KEGG ENZYME: 1.7.3.3

ENZYME: 1.7.3.3

Entry

EC 1.7.3.3                  Enzyme

Name

factor-independent urate hydroxylase;
uric acid oxidase;
uricase;
uricase II;
urate oxidase

Class

Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With oxygen as acceptor

Sysname

urate:oxygen oxidoreductase

Reaction(IUBMB)

urate + O2 + H2O = 5-hydroxyisourate + H2O2 [RN:R02106]

Reaction(KEGG)

R02106;
(other) R07981

Substrate

urate [CPD:C00366];
O2 [CPD:C00007];
H2O [CPD:C00001]

Product

5-hydroxyisourate [CPD:C11821];
H2O2 [CPD:C00027]

Comment

This enzyme was previously thought to be a copper protein, but it is now known that the enzymes from soy bean (Glycine max), the mould Aspergillus flavus and Bacillus subtilis contains no copper nor any other transition-metal ion. The 5-hydroxyisourate formed decomposes spontaneously to form allantoin and CO2, although there is an enzyme-catalysed pathway in which EC 3.5.2.17, hydroxyisourate hydrolase, catalyses the first step. The enzyme is different from EC 1.14.13.113 (FAD-dependent urate hydroxylase).

History

EC 1.7.3.3 created 1961, modified 2002, modified 2005, modified 2010

Pathway

ec00230

Purine metabolism

ec00232

Caffeine metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K00365

urate oxidase

K16838

urate oxidase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

Genes

NLE:

100597726

MCC:

714004

MCF:

102117077

MTHB:

126963640

MNI:

105482746

CSAB:

103224536

CATY:

105593567

PANU:

100998784

TGE:

112628445

MLEU:

105538069

RRO:

104677513

RBB:

108527687

TFN:

117092165

PTEH:

111540355

CANG:

105521857

CJC:

100397154

SBQ:

101040936

CIMI:

108283463

ANAN:

105710282

MMUR:

105861795

LCAT:

123635474

PCOQ:

105823900

OGA:

100956247

MMU:	22262(Uox)

MCAL:

110291256

MPAH:

110320533

RNO:	114768(Uox)

MCOC:

116094386

ANU:

117707839

ASYL:

127682574

MUN:

110555015

CGE:

100768251

MAUA:

101827959

PROB:

127229878

PLEU:

114698269

MORG:

121448318

MFOT:

126512381

AAMP:

119801296

NGI:

103728098

HGL:

101719675

CPOC:

100733081

CCAN:

109688705

DORD:

105987044

DSP:

122103685

DMER:

138817052

PLOP:

125354346

NCAR:

124975056

MMMA:

107158292

ITI:

101966455

OCU:

100009266

OPI:

101526796

TUP:

102500418

GVR:

103589597

CFA:	490189(UOX)

CLUD:

112640984

VVP:

112924412

VLG:

121487812

NPO:

129520277

AML:

100470134

UMR:

103662970

UAH:

113254484

UAR:

123794967

ELK:

111143395

LLV:

125098225

MPUF:

101691492

MNP:

132001962

MLK:

131810186

NVS:

122898753

ORO:

101366343

EJU:

114208481

ZCA:

113935935

MLX:

118019225

NSU:

110580448

LWW:

102731882

FCA:

101096750

PYU:

121027381

PCOO:

112848422

PBG:

122480700

PVIV:

125173919

LRUF:

124514465

LGF:

123598138

AJU:

106973351

PTG:

102971100

PPAD:

109246177

PUC:

125912460

PLEZ:

122227725

HHV:

120241661

BTA:	514113(UOX)

BOM:

102267915

BIU:

109556136

BBUB:

102411007

BBIS:

105003256

CHX:

102168228

OAS:

101109838

BTAX:

128045112

CSUM:

138073369

ODA:

120856945

CCAD:

122436770

MREE:

136149659

OVR:

110135920

MBEZ:

129540361

SSC:	397510(UOX)

CFR:

102505313

CBAI:

105075495

CDK:

105095038

VPC:

102527220

BACU:

103009966

BMUS:

118890940

LVE:

103070467

OOR:

101275718

LALB:

132515516

GMF:

115858383

DDP:

132433521

DLE:

111178377

PCAD:

102983042

PSIU:

116759011

PPHC:

136125741

NASI:

112415079

ECB:

100064919

EPZ:

103557286

EAI:

106824012

MYB:

102244414

MYD:

102751767

MMYO:

118676280

MLF:

102440467

MDT:

132230903

MYUM:

139001865

PKL:

118722346

EFUS:

103284273

MNA:

107543171

DRO:

112309394

SHON:

118997369

AJM:

119062885

PDIC:

114497513

PHAS:

123816544

MMF:

118626625

PPAM:

129065643

HAI:

109385433

RFQ:

117027787

PALE:

102878680

PGIG:

120583274

PVP:

105289066

RAY:

107511587

MJV:

108386581

TOD:

119235842

SARA:

101539405

SFUM:

130031920

SETR:

126005944

LAV:

100668450

TMU:

101357598

ETF:

101645372

DNM:

101420609

MDO:

100012925

SHR:

100917431

AFZ:

127563018

PCW:

110209927

TVP:

118846458

PBRV:

138166099

MLAO:

141512683

OAA:

100078972

TACU:

119927311

GGA:

101747367

PCOC:

116233357

MGP:

100551010

CJO:

107317543

TPAI:

128072671

LMUT:

125693050

NMEL:

110402305

APLA:

101797537

ACYG:

106033995

CATA:

118243432

AFUL:

116491890

TGU:

100189932

LSR:

110468816

SCAN:

103815159

PMOA:

120510834

OTC:

121345123

PRUF:

121362003

ATRC:

139594063

GFR:

102040716

FAB:

101806442

OMA:

130256092

PHI:

102109233

PMAJ:

107208239

CCAE:

111932859

CCW:

104695300

CBRC:

103612803

ACOE:

138113764

ETL:

114064914

ZAB:

102068609

ACHL:

103804863

SVG:

106857431

MMEA:

130578622

HRT:

120756556

SATI:

136365186

CCIC:

134046835

FPG:

101917753

CCRI:

104168242

NNT:

104408380

SHAB:

115612222

ACUN:

113482838

ACHC:

115349367

HALD:

104325205

HLE:

104841219

AGEN:

126041576

HHAR:

128147769

GCL:

127019105

CSTI:

104553163

LDI:

104341663

MNB:

103774213

DPUB:

104300110

PPUS:

135177894

AVIT:

104281460

BRHI:

104489179

EGZ:

104122902

NNI:

104015567

PCRI:

104028066

PCAO:

104045270 104049055

PADL:

103925216

AFOR:

103894871

FGA:

104083146

GSTE:

104262264

CBOY:

140654113

CLV:

102096622

CNIC:

136002144

MUI:

104545040

PGUU:

104459978

PLET:

104615236

EHS:

104506561

CMAC:

104487562

CUCA:

104055208

TEO:

104378013

BREG:

104641727

OHA:

104338833

ACAR:

104524358

CPEA:

104396832

CVF:

104286147

RTD:

128913520

CRID:

134519449

AAM:

106499688

AROW:

112961906

NPD:

112946255

TGT:

104565328

DNE:

112993126

SCAM:

104143000

ASN:

102373915

AMJ:	102571917(UOX)

CPOO:

109307346

GGN:

109305327

PSS:	102453497 102453977

CMY:	102932244 102932468

CCAY:

125641903 125641907

DCC:	119860117 119860449

CPIC:

101936730 101944737

TST:	117882030 117882031

CABI:

116835757 116835765

MRV:	120370462 120370465

ACS:

100552598

ASAO:

132774080

PVT:

110079741

SUND:

121930000

PBI:

103058911

PMUR:

107285242

CTIG:

120297891

PGUT:

117677350

PCAE:

139315053

APRI:

131195670

PTEX:

113435963

NSS:

113419174

VKO:

123024487

PMUA:

114598436

PRAF:

128415116

ZVI:

118089130

HCG:

128325089

GJA:

107117302

STOW:

125432806

EMC:

129330339

XLA:	108714977 399031(uox.L)

XTR:	496896(uox)

NPR:

108791380

RTEM:

120945980

ACAT:

141103734

BBUF:

120979288

BGAR:

