KEGG   ENZYME: 2.2.1.9Help
Entry
EC 2.2.1.9                  Enzyme                                 

Name
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase;
SEPHCHC synthase;
MenD
Class
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
BRITE hierarchy
Sysname
isochorismate:2-oxoglutarate 4-oxopentanoatetransferase (decarboxylating)
Reaction(IUBMB)
isochorismate + 2-oxoglutarate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2 [RN:R08165]
Reaction(KEGG)
Substrate
isochorismate [CPD:C00885];
2-oxoglutarate [CPD:C00026]
Product
5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate;
CO2 [CPD:C00011]
Comment
Requires Mg2+ for maximal activity. This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the products of the reaction were (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate (SHCHC), pyruvate and CO2 but it is now known that two separate enzymes are involved: this enzyme and EC 4.2.99.20, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. Under basic conditions, the product can spontaneously lose pyruvate to form SHCHC.
History
EC 2.2.1.9 created 2008 (EC 2.5.1.64 created 2003, part-incorporated 2008)
Pathway
ec00130  Ubiquinone and other terpenoid-quinone biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K02551  2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
K14759  isochorismate synthase / 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase / O-succinylbenzoate synthase
Genes
ATH: AT1G68890(PHYLLO)
ALY: ARALYDRAFT_894670
CRB: 17894367
CSAT: 104704752 104750694 104787948 104789721
EUS: EUTSA_v10017999mg
BRP: 103852540
BNA: 106393361 106428528
BOE: 106327192
THJ: 104821983
CPAP: 110820107
CIT: 102608540
TCC: 18610138
GRA: 105794273
DZI: 111318210
EGR: 104453859
GMX: 100798570
VRA: 106761862
VAR: 108334153
CCAJ: 109807754
CAM: 101508711
LJA: Lj0g3v0360399.1(Lj0g3v0360399.1) Lj0g3v0360399.2(Lj0g3v0360399.2) Lj3g3v3654520.1(Lj3g3v3654520.1)
ADU: 107477124
AIP: 107628739
LANG: 109332680
FVE: 101297638
PPER: 18791507
PMUM: 103342087
PAVI: 110757742
MDM: 103425450
PXB: 103946661
ZJU: 107429107
CSV: 101217012
CMO: 103489211
MCHA: 111017565
CMAX: 111488697
CMOS: 111458428
CPEP: 111776726
RCU: 8264631
JCU: 105640708
HBR: 110660726
POP: 7482230
JRE: 108981645
VVI: 100241089
SLY: 101245351
SPEN: 107017693
SOT: 102603926
CANN: 107870618
NSY: 104216590
NTO: 104112285
INI: 109176245
SIND: 105161713
OEU: 111404630
HAN: 110914946
LSV: 111896435
CCAV: 112523262
DCR: 108196102
BVG: 104896273
NNU: 104597836
DOSA: Os02t0581500-01(Os02g0581500)
OBR: 102708030
BDI: 100843372
ATS: 109752118(LOC109752118)
SBI: 8055409
SITA: 101780975
PDA: 103706601
EGU: 105061098
MUS: 103989974
DCT: 110109286
PEQ: 110018366
AOF: 109840254
ATR: 18433994
PPP: 112287061
ECO: b2264(menD)
ECJ: JW5374(menD)
ECD: ECDH10B_2425(menD)
EBW: BWG_2038(menD)
ECOK: ECMDS42_1835(menD)
ECE: Z3524(menD)
ECS: ECs3152
ECF: ECH74115_3406(menD)
ETW: ECSP_3142(menD)
EOJ: ECO26_3255(menD)
EOI: ECO111_3015(menD)
EOH: ECO103_2731(menD)
ECOO: ECRM13514_3021(menD)
ECOH: ECRM13516_2966(menD)
ECG: E2348C_2409(menD)
EOK: G2583_2805(menD)
ESO: O3O_17470
ESM: O3M_08115
ESL: O3K_08165
ECW: EcE24377A_2560(menD)
ELH: ETEC_2399
EUN: UMNK88_2817(menD)
ECC: c2808(menD)
ECP: ECP_2308
ECI: UTI89_C2548(menD)
ECV: APECO1_4297(menD)
ECX: EcHS_A2410(menD)
ECM: EcSMS35_2419(menD)
ECY: ECSE_2524
ECR: ECIAI1_2342(menD)
ECQ: ECED1_2732(menD)
ECK: EC55989_2512(menD)
