   ENZYME: 1.3.1.73Help
Entry
EC 1.3.1.73                 Enzyme                                 

Name
1,2-dihydrovomilenine reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
17-O-acetylnorajmaline:NADP+ oxidoreductase
Reaction(IUBMB)
17-O-acetylnorajmaline + NADP+ = 1,2-dihydrovomilenine + NADPH + H+ [RN:R05879]
Reaction(KEGG)
Substrate
17-O-acetylnorajmaline [CPD:C11809];
NADP+ [CPD:C00006]
Product
1,2-dihydrovomilenine [CPD:C11808];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Forms part of the ajmaline biosynthesis pathway.
History
EC 1.3.1.73 created 2002
Pathway
ec00901  Indole alkaloid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Reference
1  [PMID:12391554]
  Authors
Gao S, von Schumann G, Stockigt J.
  Title
A newly-detected reductase from Rauvolfia closes a gap in the biosynthesis of the antiarrhythmic alkaloid ajmaline.
  Journal
Planta Med 68:906-11 (2002)
DOI:10.1055/s-2002-34935
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.73
IUBMB Enzyme Nomenclature: 1.3.1.73
ExPASy - ENZYME nomenclature database: 1.3.1.73
BRENDA, the Enzyme Database: 1.3.1.73

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