122943160

DTC:

141048831

PWL:

138294197

MUO:

115471882

GSH:

117346928

DRE:	436604(uox)

SRX:

107742901

SANH:

107658581 107669002

SGH:

107560424

CCAR:

109098556

CAUA:

113054948

CGIB:

128022626

PTET:

122353934(uox)

LROH:

127172873(uox)

GRF:	141294127(uox)

OMC:	131549846(uox)

PPRM:

120464182(uox)

RKG:	130078095(uox)

MAMB:

125257006(uox)

CIDE:

127522431

CERY:

137021707(uox)

MASI:

127426448

TROS:

130571506(uox)

TDW:	130410577(uox)

MANU:

129427098(uox)

PDAB:

135719283(uox)

IPU:	100528126(uox)

IFU:	128614030(uox)

PHYP:

113529137

SMEO:

124391089(uox)

TFD:	113651623(uox)

TVC:	132853733(uox)

CGAR:

128542829(uox)

NGRA:

132899563(uox)

TRN:	134331142(uox)

AMEX:

103030682(uox)

CMAO:

118818950(uox)

EEE:

113581895

CHAR:

122130204(uox)

SPIL:

134101669(uox)

TRU:

101078943

TFS:	130528160(uox)

TNG:	GSTEN00022862G001

LCO:

104931943

NCC:

104941345

TBEN:

117495555(uox)

CGOB:

115006622

PGEO:

117445961(uox)

GACU:

117555221(uox)

EMAC:

134869667(uox)

ELY:	117253362(uox)

EFO:	125896147(uox)

PLEP:

121966164(uox)

SLUC:

116055423(uox)

ECRA:

117950664(uox)

ESP:

116695973

PFLV:

114561451

GAT:	120823961(uox)

PPUG:

119216288(uox)

AFB:	129094377(uox)

CLUM:

117729665(uox)

PSWI:

130193461(uox)

CANA:

137794689(uox)

CVE:	137870318(uox)

MSAM:

119900633(uox)

SCHU:

122877469(uox)

CUD:	121512608(uox)

SPUL:

138607870(uox)

LMIX:

132964617(uox)

ALAT:

119028391(uox)

ASTR:

137599486(uox)

MZE:

101475077

ONL:

100711225

OAU:	116333045(uox)

OLA:

101159660

OML:	112150775(uox)

CSAI:

133458482(uox)

XMA:

102230976

XCO:

114150834

XHE:	116725610 116727894

PRET:

103464157

PFOR:

103130861 103130884

PLAI:

106941472 106959866

PMEI:

106923626 106930008

GAF:	122838692(uox)

PPRL:

129371391(uox)

CVG:

107087215

CTUL:

119774617(uox)

GMU:	124873961(uox)

NFU:

107392713

KMR:	108234387(uox)

ALIM:

106511397

NWH:	119430624(uox)

AOCE:

111586381(uox)

EJA:	138198543(uox)

BFRE:

138618759(uox)

MCEP:

125008934(uox)

CSEM:

103392251

POV:

109625259

SSEN:

122780818(uox)

SSOE:

131465247(uox)

HHIP:

117759928(uox)

HSP:	118121341(uox)

PPLT:

128448246(uox)

SMAU:

118318253(uox)

LCF:	108881276(uox)

SDU:

111230334

SLAL:

111658501

XGL:	120790336(uox)

HCQ:

109522038

SSCV:

125969655(uox)

SBIA:

133504137(uox)

PEE:	133406414(uox)

PTAO:

133481441(uox)

BPEC:

110160092

ENY:	140353853(uox)

MALB:

109958355

BSPL:

114854463(uox)

SJO:	128361325(uox)

SSCO:

133984641(uox)

GMH:

115555417

SASA:

100136464

STRU:

115157933

OTW:	112217413(uox)

OMY:	110521955(uox)

OGO:	123994963(uox)

ONE:

115139545

OKI:

109866672

OKE:	118386772(uox)

OMM:	135557351(uox)

OCLA:

139406912

SALP:

111976044 112080518

SNH:	120054592(uox)

CCLU:

121533288(uox)

ELS:

105008143

OEP:	134011409(uox)

SFM:

108923494

PKI:

111860542

AANG:

118225826(uox)

AROT:

135253742(uox)

CCOG:

133126497(uox)

LOC:

102689735

PSPA:

121331102(uox)

ARUT:

117411523(uox)

PSEX:

120515285(uox)

LCM:

102360643

CMK:	103174706(uox)

RTP:	109916159(uox)

CPLA:

122554114(uox)

HOC:	132818558(uox)

LERI:

129700699(uox)

HAKA:

140736700(uox)

PMRN:

116951161

LRJ:

133356464

BFO:

118421545

BBEL:

109484575

SPU:

588974

LPIC:

129277985

APLC:

110981412 110981429

ARUN:

117303010 117303012

AAMU:

139948308 139948427

AFIL:

140166561 140166567 140167612

SKO:

100368654

PFLL:

139152563

DME:	Dmel_CG7171(Uro)

DER:

6541683

DSE:

6611569

DSI:	Dsimw501_GD23486(Dsim_GD23486)

DYA:	Dyak_GE14614

DAN:

6498135

DSR:

110177005

DPO:

4817128

DPE:	113565904 6589893

DMN:

108162944

DWI:	6644051 6644053

DGR:	6563033 6563721

DMO:	Dmoj_GI24222

DNV:

108651295

DHE:

111594568

DVI:	116650345 6632471

CCAT:

101459269 101459637

BOD:	106615260 106615274

BDR:	105231184 105231185

RZE:	108375841 108375849 108381710

AOQ:	129247802 129247902

ALUD:

128863003 128864378

TDA:	119662450 119689551

MDE:

101898809

SCAC:

106083689

LCQ:

111689741

LSQ:

119610979

CVJ:	135952241(Uro)

ECOE:

129951154 129952112 129952546

CLON:

129608349

HIS:

119646430

AGA:

1277530

ACOZ:

120958706

AARA:

120902654

AMER:

121596415

ASTE:

118513006

AMAP:

126565032

AFUN:

125775151

AMOU:

128304219

AMRS:

128710853

AALI:

118458177

ACOS:

131263981

AAG:

5573896

AALB:

109421342 109432570

ASUA:

134204171 134217788

CQU:	CpipJ_CPIJ003456

CPII:

120419666

CBRI:

134829555

CNS:

116346306

BCOO:

119077146

LLL:

129791405

PPAP:

129807138

SOC:

105195412

MPHA:

105838404

AEC:

105151023

ACEP:

105619788

ACOC:

108689533

MZT:

108720882

CCOA:

108778150

PBAR:

105424989

VEM:

105566523

COBS:

139110198

TLN:

139810314

CFO:

105250801

FEX:

115237203

PMEC:

138933713

NVI:

100123613

CSOL:

105362970

TPRE:

106660479

LHT:

122512438

LBD:

127289727

MDL:

103575239

CGLO:

123264328

CTYP:

141529636

FAS:

105267657

DAM:

107040184

AGIF:

122851816

CINS:

118073878

VCAN:

122408307

CCIN:

107266172

DSM:

124405575

NPT:

124211437

NFB:

124175071

NLO:

107225606

NVG:

124297391

AROA:

105689784

NVL:

108565014

APLN:

108738723

PPYR:

116171766

OTU:	111422709 111422711

BMOR:

692784

BMAN:

114245860

MSEX:

115456267

DPL:	KGM_214269

BANY:

112058287

MJU:

123869693

NIQ:

126781382

VCD:

124531348

MCIX:

123669732

PMAC:

106714268

PPOT:

106099909

PXU:

106127743

BPHI:

137922084(Uro)

PRAP:

110994260

PBX:

123708860

PNAP:

125050850

ZCE:

119829197

CCRC:

123706419

LSIN:

126972724

AAGE:

121727552

HAW:

126056768

HZE:

124646187

TNL:

113501006

SLIU:

111352624

OFU:

114355854

ONU:

135087981

ATRA:

106143030

GMW:

113516904

PGW:

126366337

LGLY:

125226917

CSTB:

134741145

CFUM:

141426463(Uro)

CFEL:

113372146 113373825

CCRN:

123305016

BTAB:

109043127

HHAL:

106687253(Uro)

NLU:

111055219

FOC:	113214317 113216932

TPAL:

