KEGG   ENZYME: 2.1.1.121Help
Entry
EC 2.1.1.121                Enzyme                                 

Name
6-O-methylnorlaudanosoline 5'-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline [RN:R04714]
Reaction(KEGG)
R04714;
(other) R05213
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Substrate
S-adenosyl-L-methionine [CPD:C00019];
6-O-methylnorlaudanosoline [CPD:C05203]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
nororientaline [CPD:C05317]
Comment
Nororientaline is a precursor of the alkaloid papaverine.
History
EC 2.1.1.121 created 1999
Pathway
ec00950  Isoquinoline alkaloid biosynthesis
Reference
1  [PMID:17405051]
  Authors
Rueffer M, Nagakura N, Zenk MH
  Title
A Highly Specific O-Methyltransferase for Nororientaline Synthesis Isolated from  Argemone platyceras Cell Cultures.
  Journal
Planta Med 49:196-8 (1983)
DOI:10.1055/s-2007-969849
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.121
IUBMB Enzyme Nomenclature: 2.1.1.121
ExPASy - ENZYME nomenclature database: 2.1.1.121
BRENDA, the Enzyme Database: 2.1.1.121
CAS: 89511-99-9

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