KEGG   ENZYME: 2.1.1.3Help
Entry
EC 2.1.1.3                  Enzyme                                 

Name
thetin---homocysteine S-methyltransferase;
dimethylthetin-homocysteine methyltransferase;
thetin-homocysteine methylpherase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
dimethylsulfonioacetate:L-homocysteine S-methyltransferase
Reaction(IUBMB)
dimethylsulfonioacetate + L-homocysteine = S-methylthioglycolate + L-methionine [RN:R04153]
Reaction(KEGG)
Substrate
dimethylsulfonioacetate [CPD:C03392];
L-homocysteine [CPD:C00155]
Product
S-methylthioglycolate [CPD:C03173];
L-methionine [CPD:C00073]
History
EC 2.1.1.3 created 1961
Reference
1  [PMID:14456704]
  Authors
KLEE WA, RICHARDS HH, CANTONI GL.
  Title
The synthesis of methionine by enzymic transmethylation. VII. Existence of two separate homocysteine methylpherases on mammalian liver.
  Journal
Biochim Biophys Acta 54:157-64 (1961)
DOI:10.1016/0006-3002(61)90948-9
Reference
2  [PMID:13315256]
  Authors
MAW GA.
  Title
Thetin-homocysteine transmethylase; a preliminary manometric study of the enzyme from rat liver.
  Journal
Biochem J 63:116-24 (1956)
Reference
3  [PMID:13584318]
  Authors
MAW GA.
  Title
Thetin-homocysteine transmethylase; some further characteristics of the enzyme from rat liver.
  Journal
Biochem J 70:168-73 (1958)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.3
IUBMB Enzyme Nomenclature: 2.1.1.3
ExPASy - ENZYME nomenclature database: 2.1.1.3
BRENDA, the Enzyme Database: 2.1.1.3
CAS: 9029-76-9

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