117639546

CSEC:

111861757

PAME:

138703502(Uro)

SGRE:

126272511

BROR:

134546357

FCD:

110846031

DPX:	DAPPUDRAFT_233847

DMK:

116916130

DPZ:

124328924

PVM:	113823704(Uro)

PJA:	122244711 122244712 122260867

PCHN:

125046135 125046249

PMOO:

119590595 119590596

HAME:

121861661

PCLA:

123762554(Uro)

CQD:	128693828(Uro)

PTRU:

123507136

ESN:

126983077

MNZ:	135196658 135197225

MRJ:	136841622(Uro)

PORN:

139765023(Uro)

EAF:

111718131

LSM:	121119799(Uro)

TCF:

131885325

PPOI:

119107387 119108531

CRG:

105344267

CVN:

111123729

OED:

125678258

MYI:

110442106

PMAX:

117321933

AIRR:

138320356

MCAF:

127729973

MMER:

123550385

RPHI:

132730075 132734451

DPOL:

127837492

MAEA:

128224547

LAK:	106154707 106179546

NVE:

5502102

EPA:

110235296

ATEN:

116298613

ADF:

107344624

AMIL:

114976626

MCAZ:

138029769

MFOO:

137985370

PDAM:

113668211

SPIS:

111329290

ATH:

AT2G26230

ALY:

9330632

CRB:

17894740

CSAT:

104700982 104750279

EUS:	EUTSA_v10021194mg

BRP:

103828734

BNA:	106357878 106452898

BOE:

106301645

RSZ:

108861971

THJ:	104801755 104804947 104823771

CPAP:

110814496

CIT:

102631080

CIC:	CICLE_v10016037mg

PVY:	116105727 116111772

MINC:

123192500 123227169

TCC:

18586835

GRA:

105779785

GHI:	107927605 107943104

GAB:

108460823

HSYR:

120204471

DZI:

111296600

EGR:

104421156

RARG:

115755704

GMX:	100037445(UR2) 547453(UR9)

GSJ:	114369476 114403422

PVU:

137830401

VRA:

106770791

VAR:

108326630

VUN:

114189624

VUM:

124825250

CCAJ:

109815339

APRC:

113871129

MTR:

25483173

TPRA:

123909903

CAM:

101500535

PSAT:

127091038

VVO:

131595876

LJA:

130723567

ADU:	107474240 107474983 107479189 107488723

AIP:	107625265 107625653

AHF:	112727467 112727863 112744064 112749077 112783692 112786132 112790539

LANG:

109336232 109359424

PCIN:

129293432

QSA:	O6P43_008805

FVE:

101304417

AANS:

126801481

RCN:	112189051 112189060

PPER:

18778286

PMUM:

103330981

PAVI:

110758511

PDUL:

117618742

MDM:	103418481 103438828

MSYL:

126610121 126629916

PXB:

103933611

PCOX:

137733842

ZJU:

107413131

MNT:

21395798

CSAV:

115705397

CSV:

101206975

CMO:

103489372

BHJ:

120081363

MCHA:

111018658

CMAX:

111467578 111482298

CMOS:

111449433 111458738

CPEP:

111792556 111801822

RCU:

8272393

MEAN:

126664236 126665112

JCU:

105649139

HBR:	110664227 110667476

MESC:

110625006

POP:

7491607

PEU:

105125425

PALZ:

118060109

PNZ:

133696089

JRE:

109002171

CILL:

122291413

CAVE:

132168045

AGLU:

133880381

QLO:

115984267

TWL:

119989287

VVI:

100232988

VRI:	117927573 117929383

SLY:

100037732

SPEN:

107002894

SOT:

102581180

SSTN:

125851616

SDUL:

129900312

CANN:

107851994

LBB:

132612606

NTA:	107791874 107813779

NSY:

104211356

NTO:

104091371

NAU:

109212210

INI:

109147930

ITR:

116000078

SIND:

105161011

OEU:

111375160

EGT:

105977732

SSPL:

121749463 121792365

SMIL:

130997402

SHIS:

125223424

APAN:

127259913

PEBU:

140816643

HAN:

110925667

ECAD:

122603156

LSV:

111916296

CCAV:

112524727

DCR:

108205953

CSIN:

114302288

RVL:

131301237

AEW:

130753430

DLT:

127797085

BVG:

104907803

SOE:

110804304

CQI:	110723244 110737418

ATRI:

130828809

SLAF:

141638912

MOF:

131165276

NNU:	104590108 104601391

MING:

122058293

TSS:

122642274

PSOM:

113313717 113323856

OSA:

4324793

DOSA:

Os01g0865100

OBR:

102704100

OGL:

127763296

BDI:

100845980

ATS:

109743862

TDC:	119269687 119277699

TAES:

100037659 123062701 123079860

LPER:

127344314

LRD:	124661048 124661191

SBI:

110433901

ZMA:

100274529

MFLO:

136453590 136453666 136459511

SITA:

101785812

SVS:

117858963

PVIR:

120673542 120708771

PHAI:

112895402

PAUA:

133909234

TANG:

140772527

PDA:

103721005

EGU:	105032853 105034366

MUS:

135608071

ZOF:	122041864 122046387

DCT:	110092579 110114143

PEQ:

110022445

AOF:

109836810

MSIN:

131252441

ACAK:

137951574

NCOL:

116252767

ATR:

18444423

CJF:

131041187

SMO:	SELMODRAFT_156451 SELMODRAFT_172716

PPP:

112291670

CRE:	CHLRE_12g504950v5

VCN:	VOLCADRAFT_73602

CSL:	COCSUDRAFT_52384

CVR:	CHLNCDRAFT_20118

BPG:	Bathy08g04420

MIS:	MICPUN_64532

GSL:	Gasu_65630

CCP:	CHC_T00000418001

KLA:	KLLA0_E10935g

KMX:	KLMA_20057

LTH:	KLTH0H09262g

ZRO:	ZYRO0G09482g

TGB:	HG536_0D04740

TDL:	TDEL_0F02670(TDEL0F02670)

ZMK:	HG535_0B05580

SLUD:

SCDLUD_001535

DHA:	DEHA2A07194g

PIC:	PICST_40781(URO1)

PGU:	PGUG_02092

SPAA:

SPAPADRAFT_136352

LEL:	PVL30_001151

LBG:	92209704(LODBEIA_P45080)

CAL:	CAALFM_C200180CA(CaO19.2114)

CTP:	CTRG_01093

COT:	CORT_0A12930

CDU:	CD36_15160

CLU:	CLUG_05509

CLUS:

A9F13_16g00825

CAUR:

CJI96_0004710

ASAU:

88173163(PUMCH_002098)

PPA:	PAS_chr2-2_0279

PKZ:	C5L36_0B08050

BNN:	FOA43_000942

BBRX:

BRETT_003773

OPA:	HPODL_00339

YLI:	2908329(YALI2_F00181g)

SLB:	AWJ20_2522

NCR:

NCU07853

NTE:	NEUTE1DRAFT62263(NEUTE1DRAFT_62263)

SMP:	10807967(SMAC4_02127)

PAN:	PODANSg5539

PBEL:

QC761_711330

PPSD:

QC762_711330

PPSP:

QC763_711330

PPSA:

QC764_711330

TTT:	THITE_2171067

MTM:	MYCTH_2315024

CTHR:

CTHT_0071370

RTHE:

98122089(VTJ83DRAFT_1300)

MGR:

MGG_05283

PPEI:

PpBr36_03665

PGRI:

PgNI_09434

TMN:	UCRPA7_3858

SSCK:

SPSK_07787

FGR:	FGSG_04126

FPU:	FPSE_00146

FPOA:

FPOAC1_006573

FVN:	FVRRES_07182

FVR:	FVEG_10312

FOX:	FOXG_11511

NHE:	NECHADRAFT_81764

FFC:	NCS54_00832800

FKR:	NCS57_00876000

FMU:	J7337_011585

TRE:	TRIREDRAFT_76381

TRR:	M419DRAFT_24207

TATV:

25775799(TrAtP1_009464)

TASP:

36612578(TrAFT101_011650)

MAW:	19245969(J3458_001022)

MAJ:

MAA_02492

MBRN:

26240096(uaz)

PCHM:

VFPPC_14369

CMT:

CCM_09432

AMUS:

LMH87_010805

PLJ:	28884496(PLICBS_005750)

PTKZ:

JDV02_003613

VAL:	VDBG_06639

VDA:	VDAG_05692

CFJ:	CFIO01_08679

CLUP:

CLUP02_02622

CHIG:

CH63R_01989

CDET:

87936714(CDEST_00211)

SAPO:

SAPIO_CDS2119

ELA:	UCREL1_184

PFY:	PFICI_05327

SSL:	SS1G_00106

BFU:	BCIN_03g06830

MBE:

MBM_07067

PSCO:

LY89DRAFT_688903

GLZ:	GLAREA_06901

ANI:	ANIA_09470

AFM:	AFUA_2G10520

ACT:	ACLA_069530

NFI:	NFIA_085890

AOR:	AO090011000588

ANG:	An02g06030 An03g02330

AFV:	AFLA_007981

ALUC:

AKAW2_21127A AKAW2_40206S

ACHE:

ACHE_40565A

APUU:

APUU_11005A

PCS:	N7525_004273

PDP:	PDIP_63940

POU:	POX_f07967

TMF:	EYB26_003493

TRG:	TRUGW13939_07826

CIM:	CIMG_04344

CPW:	9697343(D8B26_003718)

URE:	UREG_01592

ABE:

ARB_05777

TVE:

TRV_04465

PBL:	PAAG_01437

PBN:	PADG_00331

AJE:	HCAG_08071

BGH:	BDBG_07100

PNO:	SNOG_08332

PTE:

PTT_12595

PTRR:

6346461(PtrM4_150890)

BZE:	COCCADRAFT_86661

BSC:	COCSADRAFT_124032

BOR:	COCMIDRAFT_82479

AALT:

CC77DRAFT_1017270

ADAC:

96081129(ACET3X_000807)

ARAB:

EKO05_0004831

ZTR:	MYCGRDRAFT_70045

PFJ:	MYCFIDRAFT_184206

FFU:	CLAFUR5_09863

CBET:

CB0940_06429

BCOM:

BAUCODRAFT_114390

NPA:	UCRNP2_5250

TML:	GSTUM_00004503001

SPO:	2538957(uro1)

SOM:	SOMG_02998(uro1)

CNE:

CNI02420

CNB:

CNBH2300

CNG:	CNAG_04307

CGI:	CGB_H3440W

CDEU:

CNBG_2745

CDEC:

89989316(IAS62_002543)

CTEG:

91991636(I308_104780)

CBAS:

91983314(I312_103269)

CDEP:

91090280(L203_106072)

KMG:	30165911(I203_103391)

KNE:	92181212(IAR55_003954)

KBI:	30211781(I302_108252)

KSH:	87959314(IL334_007184)

KER:	91100546(V865_001742)

TMS:	TREMEDRAFT_70604

TASA:

A1Q1_03024

CCAC:

CcaHIS019_0305880(CcaverHIS019_0305880)

TVS:	TRAVEDRAFT_156281

DSQ:	DICSQDRAFT_145006 DICSQDRAFT_70560

PCO:	PHACADRAFT_251616

SHS:	STEHIDRAFT_117903

HIR:	HETIRDRAFT_439423

PSQ:	PUNSTDRAFT_91772

ADL:	AURDEDRAFT_59877

FME:	FOMMEDRAFT_102646

GTR:	GLOTRDRAFT_62332

LBC:	LACBIDRAFT_190858

CCI:	CC1G_04058

ABP:	AGABI1DRAFT42333(AGABI1DRAFT_42333)

ABV:	AGABI2DRAFT65743(AGABI2DRAFT_65743)

PCUB:

JR316_0006458

MPR:	MPER_10554

MRR:	Moror_16610

E1B28_005762

CPUT:

CONPUDRAFT_118951

SLA:	SERLADRAFT_356374

WSE:	WALSEDRAFT_59270

WIC:	J056_002062

UMA:	UMAG_00672

PFP:	PFL1_00057

SGRA:

EX895_000902

PGR:	PGTG_04959

PTRC:

PtA15_11A497

PSTR:

Pst134EA_017388

MLR:	MELLADRAFT_39009

RIE:	OCT59_027787

DDI:	DDB_G0286427(uox)

DPP:	DICPUDRAFT_49836

DFA:	DFA_04065(uox)

ACAN:

ACA1_220120

PTI:	PHATRDRAFT_29736

PIF:	PITG_18435 PITG_18437

PSOJ:

PHYSODRAFT_469313 PHYSODRAFT_477479

SPAR:

SPRG_09685

NGR:	NAEGRDRAFT_80401

GTT:	GUITHDRAFT_161824

CARU:

P0E69_15805(pucL)

NIG:	C1N62_13265(pucL)

NEN:	NCHU2750_43570(uaZ)

BQB:	J4P68_0017380(pucL)

BROS:

QUH67_27135(pucL)

BRAA:

NL528_14580(pucL)

RBK:	E0H22_18805(pucL)

VGO:	GJW-30_1_02473(uox)

TRB:	HB776_14910(pucL)

TALZ:

RPMA_21015(pucL)

TARD:

RSO67_08635(pucL)

TARV:

FIU28_18610(pucL)

STAR:

G3545_19125(pucL)

SNO:

Snov_3388

ANC:	GBB76_11060(pucL)

APRA:

G3A50_10785(pucL)

APOL:

K9D25_07670(pucL)

MRD:	Mrad2831_0199

MET:

M446_5249

MNO:

Mnod_5813

MOR:	MOC_0208(pucL)

MAQU:

Maq22A_1p31805

MPHY:

MCBMB27_05183

MEE:	DA075_04800(pucL)

METX:

A3862_01265

METS:

DK389_23800(pucL)

METI:

DK427_21980(pucL)

MMES:

MMSR116_07040(pucL)

MTEA:

DK419_18885(pucL)

MIND:

mvi_57850

MOG:	MMB17_23025(pucL)

MTAD:

M6G65_01020(pucL)

MFUJ:

ABC766_09690(pucL)

MENS:

LOK46_01005(pucL)

BBAR:

RHAL1_01325

PSIN:

CAK95_13210

LIZ:	LGH83_16080(pucL)

SCL:

sce4023

SCU:	SCE1572_24240

LUO:	HHL09_09775(pucL)

LUP:	ABWK72_18385(pucL)

MFF:	MFFC18_06180(uox)

AAGG:

ETAA8_33800(uox)

LPAV:

PLANPX_2074

LLH:	I41_18920(uox)

PND:	Pla175_41560(uox)

AMOB:

HG15A2_03670(uox)

BMEI:

Spa11_23740(uox)

SACI:

Sinac_4646

PHM:	PSMK_30590

ACM:	AciX9_2872

GMA:	AciX8_0720

GRW:	FTO74_13545(pucL)

GRB:	GOB94_05375(pucL)

TSA:	AciPR4_3479

TRS:	Terro_0864

TALB:

FTW19_00715(pucL)

ABAS:

ACPOL_2451

ADIN:

H7849_02395(pucL)

TGI:	RBB81_20565(pucL)

TEMP:

RBB75_13730(pucL)

TPSC:

RBB77_19385(pucL)

SUS:

Acid_0359

ABAC:

LuPra_02263(pucL_1)

CPI:

Cpin_6768

CHIH:

GWR21_13205(pucL)

CFIL:

MYF79_29545(pucL)

CSAC:

SIO70_29990(pucL)

NKO:	Niako_0442

SPIK:

EXU85_15930(pucL)

SPIB:

G8759_09020(pucL)

SFOL:

H3H32_12465(pucL)

SENF:

GJR95_03755(pucL)

HYP:	A0257_17680

HYZ:	AXW84_04225

HYJ:	FHG12_10350(pucL)

HQI:	H9L05_03275(pucL)

HTS:	HMJ29_15970(pucL)

BSU:	BSU32450(pucL)

BSR:	I33_3345(pucL)

BSL:

A7A1_2459

BSH:	BSU6051_32450(pucL)

BSY:	I653_15640

BSUT:

BSUB_03463(pucL)

BSUL:

BSUA_03463(pucL)

BSUS:

Q433_17750

BSO:	BSNT_09727(pucL)

BSN:	BSn5_07115

BSQ:	B657_32450(pucL)

