KEGG   ENZYME: 2.1.1.240Help
Entry
EC 2.1.1.240                Enzyme                                 

Name
trans-resveratrol di-O-methyltransferase;
ROMT;
resveratrol O-methyltransferase;
pterostilbene synthase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Reaction(IUBMB)
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];
(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];
(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
trans-resveratrol [CPD:C03582];
3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
pterostilbene [CPD:C10287];
3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Comment
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
History
EC 2.1.1.240 created 2012
Pathway
ec00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
Orthology
K16040  trans-resveratrol di-O-methyltransferase
Genes
CPAP: 110815070
CIT: 102619265 102625421 112496217
CIC: CICLE_v10015708mg
TCC: 18608792
GRA: 105778115
GHI: 107915911
DZI: 111309887
EGR: 104429802 104441099
GMX: 100781008 100808134 102669052
PVU: PHAVU_008G1678000 PHAVU_008G250600g PHAVU_011G118100g PHAVU_011G1222001
CCAJ: 109805860
CAM: 101506695
LJA: Lj2g3v2378050.1(Lj2g3v2378050.1)
ADU: 107458207
LANG: 109339247
FVE: 101312070
ZJU: 107417276
CSV: 101216522
MCHA: 111007572
CMOS: 111455045
RCU: 8285028
NTO: 104097284
OEU: 111392924
DCR: 108194686
BVG: 104903610
SOE: 110786811
OSA: 107276038
DOSA: Os01t0753300-00(Os01g0753300) Os07t0462800-00(Os07g0462800) Os11t0304050-00(Os11g0304050) Os11t0305400-00(Os11g0305400) Os11t0306300-01(Os11g0306300)
ATS: 109736023(LOC109736023) 109737732(LOC109737732) 109760740(LOC109760740)
MUS: 103983314
AOF: 109825636
ATR: 18448090
 » show all
Taxonomy
Reference
1  [PMID:18799660]
  Authors
Schmidlin L, Poutaraud A, Claudel P, Mestre P, Prado E, Santos-Rosa M, Wiedemann-Merdinoglu S, Karst F, Merdinoglu D, Hugueney P
  Title
A stress-inducible resveratrol O-methyltransferase involved in the biosynthesis of pterostilbene in grapevine.
  Journal
Plant Physiol 148:1630-9 (2008)
DOI:10.1104/pp.108.126003
  Sequence
[vvi:100233030]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.240
IUBMB Enzyme Nomenclature: 2.1.1.240
ExPASy - ENZYME nomenclature database: 2.1.1.240
BRENDA, the Enzyme Database: 2.1.1.240

DBGET integrated database retrieval system