KEGG   ENZYME: 1.8.99.2Help
Entry
EC 1.8.99.2                 Enzyme                                 

Name
adenylyl-sulfate reductase;
adenosine phosphosulfate reductase;
adenosine 5'-phosphosulfate reductase;
APS-reductase;
APS reductase;
AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With unknown physiological acceptors
BRITE hierarchy
Sysname
AMP,sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)
Reaction(IUBMB)
AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor [RN:R00860]
Reaction(KEGG)
R00860 > R08553;
(other) R04927
Show
Substrate
AMP [CPD:C00020];
sulfite [CPD:C00094];
acceptor [CPD:C00028]
Product
adenylyl sulfate [CPD:C00224];
reduced acceptor [CPD:C00030]
Comment
An iron flavoprotein (FAD). Methylviologen can act as acceptor.
History
EC 1.8.99.2 created 1972
Pathway
ec00920  Sulfur metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00394  adenylylsulfate reductase, subunit A
K00395  adenylylsulfate reductase, subunit B
Genes
TIG: THII_3105 THII_3106
ALV: Alvin_1120 Alvin_1121
TVI: Thivi_3299 Thivi_3300
TMB: Thimo_1219 Thimo_1220
TSY: THSYN_16395 THSYN_16400
TGR: Tgr7_0350 Tgr7_0351
TKM: TK90_0064 TK90_0065
TNI: TVNIR_3611 TVNIR_3612
TTI: THITH_01410 THITH_01415
SLIM: SCL_0600 SCL_0601 SCL_2473 SCL_2474
ACII: C4901_07620(aprA) C4901_07625(aprB) C4901_14675(aprB) C4901_14680(aprA)
VOK: COSY_0091(aprB) COSY_0092(aprA)
EBH: BSEPE_0126(aprB) BSEPE_0127(aprA)
ENM: EBS_2148(aprA) EBS_2149(aprB)
SHD: SUTH_02771(aprA) SUTH_02772(aprB)
SDR: SCD_n01726(aprB) SCD_n01727(aprA)
DVU: DVU0846(aprB) DVU0847(aprA)
DMA: DMR_05390(aprB) DMR_05400(aprA) DMR_29670
DGG: DGI_0457(aprA) DGI_0458(aprB)
DEF: CNY67_01435(aprB) CNY67_01440(aprA)
DTR: RSDT_0365(aprA) RSDT_0366(aprB)
DPI: BN4_11809(aprA) BN4_11810(aprB)
PPRF: DPRO_2420(aprB) DPRO_2421(aprA)
DRT: Dret_1966(aprA) Dret_1967(aprB)
DML: Dmul_31450(aprA) Dmul_31460(aprB)
DAT: HRM2_04510(aprA) HRM2_04520(aprB)
DTO: TOL2_C04460(aprA) TOL2_C04470(aprB)
PUB: SAR11_0836(aprB) SAR11_0837(aprA)
CAE: SMB_G0105(frdA) SMB_G0106
CKL: CKL_1797 CKL_1798(aprA)
HSC: HVS_02765(nadB1) HVS_02770
PTH: PTH_0239(SdhA) PTH_0240
CHY: CHY_2690(aprB) CHY_2691
KST: KSMBR1_3875(aprB) KSMBR1_3876(apsA)
CTE: CT0864(aspB) CT0865(apsA)
TYE: THEYE_A1832(aprA) THEYE_A1833(aprB)
TTN: TTX_0438(apsA) TTX_0439
 » show all
Taxonomy
Reference
1  [PMID:5421934]
  Authors
Michaels GB, Davidson JT, Peck HD Jr.
  Title
A flavin-sulfite adduct as an intermediate in the reaction catalyzed by adenylyl sulfate reductase from Desulfovibrio vulgaris.
  Journal
Biochem Biophys Res Commun 39:321-8 (1970)
DOI:10.1016/0006-291X(70)90579-6
Other DBs
ExplorEnz - The Enzyme Database: 1.8.99.2
IUBMB Enzyme Nomenclature: 1.8.99.2
ExPASy - ENZYME nomenclature database: 1.8.99.2
BRENDA, the Enzyme Database: 1.8.99.2
CAS: 9027-75-2

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