BSX:	C663_3103(pucL)

BSP:	U712_16180

BSS:	BSUW23_15825(pucL)

BST:	GYO_3538(pucL)

BIT:	BIS30_05785

BSIA:

CWD84_04465

BHT:	DIC78_14975

BMOJ:

HC660_31270(pucL)

BTEQ:

G4P54_16535(pucL)

BIQ:	AN935_16280

BSTR:

QI003_19590(pucL)

BSM:	BSM4216_2147

BCAB:

EFK13_16635(pucL)

BRY:	M0696_16330(pucL)

BJS:

MY9_3258

BACI:

B1NLA3E_12615

BACY:

QF06_14540

BACL:

BS34A_35410(pucL)

BALM:

BsLM_3241

BACS:

AUL54_14940

BEO:

BEH_09915

BFX:	BC359_11590

BHA:

BH0759

BCL:

ABC3735

BGI:	BGM20_10325

HSAN:

MUN89_17670(pucL)

BMUR:

ABE28_003430

PFRI:

L8956_22270(pucL)

PERJ:

JNUCC41_04735(pucL)

SCIA:

HUG15_17705(pucL)

NCM:	QNK12_07465(pucL) QNK12_14035(pucL)

MEKU:

HUW50_12970(pucL)

MLIT:

KDJ21_024500(pucL)

MENL:

MVE64_20450(pucL)

MEBZ:

LPC09_06435(pucL)

MRL:	WCV66_26460(pucL)

BBEV:

BBEV_2689(uao)

BSE:

Bsel_0582

AHAL:

FTX54_001780(pucL)

ACHP:

QR721_01200(pucL) QR721_01780(pucL) QR721_01785(pucL) QR721_01790(pucL) QR721_01795(pucL) QR721_01800(pucL)

GGH:	GHH_c21820(pucL)

GEA:	GARCT_02054(uao)

PCAL:

BV455_03585(uao)

PJD:	Pjdr2_3315

PMS:	KNP414_03236(uao)

PMQ:	PM3016_3460

PMW:

B2K_17880

POD:	PODO_06605

PAEF:

R50345_07070

PAEJ:

H70737_06880

PNP:	IJ22_16630

PXL:	BS614_20795

PYG:	AWM70_00910

PSWU:

SY83_16740

PCX:	LPB68_13750

PPSC:

EHS13_20750(pucL)

PALB:

EJC50_19205(pucL)

PRZ:	GZH47_00525(pucL)

PLYC:

GXP70_15750(pucL)

PUI:	PUW25_15715(pucL)

PMAH:

PTQ21_21060(pucL)

PAMY:

P9222_19655(pucL)

PPOG:

QPK24_15065(pucL)

PEZZ:

HW560_22780(pucL)

PROO:

MJB10_02600(pucL)

CHEB:

HH215_09665(pucL)

BTS:

Btus_2019

KPUL:

GXN76_09800(pucL)

KEB:	GXN75_10260(pucL)

ERZ:	ER308_09430(pucL)

EUZ:	DVS28_a3619

MDX:	BTO20_17345

MSPG:

F6B93_21710(pucL)

MSM:	MSMEG_1296

MSG:	MSMEI_1258

MSB:	LJ00_06455

MSN:	LI99_06455

MSH:	LI98_06455

MMAG:

MMAD_14320

MARZ:

MARA_24760

MAUB:

MAUB_52830

MMUC:

C1S78_010080(pucL)

MMAT:

MMAGJ_63580

MBOK:

MBOE_38490

MSEI:

MSEDJ_03270

MGO:	AFA91_32355

MGRO:

FZ046_12950(pucL)

MYQ:	TUM20985_44440

MFLU:

HZU40_12570(pucL)

MKR:	MKOR_07400

MPAK:

MIU77_08040(pucL)

MAB:

MAB_2929c

MMV:	MYCMA_1623

MABB:

MASS_2864

MABL:

MMASJCM_2938

MCHE:

BB28_14755

MIZ:	BAB75_15845

MSTE:

MSTE_02898

MSAO:

MYCSP_13255

MSAL:

DSM43276_02713(uox)

ASD:

AS9A_4198

NFA:

NFA_52420

NFR:	ERS450000_04639(uox)

NBR:	O3I_016180 O3I_039235

NSL:	BOX37_30035

NSR:	NS506_06726

NTP:	CRH09_09400(pucL) CRH09_28995(pucL)

NOZ:	DMB37_18055(pucL) DMB37_37640(pucL)

NOD:	FOH10_19465(pucL) FOH10_19505(pucL) FOH10_22330(pucL)

NAH:	F5544_19135(pucL) F5544_19190(pucL) F5544_41710(pucL)

NAD:	NCTC11293_00174(uox)

NWL:	NWFMUON74_18950 NWFMUON74_55710

NIE:	KV110_18175(pucL) KV110_38435(pucL)

NTC:	KHQ06_14250(pucL) KHQ06_34870(pucL)

NHU:	H0264_26720(pucL) H0264_26810(pucL) H0264_33950(pucL)

NYA:	LTV02_07860(pucL) LTV02_39005(pucL)

NGP:	LTT66_09200(pucL)

NSPU:

IFM12276_58320

NYU:	D7D52_09265(pucL) D7D52_32570(pucL)

NVU:	V7968_04390(pucL) V7968_24035(pucL)

RHA:	RHA1_ro01568 RHA1_ro04509

RER:

RER_21140

REY:

O5Y_10090

REB:	XU06_10315

RQI:	C1M55_10755(pucL)

ROP:	ROP_12690 ROP_44290

ROA:	Pd630_LPD00958 Pd630_LPD05707

RPY:	Y013_22670

RBY:	CEJ39_08885(pucL)

RHB:	NY08_1727 NY08_3502

RAV:	AAT18_25545

RHQ:	IM25_12100

RHOD:

AOT96_20935

RRT:	4535765_01297(uox)

RCR:	NCTC10994_02749(uox)

RTM:	G4H71_07535(pucL)

RKO:	JWS14_08055(pucL) JWS14_24360(pucL)

RGO:	KYT97_07985(pucL)

ROZ:	CBI38_03995

RPSK:

JWS13_20565(pucL) JWS13_38140(pucL)

RANT:

RHODO2019_13760(pucL)

RHOP:

D8W71_13705(pucL) D8W71_20290(pucL)

RHOO:

RA302_10465(pucL)

RHOU:

KZJ41_26995(pucL)

RHOW:

A4U64_25665

RHOJ:

JVH1_13790(pucL)

RHOS:

QWW67_16000(pucL)

RHOQ:

QWW98_16000(pucL)

RHOH:

CPI83_18735(pucL)

RHOX:

RBB84_02430(pucL)

RHJS:

OYT95_14385(pucL) OYT95_30800(pucL)

RSF:	OED52_05570(pucL)

RHZQ:

GO592_27130(pucL)

RHZG:

BO226_02595

RHBH:

A0W34_10425

RHPD:

U9J23_06400(pucL)

RFA:	A3L23_00088(uox)

RHS:	A3Q41_03326(uox)

WHR:	OG579_10405(pucL)

GAM:	GII34_19405(pucL)

TSM:	ASU32_07280

TPUL:

TPB0596_33050

TSD:	MTP03_13620

SCO:	SCO6211(SC9G1.01)

SALB:

XNR_0633

SMA:	SAVERM_2018(pucL)

SGR:

SGR_1309

SGB:

WQO_28725

SFI:

SFUL_6171

SANL:

KZO11_30820(pucL)

SGRF:

SGFS_031640

SCYE:

R2B67_05120(pucL)

SCB:	SCAB_18521

SSX:	SACTE_5453

SVL:	Strvi_2410

SHY:

SHJG_7271

SHO:	SHJGH_7031

SRC:	M271_13630

SMAL:

SMALA_6025

SSOI:

I1A49_33990(pucL)

SFA:

Sfla_1052

SBH:

SBI_02950

SVE:	SVEN_2512 SVEN_6093

SDV:	BN159_2098(uox)

SALS:

SLNWT_0615

STRP:

F750_5793

SCI:	B446_29175

SLV:	SLIV_07080

SGU:	SGLAU_26725

SVT:	SVTN_13450 SVTN_30295

STRE:

GZL_02614

SCW:	TU94_26730

SLD:

