KEGG   ENZYME: 1.3.99.4Help
Entry
EC 1.3.99.4                 Enzyme                                 

Name
3-oxosteroid 1-dehydrogenase;
3-oxosteroid Delta1-dehydrogenase;
Delta1-dehydrogenase;
3-ketosteroid-1-en-dehydrogenase;
3-ketosteroid-Delta1-dehydrogenase;
1-ene-dehydrogenase;
3-oxosteroid:(2,6-dichlorphenolindophenol) Delta1-oxidoreductase;
4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase;
Delta1-steroid reductase;
3-oxosteroid:(acceptor) Delta1-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors
BRITE hierarchy
Sysname
3-oxosteroid:acceptor Delta1-oxidoreductase
Reaction(IUBMB)
a 3-oxosteroid + acceptor = a 3-oxo-Delta1-steroid + reduced acceptor [RN:R03748]
Reaction(KEGG)
Substrate
3-oxosteroid [CPD:C01876];
acceptor [CPD:C00028]
Product
3-oxo-Delta1-steroid [CPD:C02941];
reduced acceptor [CPD:C00030]
History
EC 1.3.99.4 created 1965
Pathway
ec00984  Steroid degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05898  3-oxosteroid 1-dehydrogenase
Genes
EBI: EbC_17210
PRE: PCA10_12340(kstD)
PPUT: L483_14095
PPUN: PP4_27200(kstD3)
PVR: PverR02_11670
PPUU: PputUW4_01674
PKC: PKB_4330
PFZ: AV641_10565
PLQ: AA042_20370
PPSY: AOC04_07865
PSET: THL1_1313
PSIL: PMA3_11570
SPL: Spea_2125
SHL: Shal_2097
PHA: PSHAa2133(tesH)
PTN: PTRA_a2586(kstD)
PNG: PNIG_a2780(kstD)
REH: H16_B0639(h16_B0639)
CNC: CNE_2c05840(kstD) CNE_BB1p03860(ksdD1) CNE_BB1p04140(kstD)
BCJ: BCAM1646
BCEN: DM39_6203
BCEO: I35_5506
BCT: GEM_4009
BCED: DM42_6312(kstD)
BCON: NL30_03955
BTEI: WS51_05855
BPSL: WS57_05850
BMEC: WJ16_26970
BFN: OI25_4615
BPE: BP3500
BPC: BPTD_3450
BPER: BN118_0892
BPET: B1917_3279
BPEU: Q425_6020
BPA: BPP0873
BPAR: BN117_3822
BBR: BB0967
CTES: O987_07760
PLA: Plav_1792
KVL: KVU_PA0184(kstD3)
SGI: SGRAN_3515(kstD)
SPHM: G432_17580
SSAN: NX02_07685
SPHB: EP837_02950(urdA) EP837_03338(kstD)
SPHT: K426_15965
SFLA: SPHFLASMR4Y_02381(kstD)
BLAS: BSY18_830
LSP: Bsph_0520
MTU: Rv3537(kstD)
MTV: RVBD_3537
MTC: MT3641
MRA: MRA_3576
MTUR: CFBS_3753
MTD: UDA_3537
MTUB: MT7199_3599(kstD)
MTUC: J113_24750
MTUE: J114_18915
MTUH: I917_24820
MTUL: TBHG_03477
MTUT: HKBT1_3738
MTUU: HKBT2_3747
MBO: BQ2027_MB3567(kstd)
MBB: BCG_3601
MBT: JTY_3602
MBX: BCGT_3403
MAF: MAF_35490
MMIC: RN08_3913
MCQ: BN44_110029(kstD)
MCV: BN43_90035(kstD)
MCX: BN42_90032(kstD)
MCZ: BN45_100032(kstD)
MPA: MAP_0530c
MAV: MAV_0624
MLP: MLM_0768
MUL: MUL_4098
MMC: Mmcs_4662
MKM: Mkms_4750
MJL: Mjls_5045
MMI: MMAR_5024
MHAD: B586_04625
MGI: Mflv_1519
MPHL: MPHLCCUG_00564(ksdD_1)
MVQ: MYVA_5132
MTHN: 4412656_02901(kstD_3) 4412656_04053(ksdD)
MAB: MAB_0622c
MABB: MASS_0592
MCHE: BB28_02980
MSTE: MSTE_00581
MTER: 4434518_03655(kstD)
ASD: AS9A_0923(kstD3)
CGT: cgR_2520
NFA: NFA_4630
NFR: ERS450000_03774(kstD_1)
RHA: RHA1_ro04532(kstD) RHA1_ro09040(kstD)
RER: RER_07370(kstD3) RER_29470 RER_51050(kstD1)
ROP: ROP_44470(kstD3)
RRT: 4535765_00579(kstD_1)
GBR: Gbro_0895
GPO: GPOL_c41290(kstD1) GPOL_c41370(kstD2)
GOR: KTR9_0802(kstD)
TPR: Tpau_3848
SDV: BN159_3882(kstD)
SALU: DC74_7450
SALL: SAZ_38455
STRM: M444_05900
SLX: SLAV_27450(kstD1) SLAV_33045(kstD2)
IDO: I598_0510(ksdD)
ACIJ: JS278_02361(ksdD)
NCA: Noca_2780
NDK: I601_0580(kstD_1) I601_3473(ksdD)
TCU: Tcur_3521
KAL: KALB_5140
AFS: AFR_27765
CAI: Caci_5094
CAU: Caur_0376
TRO: trd_1806
 » show all
Taxonomy
Reference
1  [PMID:13673006]
  Authors
LEVY HR, TALALAY P.
  Title
Bacterial oxidation of steroids. II. Studies on the enzymatic mechanism of ring A dehydrogenation.
  Journal
J Biol Chem 234:2014-21 (1959)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.99.4
IUBMB Enzyme Nomenclature: 1.3.99.4
ExPASy - ENZYME nomenclature database: 1.3.99.4
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.99.4
BRENDA, the Enzyme Database: 1.3.99.4
CAS: 9029-04-3

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