KEGG   ENZYME: 2.1.1.174Help
Entry
EC 2.1.1.174                Enzyme                                 

Name
23S rRNA (guanine1835-N2)-methyltransferase;
ygjO (gene name);
rlmG (gene name);
ribosomal RNA large subunit methyltransferase G
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:23S rRNA (guanine1835-N2)-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + guanine1835 in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA [RN:R07234]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
guanine1835 in 23S rRNA
Product
S-adenosyl-L-homocysteine [CPD:C00021];
N2-methylguanine1835 in 23S rRNA
Comment
The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [1]. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA.
History
EC 2.1.1.174 created 1976 as EC 2.1.1.52, part transferred 2010 to EC 2.1.1.174
Orthology
K11391  23S rRNA (guanine1835-N2)-methyltransferase
Genes
ECO: b3084(rlmG)
ECJ: JW5513(ygjO)
ECD: ECDH10B_3259(ygjO)
EBW: BWG_2794(rlmG)
ECOK: ECMDS42_2553(ygjO)
ECE: Z4437(ygjO)
ECS: ECs3966
ECF: ECH74115_4398
ETW: ECSP_4058(ygjO)
ELX: CDCO157_3707
EOJ: ECO26_4186(ygjO)
EOI: ECO111_3906(ygjO)
EOH: ECO103_3829(ygjO)
ECOO: ECRM13514_4046(ygjO)
ECOH: ECRM13516_3849(ygjO)
ECG: E2348C_3376(rlmG)
EOK: G2583_3808(rlmG)
ESO: O3O_22110
ESM: O3M_03575
ESL: O3K_03535
ELH: ETEC_3354
ECC: c3842(ygjO)
ECP: ECP_3175
ECI: UTI89_C3522(ygjO)
ECV: APECO1_3334(ygjO)
ECY: ECSE_3364
ECR: ECIAI1_3230(ygjO)
ECQ: ECED1_3751(ygjO)
ECK: EC55989_3498(ygjO)
ECT: ECIAI39_3580(ygjO)
EOC: CE10_3613(rlmG)
EUM: ECUMN_3567(ygjO)
ECZ: ECS88_3479(ygjO)
ESE: ECSF_2927
EBR: ECB_02953(ygjO)
EBD: ECBD_0658
EKF: KO11_07285(rlmG)
EAB: ECABU_c35030(ygjO)
EDJ: ECDH1ME8569_2979(rlmG)
ELW: ECW_m3350(rlmG)
ELL: WFL_16375(rlmG)
ELC: i14_3533(ygjO)
ELD: i02_3533(ygjO)
ELP: P12B_c3200(ygjO)
EBL: ECD_02953(rlmG)
EBE: B21_02903(rlmG)
ELF: LF82_1893(rlmG)
ECOI: ECOPMV1_03400(rlmG)
ECOJ: P423_17415
ECOS: EC958_3490(ygjO)
EFE: EFER_4394(ygjO)
STY: STY3400(ygjO)
STT: t3140(ygjO)
STM: STM3220(ygjO)
SEO: STM14_3899(ygjO)
SEY: SL1344_3193(ygjO)
SEJ: STMUK_3209(ygjO)
SEB: STM474_3374(ygjO)
SENR: STMDT2_31131(ygjO)
SEND: DT104_32161(ygjO)
SENI: CY43_16785
SPT: SPA3088(ygjO)
SEK: SSPA2884
SEI: SPC_3296(ygjO)
SEC: SCH_3167(ygjO)
SHB: SU5_03715
SENS: Q786_15705
SED: SeD_A3577
SEG: SG3116(ygjO)
SEL: SPUL_3233
SET: SEN3062(ygjO)
SENA: AU38_15585
SENO: AU37_15785
SENV: AU39_15785
SENQ: AU40_17565
SENL: IY59_16190
SEEP: I137_15425
SENB: BN855_33000(ygjO)
SENE: IA1_15575
SBG: SBG_2855(ygjO)
SBZ: A464_3299
SFL: SF3124(ygjO)
SFX: S3331(ygjO)
SFV: SFV_3126(ygjO)
SFE: SFxv_3432
SFN: SFy_4463
SFS: SFyv_4540