T261_1848

SLC:	SL103_25185

SXI:	SXIM_47140

STRM:

M444_18340 M444_27195

STRC:

AA958_28425

SAMB:

SAM23877_5951(uox)

SPRI:

SPRI_1552

SCZ:	ABE83_05550

SCX:	AS200_11350

SRW:	TUE45_06834(uox)

STRF:

ASR50_28400

SLE:	sle_14680(sle_14680)

SPAV:

Spa2297_26325

STRT:

A8713_25925

SCLF:

BB341_03990

SGS:	AVL59_12990

STSI:

A4E84_32100

SKY:	D0C37_04465(pucL)

SALW:

CP975_29065(pucL)

SGM:	GCM10017557_15640

SCAD:

DN051_10065(pucL)

SPHW:

NFX46_10560(pucL)

SLS:	SLINC_6745

SNR:	SNOUR_11160

SALU:

DC74_6400

SALL:

SAZ_32150

SPLU:

LK06_027275

STRD:

NI25_08290

SNW:	BBN63_05825

SAUO:

BV401_33935

SSIA:

A7J05_07840

SVU:	B1H20_29460

SPUN:

BFF78_10110

SGV:	B1H19_31945

SLAU:

SLA_6161

SALF:

SMD44_06844

SALJ:

SMD11_1431

SLX:	SLAV_08750(uox1) SLAV_19850(uox2)

STRO:

STRMOE7_30430

SFK:

KY5_6544

SNZ:	DC008_27920(pucL)

SGE:	DWG14_01832(uox)

SRJ:

SRO_1626

SLK:	SLUN_31845(pucL)

SDX:	C4B68_08275(pucL)

SGD:	ELQ87_07305(pucL)

SQZ:	FQU76_27825(pucL)

SCYA:

EJ357_37535(pucL)

SAST:

CD934_05370(pucL)

STIR:

DDW44_25770(pucL)

SKA:	CP970_08370(pucL)

SGZ:	C0216_00835(pucL) C0216_09630(pucL)

SVN:	CP980_06850(pucL) CP980_16355(pucL)

SNK:	CP967_04940(pucL)

SHAW:

CEB94_32780(pucL)

SRK:	FGW37_25900(pucL)

SFIC:

EIZ62_05855(pucL)

SGAL:

CP966_29230(pucL)

SSPO:

DDQ41_27250(pucL)

SVR:	CP971_05920(pucL)

SPAD:

DVK44_29130(pucL)

SFY:	GFH48_10320(pucL)

SAQU:

EJC51_37370(pucL)

SGF:	HEP81_01812(pucL)

SCAV:

CVT27_28220(pucL)

SSEO:

D0Z67_23530(pucL)

SBY:	H7H31_05850(pucL)

SRIM:

CP984_07770(pucL)

SSUB:

CP968_07340(pucL) CP968_16230(pucL)

SPHV:

F9278_39005(pucL)

SCIN:

CP977_12085(pucL) CP977_27595(pucL)

SFUG:

CNQ36_26555(pucL)

SPAC:

B1H29_07330

STSU:

B7R87_28210

SCHA:

CP983_08880(pucL)

SGX:	H4W23_14535(pucL) H4W23_31460(pucL)

SCOE:

CP976_34700(pucL)

SBAT:

G4Z16_05235(pucL)

SSPB:

CP982_32520(pucL)

SNF:	JYK04_04550(uox_1) JYK04_06648(uox_2)

SPLA:

CP981_30710(pucL)

SBRO:

GQF42_33475(pucL)

STUI:

GCM10017668_57370

SATA:

C5746_33465(pucL)

SCHF:

IPT68_29600(pucL)

SHUN:

DWB77_01706(uox)

SHAR:

HUT13_23620(pucL)

SCYG:

S1361_31105(uox)

SFEU:

IM697_31620(pucL)

SLIA:

HA039_06290(pucL)

SDW:	K7C20_29340(pucL)

SVD:	CP969_30170(pucL)

SCAL:

I6J39_29300(pucL)

SAUH:

SU9_028245(pucL)

SMOB:

J7W19_25710(pucL)

SPRA:

CP972_28745(pucL)

SPEU:

CGZ69_29805(pucL)

SROI:

IAG44_08030(pucL)

SXN:	IAG42_07000(pucL) IAG42_33225(pucL)

SGJ:	IAG43_26550(pucL)

SHK:	J2N69_30500(pucL)

SANU:

K7396_07820(pucL)

STRY:

EQG64_29500(pucL)

SDD:	D9753_06965(pucL)

SACT:

DMT42_30625(pucL)

SMAO:

CAG99_03235

SGOB:

test1122_22950(pucL)

SINE:

KI385_35295(pucL)

SLF:	JEQ17_11085(pucL)

SDEC:

L3078_37050(pucL)

SAOV:

G3H79_06600(pucL)

SDUR:

M4V62_10215(pucL)

SYAN:

NRK68_17710(pucL) NRK68_27690(pucL)

SRUG:

F0345_24495(pucL)

SAKB:

K1J60_09385(pucL)

STAA:

LDH80_08970(pucL)

SNIG:

HEK616_48850

SVIO:

HWN34_03870(pucL)

SCAE:

IHE65_08495(pucL)

STUB:

MMF93_26675(pucL)

SSPN:

LXH13_31240(pucL)

SCIR:

STRCI_006464(pucL)

SXT:	KPP03845_103753(uox_1) KPP03845_105894(uox_2)

SLON:

LGI35_33860(pucL)

SDRZ:

NEH16_04945(pucL)

STUD:

STRTU_001364(pucL)

STEE:

F3L20_13210(pucL)

SENG:

OJ254_29170(pucL)

SGK:	PET44_17090(pucL) PET44_25720(pucL)

SANT:

QR300_11575(pucL)

SYUN:

MOV08_10960(pucL)

SARG:

HKX69_06795(pucL)

SJN:	RI060_08015(pucL)

SCYN:

N8I84_31505(pucL)

SOV:	QZH56_06110(pucL)

SFIY:

F0344_04425(pucL)

SHAU:

K9S39_11555(pucL)

SKG:	KJK29_06160(pucL)

SCOA:

QU709_07655(pucL)

SLAI:

P8A22_06625(pucL)

SROC:

RGF97_04805(pucL) RGF97_30875(pucL)

SFP:	QUY26_07625(pucL)

SCHG:

NRO40_24405(pucL)

STTN:

BSL84_17255 BSL84_27035

SINN:

ABB07_07390

STRZ:

OYE22_05665(pucL)

SCAY:

PYS65_06980(pucL)

KBU:	Q4V64_41795(pucL)

SARM:

DVA86_00150(pucL)

SPRF:

K4G22_25385(pucL)

SLUO:

PS467_31300(pucL)

STPB:

QR97_32105

SRPA:

HEP86_31935(pucL)

SMIB:

SMIR_05830(pucL)

SCAJ:

O1G22_09160(pucL)

STRW:

QHG49_07605(pucL)

STRL:

HEP84_39725(pucL)

STSD:

HEP87_40590(pucL)

SRPZ:

HEP85_31095(pucL)

SCHE:

QRN89_28120(pucL)

SGLY:

P8A20_05900(pucL)

SCAT:

P8A18_28550(pucL)

STII:

DRB96_08610(pucL) DRB96_22755(pucL)

STIC:

DRB89_12155(pucL) DRB89_18880(pucL)

SABD:

N8I86_29585(pucL)

STRV:

EZV63_29425(pucL)

SPAZ:

ABXI76_05860(pucL)

SPIH:

ABXR15_03640(pucL)

SMOD:

POD33_24980(pucL)

SPOF:

P8A21_32440(pucL)

STBR:

ABDE16_20860(pucL)

SGRO:

UBV09_27470(pucL)

STAC:

ABII15_30910(pucL)

STVB:

OH133_05675(pucL)

SSOC:

ABZO31_11180(pucL) ABZO31_26825(pucL)

SSLI:

R2D22_07520(pucL) R2D22_24110(pucL)

STYI:

C9F11_31655(uox)

SCIT:

V2W30_31800(pucL)

SSIR:

WAB15_32290(pucL)

STRJ:

H7827_04350(pucL)

SEXP:

SLV14_001643(pucL)

SCT:

SCAT_4779

SCY:	SCATT_47730

KSK:

KSE_63370

KAB:	B7C62_30590

KAU:	B6264_01120

KIT:	CFP65_6316

KIS:	HUT16_29980(pucL)

KCH:	O1G21_08545(pucL)

KCM:	ABWK59_27145(pucL)

KNB:	ACF9IK_07545(pucL)

STRI:

C7M71_005125(pucL)

PPOD:

AB0761_29875(pucL)

STRH:

GXP74_11090(pucL)

ABRY:

NYE86_24550(pucL)

AGLA:

OIE69_11255(pucL)

AREV:

RVR_8117

LXL:	KDY119_03106

PSIC:

J4E96_12620(pucL)

CMC:

CMN_00267

CCAF:

FGD68_03405(pucL)

MIO:	AOA12_01320

MCW:	A8L33_04275

MLV:	CVS47_02416(uox)

MRN:	K8F61_18255(pucL)

MAZA:

NFX31_15890(pucL)

MRG:	SM116_02775(pucL)

MCHN:

HCR76_11440(pucL)

RTN:	A6122_1518

RRY:	C1O28_06925(pucL)

RIA:	C7V51_05370(pucL)

RFS:	C1I64_04450(pucL)

RTE:	GSU10_08445(pucL)

RATH:

GSU68_10170(pucL)

CUM:	NI26_12225

CUB:	BJK06_04275

CUG:	C1N91_12385(pucL)

CCIT:

QPK07_12580(pucL)

CURT:

LCG91_12180(pucL)

CURZ:

LQK89_12565(pucL)

FRP:	AX769_03080

FSB:	GCM10025867_06460

AGY:	ATC03_05300

AGM:	DCE93_10615(pucL)

AMAU:

DSM26151_07360(uox)

ASOI:

MTP13_00050(pucL)

AMAV:

GCM10025877_06150

CART:

PA27867_1468

CRY:	B7495_07110(pucL)

CPHY:

B5808_11810

HUM:	DVJ78_09150(pucL)

GRY:	D7I44_02135(pucL) D7I44_04275(pucL)

MANT:

BHD05_06545

HEA:	HL652_10655(pucL)

HEH:	L3i23_01990

FRN:	F1C15_05910(pucL)

GLN:	F1C58_03565(pucL)

AGX:	AGREI_1041(uox)

SUBT:

KPL76_08265(pucL)

SUBA:

LQ955_09995(pucL)

NAEI:

GCM126_15740

AOG:	LH407_11320(pucL)

ART:

Arth_3427

ARR:	ARUE_c35390(uox)

ARL:	AFL94_16680

ARE:	AL755_03375

ARW:	MB46_14750

ARY:	ATC04_01015

ARU:	ASPU41_03895

ARQ:	BWQ92_13885

ARN:	CGK93_19080(pucL)

ARX:	ARZXY2_326

ACRY:

AC20117_05940

ARTH:

C3B78_16720(pucL)

AJG:	KKR91_16125(pucL)

ASUN:

KG104_17015(pucL)

ASUF:

MNQ99_01645(pucL)

APOA:

J0916_01035(pucL)

AWW:	G8758_11630(pucL)

ACAO:

NF551_15690(pucL)

AZH:	MUK71_14905(pucL)

AGEG:

MUG94_16285(pucL)

AOD:	Q8Z05_04105(pucL)

AZX:	N2K95_14695(pucL)

AJR:	N2K98_15695(pucL)

ARTZ:

FCN77_21600(pucL)

ARTQ:

CGQ24_00975(pucL)

ARTO:

PJ267_16605(pucL)

ARTT:

IG195_11535(pucL)

ARTC:

KY499_11520(pucL)

ARTL:

ArtHe_10940(pucL) ArtHe_13935(pucL)

AAU:

AAur_3402

PUE:	FV140_18025(pucL)

PNV:	JMY29_16285(pucL)

PAYJ:

HMI59_03900(pucL)

PAGO:

IRJ34_16705(pucL)

PAYN:

HMI60_16355(pucL)

PHRZ:

QN084_06890(pucL)

ARZ:	AUT26_16280

ACH:

Achl_3208

APN:	Asphe3_33450

PSUL:

AU252_13710

PSNI:

NIBR502771_08300(pucL)

PSEY:

GU243_13025(pucL)

PDEL:

JCQ34_16230(pucL)

POK:	SMD14_17020(pucL)

PSLS:

KTR40_15685(pucL)

PSFE:

NG819_06455(pucL)

PQA:	WHH00_02435(pucL)

AAI:	AARI_33710

GAR:	AOZ07_17635

GCR:	GcLGCM259_2798

GLU:	F0M17_16430(pucL)

GPR:	JQN66_17120(pucL)

GMI:	NMP99_17010(pucL)

GMY:	XH9_08860(pucL)

GNC:	QQS42_17030(pucL)

GLM:	N6V40_03150(pucL)

GEY:	QMQ05_16560(pucL)

KRH:

KRH_19780

KFV:	AS188_04945

KRS:	EQG70_15655(pucL)

KVR:	CIB50_0001106(uox)

SATK:

SA2016_3345

CCYC:

SCMU_33800

SPUE:

AB5L97_15795(pucL)

PAEY:

KUF55_18075(pucL)

BFA:	Bfae_08250

BRV:	CFK39_12195(pucL)

BRZ:	CFK38_15305(pucL)

BRR:	C1N80_00895(pucL)

BRAC:

RBL05_00175(pucL)

LMOI:

VV02_25695

YIM:	J5M86_13145(pucL)

ALX:	LVQ62_04540(pucL)

BEI:	GCM100_37910

CET:	B8281_09725

CCEU:

CBR64_01400

CPRT:

FIC82_008685(pucL)

PROU:

AB1046_10095(pucL)

CFL:

Cfla_2783

CDON:

KKR89_13785(pucL)

CWAN:

KG103_14115(pucL)

CFEN:

KG102_05300(pucL)

CWN:	NP075_14465(pucL)

CXIE:

NP048_14080(pucL)

PSEI:

GCE65_05025(pucL)

PSEK:

GCM125_27410

KNO:	V6K52_18100(pucL)

SERJ:

SGUI_2186

ORN:	DV701_17990(pucL)

ORZ:	FNH13_01510(pucL)

OCP:	NF557_05505(pucL)

OFA:	NF556_03215(pucL)

BLY:	A2T55_04520

BLIN:

BLSMQ_0835

BLUT:

EW640_09275(pucL)

BCAU:

I6G59_07265(pucL)

BSPO:

L1F31_04560(pucL)

BREB:

PGC08_04565(pucL)

BREJ:

LJ362_03445(pucL)

BKR:	AAFP32_03280(pucL)

SEVR:

LWF01_15100(pucL) LWF01_16870(pucL)

GYU:	FE374_12735(pucL)

GEW:	MF406_00925(pucL)

DSS:	GCM25873_01620

MPH:

MLP_22140

NCA:

Noca_1142

NOY:	EXE57_07460(pucL)

NSN:	EXE58_12285(pucL)

NANO:

G5V58_13160(pucL)

NARO:

CFH99_02280(pucL)

NCQ:	K6T13_03965(pucL)

NMAR:

HPC71_05090(pucL)

NFC:	KG111_13895(pucL)

NBI:	SHK19_04485(pucL)

NOCR:

OSR43_05245(pucL)

NOCL:

KM427_20130(pucL)

AER:	AERYTH_00570

ASEZ:

H9L21_04730(pucL)

ADB:	NP095_04680(pucL)

AWN:	NQV15_03255(pucL)

MUZ:	H4N58_17085(pucL)

MQR:	AB3M34_19100(pucL)

SGRG:

L0C25_00170(pucL)

NBT:	KLP28_12260(pucL)

KQI:	F1D05_01410(pucL)

KSL:	OG809_13265(pucL)

KRI:	OX958_14435(pucL)

NDA:

Ndas_0718

NAL:	B005_3625(pucL)

NGV:	CDO52_20165(pucL)

NEX:	NE857_10685(pucL)

NEC:	KGD82_19385(pucL)

NAKE:

KGD83_22135(pucL)

NCG:	KGD84_23775(pucL)

SNAH:

OUQ99_23580(pucL)

SAIU:

J4H86_24115(pucL)

ACTW:

F7P10_32560(pucL)

