KEGG   ENZYME: 2.2.1.3Help
Entry
EC 2.2.1.3                  Enzyme                                 

Name
formaldehyde transketolase;
dihydroxyacetone synthase
Class
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
BRITE hierarchy
Sysname
D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase
Reaction(IUBMB)
D-xylulose 5-phosphate + formaldehyde = D-glyceraldehyde 3-phosphate + glycerone [RN:R01440]
Reaction(KEGG)
R01440;
(other) R06861 R06862
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Substrate
D-xylulose 5-phosphate [CPD:C00231];
formaldehyde [CPD:C00067]
Product
D-glyceraldehyde 3-phosphate [CPD:C00118];
glycerone [CPD:C00184]
Comment
A thiamine-diphosphate protein. Not identical with EC 2.2.1.1 transketolase. Also converts hydroxypyruvate and formaldehyde into glycerone and CO2.
History
EC 2.2.1.3 created 1984
Pathway
ec00680  Methane metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K17100  dihydroxyacetone synthase
Genes
PPA: PAS_chr3_0832 PAS_chr3_0834
DHA: DEHA2B00616g DEHA2F00968g
PIC: PICST_53327(DHA1)
PGU: PGUG_01217
CTEN: CANTEDRAFT_131235
SLB: AWJ20_4479(TKL1)
MGR: MGG_09856
TMN: UCRPA7_3396 UCRPA7_4269
FGR: FGSG_04065
FPU: FPSE_05207
ANG: ANI_1_510124(An14g03500)
PTE: PTT_19509
 » show all
Taxonomy
Reference
1  [PMID:7249920]
  Authors
Bystrykh LV, Sokolov AP, Trotsenko IuA.
  Title
[Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts]
  Journal
Dokl Akad Nauk SSSR 258:499-501 (1981)
Reference
2  [PMID:7074134]
  Authors
Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H.
  Title
Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, candida boidinii (Kloeckera sp.) No. 2201.
  Journal
Biochim Biophys Acta 715:143-50 (1982)
DOI:10.1016/0304-4165(82)90352-X
Reference
3  [PMID:6276498]
  Authors
Waites MJ, Quayle JR.
  Title
The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii.
  Journal
J Gen Microbiol 124:309-16 (1981)
DOI:10.1099/00221287-124-2-309
Other DBs
ExplorEnz - The Enzyme Database: 2.2.1.3
IUBMB Enzyme Nomenclature: 2.2.1.3
ExPASy - ENZYME nomenclature database: 2.2.1.3
BRENDA, the Enzyme Database: 2.2.1.3
CAS: 124566-23-0

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