KEGG   ENZYME: 2.1.1.109Help
Entry
EC 2.1.1.109                Enzyme                                 

Name
demethylsterigmatocystin 6-O-methyltransferase;
demethylsterigmatocystin methyltransferase;
O-methyltransferase I
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 6-demethylsterigmatocystin = S-adenosyl-L-homocysteine + sterigmatocystin [RN:R03112]
Reaction(KEGG)
R03112;
(other) R10403
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Substrate
S-adenosyl-L-methionine [CPD:C00019];
6-demethylsterigmatocystin [CPD:C03683]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
sterigmatocystin [CPD:C00961]
Comment
Dihydrodemethylsterigmatocystin can also act as acceptor. Involved in the biosynthesis of aflatoxins in fungi.
History
EC 2.1.1.109 created 1992
Pathway
ec00254  Aflatoxin biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K17649  demethylsterigmatocystin 6-O-methyltransferase
Genes
PAN: PODANSg8572
AOR: AO090026000025
ANG: ANI_1_2158014(An01g00880)
AFV: AFLA_139220
PCS: Pc18g03140
URE: UREG_07660
PNO: SNOG_08160
Taxonomy
Reference
1  [PMID:2802602]
  Authors
Yabe K, Ando Y, Hashimoto J, Hamasaki T.
  Title
Two distinct O-methyltransferases in aflatoxin biosynthesis.
  Journal
Appl Environ Microbiol 55:2172-7 (1989)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.109
IUBMB Enzyme Nomenclature: 2.1.1.109
ExPASy - ENZYME nomenclature database: 2.1.1.109
BRENDA, the Enzyme Database: 2.1.1.109
CAS: 123516-47-2

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