KEGG   ENZYME: 2.1.1.27Help
Entry
EC 2.1.1.27                 Enzyme                                 

Name
tyramine N-methyltransferase;
DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid);
S-adenosyl-methionine:tyramine N-methyltransferase;
tyramine methylpherase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:tyramine N-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + tyramine = S-adenosyl-L-homocysteine + N-methyltyramine [RN:R02384]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
tyramine [CPD:C00483]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
N-methyltyramine [CPD:C02442]
Comment
Has some activity on phenylethylamine analogues.
History
EC 2.1.1.27 created 1972
Pathway
ec00350  Tyrosine metabolism
Reference
1
  Authors
Mann, J.D. and Mudd, S.H.
  Title
Alkaloids and plant metabolism. IV. The tyramine methylpherase of barley roots.
  Journal
J Biol Chem 238:381-385 (1963)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.27
IUBMB Enzyme Nomenclature: 2.1.1.27
ExPASy - ENZYME nomenclature database: 2.1.1.27
BRENDA, the Enzyme Database: 2.1.1.27
CAS: 37256-96-5

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