KEGG   ENZYME: 1.5.8.1Help
Entry
EC 1.5.8.1                  Enzyme                                 

Name
dimethylamine dehydrogenase
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With a flavin or flavoprotein as acceptor
BRITE hierarchy
Sysname
dimethylamine:electron-transfer flavoprotein oxidoreductase
Reaction(IUBMB)
dimethylamine + H2O + electron-transfer flavoprotein = methylamine + formaldehyde + reduced electron-transfer flavoprotein [RN:R01588]
Reaction(KEGG)
Substrate
dimethylamine [CPD:C00543];
H2O [CPD:C00001];
electron-transfer flavoprotein [CPD:C04253]
Product
methylamine [CPD:C00218];
formaldehyde [CPD:C00067];
reduced electron-transfer flavoprotein [CPD:C04570]
Comment
Contains FAD and a [4Fe-4S] cluster.
History
EC 1.5.8.1 created 1999 as EC 1.5.99.10, transferred 2002 to EC 1.5.8.1
Pathway
ec00680  Methane metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K00317  dimethylamine/trimethylamine dehydrogenase
Genes
RHD: R2APBS1_0788
DJI: CH75_07125
DTX: ATSB10_15590
XBA: C7S18_14515
PRE: PCA10_47330
PFC: PflA506_4693(tmd)
POI: BOP93_22725
TSN: W908_00015
RSO: RSp0682
RSL: RPSI07_mp0583
RSN: RSPO_m01017(stcD)
RSE: F504_4539
BPH: Bphy_5960
PSPU: NA29_08505
CFU: CFU_2684
CPRA: CPter91_1920(tmd)
MEH: M301_1400
MEP: MPQ_2403
SME: SMa0257
SMI: BN406_04939(tmd)
SMER: DU99_24725
SMD: Smed_1285
OAN: Oant_3262
OAH: DR92_3227(hdh)
OCH: CES85_4558(tmd)
XAU: Xaut_0917
MCG: GL4_2663
RDE: RD1_4141(tmd)
RLI: RLO149_c003340(tmd)
PAMN: pAMV3p0110(dmd) pAMV3p0194(tmd)
OAT: OAN307_c42970(tmd)
OAR: OA238_c47830(tmd1) OA238_c47840(tmd2) OA238_c47850(tmd3)
OTM: OSB_15670(tmd)
RMM: ROSMUCSMR3_03636(tmd)
MVQ: MYVA_5919
TPR: Tpau_0381
NCA: Noca_0618
PSIM: KR76_16005
RCA: Rcas_1934
 » show all
Taxonomy
Reference
1  [PMID:7556160]
  Authors
Yang CC, Packman LC, Scrutton NS.
  Title
The primary structure of Hyphomicrobium X dimethylamine dehydrogenase. Relationship to trimethylamine dehydrogenase and implications for substrate recognition.
  Journal
Eur J Biochem 232:264-71 (1995)
DOI:10.1111/j.1432-1033.1995.tb20808.x
  Sequence
[hdn:Hden_0194]
Other DBs
ExplorEnz - The Enzyme Database: 1.5.8.1
IUBMB Enzyme Nomenclature: 1.5.8.1
ExPASy - ENZYME nomenclature database: 1.5.8.1
UM-BBD (Biocatalysis/Biodegradation Database): 1.5.8.1
BRENDA, the Enzyme Database: 1.5.8.1
CAS: 68247-64-3

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