KEGG   ENZYME: 2.1.1.210Help
Entry
EC 2.1.1.210                Enzyme                                 

Name
demethylspheroidene O-methyltransferase;
1-hydroxycarotenoid O-methylase;
1-hydroxycarotenoid methylase;
1-HO-carotenoid methylase;
CrtF
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + demethylspheroidene = S-adenosyl-L-homocysteine + spheroidene [RN:R07535]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
demethylspheroidene [CPD:C15898]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
spheroidene [CPD:C15900]
Comment
In Rhodopseudomonas capsulata and Rubrivivax gelatinosus the enzyme is involved in biosynthesis of spheroidene [1,2,3]. In Rubrivivax gelatinosus the enzyme also catalyses the methylation of demethylspirilloxanthin to spirilloxanthin and the methylation of 3,4-didehydrorhodopin to anhydrorhodovibrin [2].
History
EC 2.1.1.210 created 2011
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09846  demethylspheroidene O-methyltransferase
Genes
ALV: Alvin_2564
TVI: Thivi_2013
TMB: Thimo_3007
MPUR: MARPU_13360
TSY: THSYN_31020
HHA: Hhal_1612
HHC: M911_10360
EBS: ECTOBSL9_3048
PDQ: CL55_00013610
RAC: RA876_05990
LIM: L103DPR2_00970(crtF)
LIH: L63ED372_00626(crtF)
RGE: RGE_33720(crtF)
BRA: BRADO1616(crtF)
BBT: BBta_6439(crtF)
BRS: S23_19160(crtF)
AOL: S58_59200
BRO: BRAD285_5783(crtF)
RPA: RPA1520(crtF)
RPB: RPB_4003
RPC: RPC_1291
RPD: RPD_3758
RPE: RPE_1325
RPT: Rpal_1708
MEX: Mext_2728
MEA: Mex_1p2925(crtF)
MDI: METDI3494(crtF)
MCH: Mchl_2955
MPO: Mpop_2850
MET: M446_3695
MOR: MOC_3185
META: Y590_13130
MSL: Msil_2050
RVA: Rvan_0208
MSC: BN69_3625
RSP: RSP_0264(crtF)
RCP: RCAP_rcc00685(crtF)
JAN: Jann_0181(crtF)
RDE: RD1_0113(crtF)
RLI: RLO149_p940140(crtF)
DSH: Dshi_3515(crtF)
PTP: RCA23_c29600(crtF)
RSU: NHU_04285
RHC: RGUI_1963
RMM: ROSMUCSMR3_00907(crtF)
LVS: LOKVESSMR4R_03677(crtF)
SPHI: TS85_22895
SSAN: NX02_18460
BLAS: BSY18_3553
AMV: ACMV_18810(crtF)
RRU: Rru_A2982
RRF: F11_15275
RCE: RC1_2092(crtF)
RPM: RSPPHO_01502(crtF)
 » show all
Taxonomy
Reference
1  [PMID:12770713]
  Authors
Badenhop F, Steiger S, Sandmann M, Sandmann G
  Title
Expression and biochemical characterization of the 1-HO-carotenoid methylase CrtF from Rhodobacter capsulatus.
  Journal
FEMS Microbiol Lett 222:237-42 (2003)
DOI:10.1016/S0378-1097(03)00302-1
  Sequence
Reference
2  [PMID:12664193]
  Authors
Pinta V, Ouchane S, Picaud M, Takaichi S, Astier C, Reiss-Husson F.
  Title
Characterization of unusual hydroxy- and ketocarotenoids in Rubrivivax gelatinosus: involvement of enzyme CrtF or CrtA.
  Journal
Arch Microbiol 179:354-62 (2003)
DOI:10.1007/s00203-003-0538-3
  Sequence
[rge:RGE_33720]
Reference
3  [PMID:7358679]
  Authors
Scolnik PA, Walker MA, Marrs BL
  Title
Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata.
  Journal
J Biol Chem 255:2427-32 (1980)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.210
IUBMB Enzyme Nomenclature: 2.1.1.210
ExPASy - ENZYME nomenclature database: 2.1.1.210
BRENDA, the Enzyme Database: 2.1.1.210

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