KEGG   ENZYME: 1.4.1.16Help
Entry
EC 1.4.1.16                 Enzyme                                 

Name
diaminopimelate dehydrogenase;
meso-alpha,epsilon-diaminopimelate dehydrogenase;
meso-diaminopimelate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)
Reaction(IUBMB)
meso-2,6-diaminoheptanedioate + H2O + NADP+ = L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+ [RN:R02755]
Reaction(KEGG)
Substrate
meso-2,6-diaminoheptanedioate [CPD:C00680];
H2O [CPD:C00001];
NADP+ [CPD:C00006]
Product
L-2-amino-6-oxoheptanedioate [CPD:C03871];
NH3 [CPD:C00014];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.4.1.16 created 1981
Pathway
ec00300  Lysine biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K03340  diaminopimelate dehydrogenase
Genes
LPV: HYN51_05185
PMR: PMI0150
PMIB: BB2000_0314
PVL: AOB99_03565
PVG: CRN77_00455
PSI: S70_05250
PSX: DR96_162
PSTA: BGK56_08125
PRG: RB151_034360(ddh)
PALA: CO695_09150
PHEI: NCTC12003_01013(ddh)
MMK: MU9_1099
LRI: NCTC12151_02519(ddh)
MBS: MRBBS_3827(ddh)
TGR: Tgr7_1592
GPB: HDN1F_28820(ddh)
BTRM: SAMEA390648702348(ddh)
PUT: PT7_3660
AFQ: AFA_14700
RFR: Rfer_1518
AJS: Ajs_2757
DAC: Daci_2479
CTES: O987_19680
HAR: HEAR2481(ddh)
OFO: BRW83_0212(ddh)
CCO: CCC13826_1251(ddh)
CGRA: CGRAC_1064(ddh)
CSPF: CSF_0917(ddh)
PCA: Pcar_2787
DDS: Ddes_1119
BACO: OXB_3226
AXL: AXY_06490(ddh)
LSP: Bsph_3035
PLV: ERIC2_c02960(ddh)
PRI: PRIO_3117(ddh)
SIV: SSIL_2217
THL: TEH_03760(ddh)
CRN: CAR_c12320(ddh)
CARC: NY10_629
CTC: CTC_02532
CBK: CLL_A3000
CBN: CbC4_2183
CBT: CLH_2749
CBV: U729_1583
CTH: Cthe_0922
HSC: HVS_16175(ddh)
CCE: Ccel_2533
CSS: Cst_c19600(ddh2)
CSD: Clst_1878
RUM: CK1_20790
BPB: bpr_I0298
BFI: CIY_14290
BHU: bhn_I0383
ROB: CK5_18050
RTO: RTO_26020
CPY: Cphy_2659
CSO: CLS_20310
BPRL: CL2_13780
HSD: SD1D_0623(ddh)
STH: STH1425
SWO: Swol_0940
DSY: DSY0242
DHD: Dhaf_0187
EHL: EHLA_0471
BPRS: CK3_21290
TAE: TepiRe1_0380(ddh) TepiRe1_2158(ddh)
PED: ING2D1G_0503(ddh)
CAD: Curi_c28460(ddh)
VPR: Vpar_0329
VRM: 44547418_00350(ddh)
SRI: SELR_03300(ddh)
AIN: Acin_0942
ACL: ACL_0763
CGL: NCgl2528(Cgl2617)
CGB: cg2900(ddh)
CGU: WA5_2528(Ddh)
CGT: cgR_2525
CGM: cgp_2900(ddh)
CGJ: AR0_12640
CEF: CE2498(ddh)
CUR: cu1936(ddh)
CUA: CU7111_1859(ddh)
COA: DR71_1201
CMQ: B840_10740(ddh)
CEI: CEPID_10565(ddh)
CTED: CTEST_11385(ddh)
CDX: CDES_11895(ddh)
ARM: ART_1975
AAI: AARI_01410(ddh)
TPYO: X956_00505
ELE: Elen_0753
AEQ: AEQU_0447
OTE: Oter_4154
AMU: Amuc_0581
AGL: PYTT_1914
EMI: Emin_1048
FSC: FSU_0395
BTH: BT_1979
BTHO: Btheta7330_01067(ddh)
BFR: BF3690
BVU: BVU_1659
BOA: Bovatus_02055(ddh)
BCEL: BcellWH2_01403(ddh)
PGI: PG_0806
PGN: PGN_0830
PCRE: NCTC12858_00444(ddh)
PBT: ING2E5B_1540(ddh)
PMUC: ING2E5A_1339(ddh)
PDI: BDI_3565
TFO: BFO_1811
PSAC: PSM36_2295(ddh)
PRU: PRU_2042
MYR: MYRA21_2854(ddh)
MPW: MPR_1710
NDE: NIDE3823
MHI: Mhar_0438
 » show all
Taxonomy
Reference
1  [PMID:10904]
  Authors
Misono H, Togawa H, Yamamoto T, Soda K.
  Title
Occurrence of meso-alpha, epsilon-diaminopimelate dehydrogenase in Bacillus sphaericus.
  Journal
Biochem Biophys Res Commun 72:89-93 (1976)
DOI:10.1016/0006-291X(76)90964-5
Reference
2  [PMID:762012]
  Authors
Misono H, Togawa H, Yamamoto T, Soda K.
  Title
Meso-alpha,epsilon-diaminopimelate D-dehydrogenase: distribution and the reaction product.
  Journal
J Bacteriol 137:22-7 (1979)
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.4.1.16
IUBMB Enzyme Nomenclature: 1.4.1.16
ExPASy - ENZYME nomenclature database: 1.4.1.16
BRENDA, the Enzyme Database: 1.4.1.16
CAS: 60894-21-5

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