SFT: NCTC1_03388(ygjO)
SSN: SSON_3121(ygjO)
SBO: SBO_2945(ygjO)
SDY: SDY_3267(ygjO)
ENC: ECL_04486
ECLO: ENC_33430
EEC: EcWSU1_03902(rlmG)
ECLX: LI66_19550
ECLY: LI62_21550
ECLZ: LI64_18690
ENF: AKI40_0663(ygjO)
ESA: ESA_03495
CSK: ES15_3451
CTU: CTU_04720(rlmG)
KPN: KPN_03511(ygjO)
KPU: KP1_4809(ygjO)
KPP: A79E_0606
KPT: VK055_3957(rlmG)
KPE: KPK_0601
KPR: KPR_4715(rlmG)
KPJ: N559_0660
KPX: PMK1_01029(rlmG)
KPNU: LI86_03195
KPNK: BN49_0596(rlmG)
KVA: Kvar_0589
KOX: KOX_03330
KOE: A225_5114
EAE: EAE_03970
EAR: CCG33198
CKO: CKO_04488
CRO: ROD_48031
CAMA: F384_17010
EBT: EBL_c04680(ygjO)
EBF: D782_0605
YPE: YPO0588
YPK: y3590
YPH: YPC_3992(ygjO)
YPA: YPA_3200
YPN: YPN_0457
YPM: YP_2908(rsmC1)
YPZ: YPZ3_0564
YPD: YPD4_0516
YPX: YPD8_0518
YPW: CH59_1275
YPJ: CH55_2223
YPV: BZ15_2985
YPL: CH46_328
YPS: YPTB3470
YPO: BZ17_3132
YPY: YPK_0562
YPB: YPTS_3655
YPQ: DJ40_2950(rlmG)
YPU: BZ21_2793
YPR: BZ20_2647
YPC: BZ23_3066
YPF: BZ19_2929
YEN: YE3699
YEY: Y11_25731
YEW: CH47_4100(rlmG)
YET: CH48_2219
YAL: AT01_1978
YFR: AW19_2701(rlmG)
YIN: CH53_2310
YKR: CH54_3087
YRO: CH64_2128
YRU: BD65_1458
SPE: Spro_4312
SRL: SOD_c41180(rlmG)
SPLY: Q5A_022470(rlmG)
SMAF: D781_4038
SMW: SMWW4_v1c42740(rlmG)
SMAR: SM39_3767(rlmG)
SMAC: SMDB11_3549(rlmG)
SERF: L085_06845
RAA: Q7S_02625
ECA: ECA0654
PATR: EV46_02865
PATO: GZ59_05720
PCT: PC1_0536
PEC: W5S_0651
SOD: Sant_3645(ygjO)
DDD: Dda3937_03553(rlmG)
DDQ: DDI_0362
ETA: ETA_28960(rsmD)
EPY: EpC_05660(rsmD)
EPR: EPYR_00589(ygjO)
EAM: EAMY_3090(ygjO)
EAY: EAM_0506(ygjO)
EBI: EbC_05240(rsmD)
ERJ: EJP617_05360(rsmD)
EGE: EM595_3026(rlmG)
PAM: PANA_3449(ygjO)
PLF: PANA5342_0604(ygjO)
PAJ: PAJ_2682(ygjO)
PVA: Pvag_2718(ygjO)
PSTW: DSJ_21130
TPTY: NCTC11468_03217(rlmG)
ETR: ETAE_0445(rsmC1)
ETD: ETAF_0398(rlmG)
ETE: ETEE_2205(rlmG)
LRI: NCTC12151_02055(rlmG)
PSHI: SAMEA2665130_1691(rlmG)
VCH: VC2297
VCS: MS6_2041
VCI: O3Y_11050
VVU: VV1_1819
VVY: VV2592
VVL: VV93_v1c23100(rlmG)
VPA: VP2353
VPB: VPBB_2183
VAG: N646_1470
VSP: VS_0691
VNI: VIBNI_A0563(rlmG)
VAN: VAA_03618
VAU: VANGNB10_cI2083(rlmG)
VTA: A1489(rlmG)
VFI: VF_0723(rlmG)
AWD: AWOD_I_0694(rlmG)
PPR: PBPRA0819(YGJO)
PAE: PA4617
PAEV: N297_4770
PAEI: N296_4770
PAEP: PA1S_25025
PAEM: U769_25280
PAEL: T223_25545
PAEG: AI22_09020
PAEC: M802_4768
PAEO: M801_4635
PMY: Pmen_0751
PMK: MDS_0856
PRE: PCA10_08870(rlmG)
PPSE: BN5_0635
PCQ: PcP3B5_54980(rlmG)
PPU: PP_4648(rlmG)
PPF: Pput_4510
PPT: PPS_4478
PPI: YSA_03235
PPX: T1E_0822
PPUH: B479_22520
PPUT: L483_27735
PPUN: PP4_07090(rlmG)
PPUD: DW66_4870
PMON: X969_22060
PMOT: X970_21695
PSB: Psyr_4279
PSYR: N018_22275
PFL: PFL_5361(rlmG)
