KEGG   ENZYME: 2.1.1.1Help
Entry
EC 2.1.1.1                  Enzyme                                 

Name
nicotinamide N-methyltransferase;
nicotinamide methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:nicotinamide N-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-methylnicotinamide [RN:R01269]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
nicotinamide [CPD:C00153]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
1-methylnicotinamide [CPD:C02918]
History
EC 2.1.1.1 created 1961
Pathway
ec00760  Nicotinate and nicotinamide metabolism
ec01100  Metabolic pathways
Orthology
K00541  nicotinamide N-methyltransferase
Genes
HSA: 4837(NNMT)
PTR: 451558(NNMT)
PPS: 100986024(NNMT)
GGO: 101125265(NNMT)
PON: 100448230(NNMT)
NLE: 100592910(NNMT)
MCC: 695185(NNMT)
MCF: 102127301(NNMT)
CSAB: 103248504(NNMT)
RRO: 104669403(NNMT)
RBB: 108536424(NNMT)
CJC: 100406861(NNMT)
SBQ: 101045951(NNMT)
MMU: 18113(Nnmt)
RNO: 300691(Nnmt)
CGE: 100767696(Nnmt)
NGI: 103729026(Nnmt)
HGL: 101716424(Nnmt)
CCAN: 109696853(Nnmt)
TUP: 102502244(NNMT) 106735122
AML: 100476505(NNMT)
UMR: 103662369(NNMT)
ORO: 101365581(NNMT) 101377589
PHD: 102324461
CHX: 102180514(NNMT)
OAS: 101111049
SSC: 100144485(NNMT)
CFR: 102513656(NNMT)
CDK: 105091729(NNMT)
LVE: 103089764
OOR: 101288581
ECB: 100070808(NNMT)
EAI: 106840236(NNMT)
MYB: 102252520(NNMT)
MYD: 102769607(NNMT)
HAI: 109376323(NNMT)
RSS: 109459117(NNMT)
PALE: 102893498(NNMT)
LAV: 100673708(NNMT)
TMU: 101359298
MDO: 100032114(NNMT)
OAA: 100080750(NNMT) 100080807
CCW: 104692167(NNMT)
FPG: 101913616(NNMT)
FCH: 102055024(NNMT)
CLV: 102085200(NNMT)
EGZ: 104133392
AMJ: 102560500 102572902(NNMT)
DRE: 393330(zgc:64002)
SRX: 107739813
SANH: 107700100
SGH: 107588841
CCAR: 109093888
IPU: 108258972
AMEX: 103032094
SASA: 100286563(nnmt)
ELS: 105011159
SFM: 108941486
CEL: CELE_B0303.2(anmt-1)
CBR: CBG00588
BMY: Bm1_41455
TSP: Tsp_04293
 » show all
Taxonomy
Reference
1  [PMID:14832232]
  Authors
CANTONI GL.
  Title
Methylation of nicotinamide with soluble enzyme system from rat liver.
  Journal
J Biol Chem 189:203-16 (1951)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.1
IUBMB Enzyme Nomenclature: 2.1.1.1
ExPASy - ENZYME nomenclature database: 2.1.1.1
BRENDA, the Enzyme Database: 2.1.1.1
CAS: 9029-74-7

DBGET integrated database retrieval system