KEGG   ENZYME: 1.8.2.4Help
Entry
EC 1.8.2.4                  Enzyme                                 

Name
dimethyl sulfide:cytochrome c2 reductase;
Ddh (gene name)
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With a cytochrome as acceptor
BRITE hierarchy
Sysname
dimethyl sulfide:cytochrome-c2 oxidoreductase
Reaction(IUBMB)
dimethyl sulfide + 2 ferricytochrome c2 + H2O = dimethyl sulfoxide + 2 ferrocytochrome c2 + 2 H+ [RN:R09500]
Reaction(KEGG)
Substrate
dimethyl sulfide [CPD:C00580];
ferricytochrome c2 [CPD:C00997];
H2O [CPD:C00001]
Product
dimethyl sulfoxide [CPD:C11143];
ferrocytochrome c2 [CPD:C01000];
H+ [CPD:C00080]
Comment
The enzyme from the bacterium Rhodovulum sulfidophilum binds molybdopterin guanine dinucleotide, heme b and [4Fe-4S] clusters.
History
EC 1.8.2.4 created 2011
Pathway
ec00920  Sulfur metabolism
Orthology
K16964  dimethylsulfide dehydrogenase subunit alpha
Genes
RSU: NHU_00476
Taxonomy
Reference
1  [PMID:8706745]
  Authors
Hanlon SP, Toh TH, Solomon PS, Holt RA, McEwan AG
  Title
Dimethylsulfide:acceptor oxidoreductase from Rhodobacter sulfidophilus. The purified enzyme contains b-type haem and a pterin molybdenum cofactor.
  Journal
Eur J Biochem 239:391-6 (1996)
DOI:10.1111/j.1432-1033.1996.0391u.x
  Sequence
Reference
2  [PMID:12067345]
  Authors
McDevitt CA, Hugenholtz P, Hanson GR, McEwan AG
  Title
Molecular analysis of dimethyl sulphide dehydrogenase from Rhodovulum sulfidophilum: its place in the dimethyl sulphoxide reductase family of microbial molybdopterin-containing enzymes.
  Journal
Mol Microbiol 44:1575-87 (2002)
DOI:10.1046/j.1365-2958.2002.02978.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.8.2.4
IUBMB Enzyme Nomenclature: 1.8.2.4
ExPASy - ENZYME nomenclature database: 1.8.2.4
BRENDA, the Enzyme Database: 1.8.2.4

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