PPRC: PFLCHA0_c53340(rlmG)
PPRO: PPC_5336
PFS: PFLU_5343
PFE: PSF113_5079(rsmC)
PFC: PflA506_4637(rlmG)
PFW: PF1751_v1c47630(rlmG)
PFB: VO64_2181
PMAN: OU5_4294(rlmG)
PEN: PSEEN4774
PSA: PST_0932
PSTT: CH92_03585
PPUU: PputUW4_04708(rsmC2)
PKC: PKB_5093(rlmG)
PSES: PSCI_1055
PSEM: TO66_27245
PSEC: CCOS191_4661(rlmG)
PSOS: POS17_5324
PANR: A7J50_5066
PSET: THL1_935
PSIL: PMA3_03025
SON: SO_1097(rlmG)
SDN: Sden_2937
SBL: Sbal_0918
SLO: Shew_2886
SSE: Ssed_3436
SPL: Spea_3107
SHL: Shal_3191
SWD: Swoo_3625
SWP: swp_1161
SVO: SVI_3344
SPSW: Sps_04310
CPS: CPS_0711
PHA: PSHAa2245(rsmD)
PAT: Patl_0447
PSM: PSM_A0841(rsmD)
PSEO: OM33_14430
PTN: PTRA_a2721(rsmC)
PEA: PESP_a1046(rsmC)
PSPO: PSPO_a2433(rsmC)
PART: PARC_a2994(rsmC)
PTU: PTUN_a3300(rsmC)
PNG: PNIG_a2917(rsmC)
PTD: PTET_a0954(rsmC)
PSEN: PNC201_13590(rlmG)
MAQ: Maqu_1941
MHC: MARHY1364
MAD: HP15_2265
MBS: MRBBS_1051(rlmG)
AMAL: I607_03165
AMAE: I876_03375
AMAO: I634_03480
AMAD: I636_03265
AMAI: I635_03245
AMAG: I533_03145
AMAC: MASE_02720
AAUS: EP12_03335
GNI: GNIT_2849(rsmC)
PIN: Ping_2296
FBL: Fbal_0889
MVS: MVIS_0600(rlmG)
MYA: MORIYA_2371(ygjO)
SAGA: M5M_14005
MAH: MEALZ_1825(rlmG)
GAI: IMCC3135_12830(rlmG)
ABO: ABO_1448(rsmC)
ADI: B5T_02224(rsmC)
APAC: S7S_09680
AXE: P40_10720
TOL: TOL_1815
OAI: OLEAN_C18060(rsmC1)
RFO: REIFOR_01679(rlmG)
OME: OLMES_0408(rlmG)
AHA: AHA_1134
ASA: ASA_3201
AVR: B565_3093
AMED: B224_4122
ASR: WL1483_1323(rlmG)
ACAV: VI35_15745
TAU: Tola_0799
OCE: GU3_05950
TBN: TBH_C0036
PLG: NCTC10937_00913(rlmG)
BMX: BMS_0941
MGM: Mmc1_2217
SCO: SCO1041(SCG20A.21)
SMA: SAVERM_1444(rsmC)
SGR: SGR_6774
SGB: WQO_01160
SFA: Sfla_6003
SHY: SHJG_2506
SVE: SVEN_1178
SDV: BN159_7890(rlmG)
SALS: SLNWT_7183
STRP: F750_0566(rlmG)
SFI: SFUL_354
SLV: SLIV_32585(rlmG)
SGU: SGLAU_03790(rlmG)
STRM: M444_29675
SAMB: SAM23877_1131(rlmG)
SPRI: SPRI_6233
SRW: TUE45_01404(rlmG)
SLE: sle_60630(sle_60630)
SRN: A4G23_00830(rlmG)
STRD: NI25_33970
SLAU: SLA_1105
SALF: SMD44_00821(rsmC)
SALJ: SMD11_6499(rsmC)
SLX: SLAV_05990(rlmG)
SFK: KY5_0828c
KSK: KSE_15060
SRO: Sros_3489
CAI: Caci_5405
MBAS: ALGA_0676
SGN: SGRA_4031
TMAR: MARIT_0984
 » show all
Taxonomy
Reference
1  [PMID:17010380]
  Authors
Sergiev PV, Lesnyak DV, Bogdanov AA, Dontsova OA
  Title
Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA.
  Journal
J Mol Biol 364:26-31 (2006)
DOI:10.1016/j.jmb.2006.09.008
  Sequence
[eco:b3084]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.174
IUBMB Enzyme Nomenclature: 2.1.1.174
ExPASy - ENZYME nomenclature database: 2.1.1.174
BRENDA, the Enzyme Database: 2.1.1.174

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