AGRA:

AGRA3207_006116(pucL)

AMAZ:

LUW76_38220(pucL)

ACIR:

OG979_07840(pucL)

AWS:	ACN3XK_46560(pucL) ACN3XK_47305(pucL)

SPIQ:

OHA34_32020(pucL)

ACTQ:

OG417_23090(pucL)

SRO:

Sros_2773

NOA:	BKM31_28615

NOW:	GBF35_17930(pucL)

NCX:	Nocox_14920(uox)

NGN:	LCN96_17925(pucL)

NFS:	OIE67_28665(pucL)

TBI:

Tbis_2592

MHAI:

OHB01_23745(pucL)

FRA:	Francci3_1910

FAL:

FRAAL4508

FRE:	Franean1_2243

FSY:	FsymDg_1782

FRI:	FraEuI1c_4801

NML:	Namu_0238 Namu_0250

NAKA:

H7F38_02225(pucL)

GOB:

Gobs_2838

BLAP:

MVA48_15790(pucL)

BBRG:

U6N30_30680(pucL)

MMAR:

MODMU_0113(uox)

MOM:	KUM42_10990(pucL)

KRA:

Krad_2071

SEN:

SACE_6736

SACG:

FDZ84_08590(pucL)

AMD:

AMED_1926

AMN:

RAM_09770

AMM:

AMES_1910

AMZ:

B737_1912

AOI:

AORI_5946

AJA:	AJAP_09695(uox)

AMQ:	AMETH_1603

AMYC:

CU254_07830(pucL) CU254_30640(pucL)

AMYB:

BKN51_23245

AAB:	A4R43_06035 A4R43_18575

AMYY:

YIM_11225(uox1) YIM_19285(uox2)

AORI:

SD37_29145

AACD:

LWP59_08070(pucL)

APRT:

MUY14_26865(pucL)

AROO:

NQK81_36965(pucL)

ATHM:

L1857_10665(pucL) L1857_22270(pucL)

ARHD:

VSH64_27330(pucL) VSH64_47560(pucL)

AMOG:

QRX60_01065(pucL)

ACYN:

ORV05_25065(pucL)

ACOR:

LCL61_14575(pucL)

AMYZ:

HUW46_06349(uox)

ACAB:

QRX50_17500(pucL) QRX50_47070(pucL)

ANW:	QP939_01205(pucL)

AMYD:

K1T34_07965(pucL) K1T34_28100(pucL)

ABAR:

AMYBAR_001577(pucL)

AMYE:

MJQ72_29050(pucL)

AMYS:

CVV72_39580(pucL)

PDX:

Psed_1766

PSEA:

WY02_01130

PSEE:

FRP1_13340

PSEH:

XF36_13125

PSEQ:

AD006_21020

PECQ:

AD017_00600

PHH:	AFB00_24820

PBRO:

HOP40_08910(pucL) HOP40_22150(pucL)

PPEL:

H6H00_24935(pucL)

PSDS:

K1T35_26560(pucL)

APRE:

CNX65_29160(pucL)

AMI:

Amir_5939

SESP:

BN6_71160(uox)

SSYI:

EKG83_39890(pucL)

SACX:

IOD16_29535(pucL)

KAL:

KALB_4480

KUT:	JJ691_27640

KBR:	Q4V65_00230(pucL)

KPHY:

AOZ06_19875

LED:	BBK82_21895

ALO:

CRK55966

PMAD:

BAY61_06850

SACE:

GIY23_11935(pucL)

ACTU:

Actkin_01818(uox)

CROS:

N8J89_32090(pucL)

UME:	RM788_16905(pucL)

MCAB:

HXZ27_12115(pucL)

AMS:	AMIS_63790

ACTN:

L083_6156

AIH:	Aiant_23910

ACTR:

Asp14428_70580

ACTL:

L3i22_088930

ASIC:

Q0Z83_106200(pucL)

AOU:	ACTOB_006889(pucL)

ACTE:

ACTI_03990

AFS:

AFR_31535

PLAB:

C6361_23935(pucL)

PLAT:

C6W10_32815(pucL)

PFLA:

Pflav_051020

PSUU:

Psuf_008750

ATL:	Athai_18200

ASER:

Asera_56240

CATI:

CS0771_69290

DVC:	Dvina_12145(pucL)

DFU:	Dfulv_11265(pucL)

DROS:

Drose_11010(pucL) Drose_25530(pucL)

DAUR:

Daura_11405(pucL)

DMAT:

Dmats_11725(pucL)

DACT:

KZZ52_11355(pucL)

CCAZ:

COUCH_12645(pucL)

CAI:

Caci_4737

SNA:

Snas_2538

AEY:	CDG81_19595(pucL)

JTL:	M6D93_19090(pucL)

RXY:

Rxyl_2843

RRD:	RradSPS_1305

RUB:	GBA63_15660(pucL)

RMAR:

GBA65_15320(pucL)

BALA:

DSM104299_03333(uao_2)

KBS:	EPA93_23380(pucL)

KBB:	ccbrp13_04030

DRA:

DR_1160

DGE:

Dgeo_2601

DGO:	DGo_PA0216

DPD:	Deipe_0078

DSW:	QR90_03870

DPU:	SU48_09955

DEIN:

DAAJ005_13635(pucL)

DGA:	DEGR_34670

DPH:	EHF33_16910(pucL)

DAH:	DAETH_43800

DAQU:

M8445_15990(pucL)

DTAE:

LAJ19_18565(pucL)

DMB:	E5F05_03685(pucL)

DSC:	ABOD76_10320(pucL)

DEID:

HLB42_04005(pucL)

TRA:

Trad_1503

HJE:	HacjB3_16061

HDO:	MUK72_06530(pucL)

NMO:	Nmlp_3624(pucL1)

HAAD:

MW046_18160(pucL)

HWC:	Hqrw_2223(pucL1)

HVO:	HVO_B0300(pucL1)

HALE:

G3A49_07345(pucL)

HAQ:	DU484_08165(pucL)

HAJ:	DU500_08200(pucL)

HAE:	halTADL_2613

NVR:	FEJ81_21285(pucL)

NOU:	Natoc_3147

» show all

Reference

1 [PMID:13363909]

Authors

HUDSON PB, LONDON M.

Title

Purification and properties of solubilized uricase.

Journal

Biochim Biophys Acta 21:290-8 (1956)
DOI:10.1016/0006-3002(56)90010-5

Reference

2 [PMID:13271340]

Authors

MAHLER HR, HUBSCHER G, BAUM R.

Title

Studies on uricase. I. Preparation, purification, and properties of a cuproprotein.

Journal

J Biol Chem 216:625-41 (1955)

Reference

3 [PMID:13252004]

Authors

ROBBINS KC, BARNETT EL, GRANT NH.

Title

Partial pruficiation of procine liver uricase.

Journal

J Biol Chem 216:27-35 (1955)

Reference

4 [PMID:9709003]

Authors

Kahn K, Tipton PA.

Title

Spectroscopic characterization of intermediates in the urate oxidase reaction.

Journal

Biochemistry 37:11651-9 (1998)
DOI:10.1021/bi980446g

Reference

5 [PMID:9360612]

Authors

Colloc'h N, el Hajji M, Bachet B, L'Hermite G, Schiltz M, Prange T, Castro B, Mornon JP

Title

Crystal structure of the protein drug urate oxidase-inhibitor complex at 2.05 A resolution.

Journal

Nat Struct Biol 4:947-52 (1997)
DOI:10.1038/nsb1197-947

Sequence

[afv:AFLA_007981]

Reference

6 [PMID:12680763]

Authors

Imhoff RD, Power NP, Borrok MJ, Tipton PA.

Title

General base catalysis in the urate oxidase reaction: evidence for a novel Thr-Lys catalytic diad.

Journal

Biochemistry 42:4094-100 (2003)
DOI:10.1021/bi027377x

Other DBs

ExplorEnz - The Enzyme Database:

1.7.3.3

IUBMB Enzyme Nomenclature:

1.7.3.3

ExPASy - ENZYME nomenclature database:

1.7.3.3

UM-BBD (Biocatalysis/Biodegradation Database):

1.7.3.3

BRENDA, the Enzyme Database:

1.7.3.3

CAS:

9002-12-4

DBGET integrated database retrieval system