ECT: ECIAI39_2412(menD)
EOC: CE10_2648(menD)
EUM: ECUMN_2607(menD)
ECZ: ECS88_2415(menD)
ELO: EC042_2508(menD)
ESE: ECSF_2145
EBR: ECB_02191(menD)
EBD: ECBD_1394
EKF: KO11_11360(menD)
EAB: ECABU_c26000(menD)
EDJ: ECDH1ME8569_2201(menD)
EIH: ECOK1_2501(menD)
ENA: ECNA114_2358(menD)
ELW: ECW_m2456(menD)
ELL: WFL_12020(menD)
ELC: i14_2607(menD)
ELD: i02_2607(menD)
ELP: P12B_c2359(menD)
EBL: ECD_02191(menD)
EBE: B21_02150(menD)
ELF: LF82_1313(menD)
ECOI: ECOPMV1_02426(menD)
ECOJ: P423_12675
ECOS: EC958_2603(menD)
EFE: EFER_0904(menD)
EAL: EAKF1_ch3714(menD)
STY: STY2540(menD)
STT: t0554(menD)
STM: STM2309(menD)
SEO: STM14_2847(menD)
SEY: SL1344_2278(menD)
SEJ: STMUK_2339(menD)
SEB: STM474_2405(menD)
SEF: UMN798_2491(menD)
SENR: STMDT2_22781(menD)
SEND: DT104_23671(menD)
SENI: CY43_12370
SPT: SPA0554(menD)
SEK: SSPA0518
SEI: SPC_1402(menD)
SEC: SCH_2309(menD)
SEH: SeHA_C2549(menD)
SHB: SU5_02904
SEE: SNSL254_A2494(menD)
SEW: SeSA_A2537(menD)
SEA: SeAg_B2445(menD)
SENS: Q786_11385
SED: SeD_A2653(menD)
SEG: SG2338(menD)
SEL: SPUL_0581(menD)
SEGA: SPUCDC_0581(menD)
SET: SEN2291(menD)
SENA: AU38_11580
SENO: AU37_11590
SENV: AU39_11590
SENQ: AU40_12970
SENL: IY59_11905
SEEP: I137_02680
SENB: BN855_23900(menD)
SENE: IA1_11500
SBG: SBG_2097(menD)
SBZ: A464_2423
SFL: SF2343(menD)
SFX: S2477(menD)
SFV: SFV_2335(menD)
SFE: SFxv_2587(menD)
SFN: SFy_3334
SFS: SFyv_3409
SFT: NCTC1_02577(menD)
SSN: SSON_2325(menD)
SBO: SBO_2301(menD)
SBC: SbBS512_E2643(menD)
SDY: SDY_2460(menD)
ENC: ECL_03614(menD)
ECLO: ENC_39410
EEC: EcWSU1_03142(menD)
ECLX: LI66_15265
ECLY: LI62_16765
ECLZ: LI64_14700
ESA: ESA_00949
CSK: ES15_1203(menD)
CTU: CTU_28960(menD)
KPN: KPN_02662(menD)
KPU: KP1_3903(menD)
KPP: A79E_1440
KPT: VK055_4853(menD)
KPE: KPK_1487(menD)
KPR: KPR_2045(menD)
KPX: PMK1_00160(menD)
KPNU: LI86_07765
KPNK: BN49_3879(menD)
KVA: Kvar_1391
KOX: KOX_26280
KOE: A225_4156
EAE: EAE_24340
EAR: CCG28950
CKO: CKO_00526
CRO: ROD_26711(menD)
CAMA: F384_12125
EBT: EBL_c12850(menD)
EBF: D782_1400
YPE: YPO2527(menD)
YPK: y1660(menD)
YPH: YPC_1594
YPA: YPA_2019
YPN: YPN_2122
YPM: YP_2338(menD)
YPG: YpAngola_A1785(menD)
YPZ: YPZ3_2233(menD)
YPD: YPD4_2482
YPX: YPD8_2177(menD)
YPW: CH59_63(menD)
YPJ: CH55_83(menD)
YPV: BZ15_1008(menD)
YPL: CH46_2586(menD)
YPS: YPTB2560(menD)
YPO: BZ17_4078(menD)
YPI: YpsIP31758_1482(menD)
YPY: YPK_1589
YPB: YPTS_2654
YPQ: DJ40_3983(menD)
YPU: BZ21_1856(menD)
YPR: BZ20_3649(menD)
YPC: BZ23_2140(menD)
YPF: BZ19_1922(menD)
YEN: YE1375(menD)
YEY: Y11_02441
YEW: CH47_794(menD)
YET: CH48_283(menD)
YEE: YE5303_11591(menD)
YAL: AT01_1165(menD)
YFR: AW19_1835(menD)
YIN: CH53_357(menD)
YKR: CH54_3951(menD)
YRO: CH64_1177(menD)
YRU: BD65_831(menD)
SPE: Spro_3283
SRL: SOD_c31990(menD)
SPLY: Q5A_017365(menD)
SMAF: D781_3076
SMW: SMWW4_v1c33930(menD)
SMAR: SM39_2881(menD)
SMAC: SMDB11_2680(menD)
SERF: L085_11720
RAA: Q7S_06135
ECA: ECA1211(menD)
PATR: EV46_06090
PATO: GZ59_12400(menD)
PCT: PC1_1111
PEC: W5S_3201
SOD: Sant_1357(menH)
DDD: Dda3937_01781(menD)
DDQ: DDI_0951
EBI: EbC_30520(menD)
PLU: plu3073(menD)
PAY: PAU_01538(menD)
PMR: PMI1745(menD)
PMIB: BB2000_1853(menD)
XBO: XBJ1_0740(menD)
XBV: XBW1_2775(menD)
XNE: XNC1_2845(menD)
XNM: XNC2_2740(menD)
XDO: XDD1_2570(menD)
XPO: XPG1_1253(menD)
PSI: S70_02320
PSX: DR96_3624(menD)
PRG: RB151_026560(menD)
PHEI: NCTC12003_01571(menD)
MMK: MU9_2542
ETR: ETAE_2358(menD)
ETD: ETAF_2130
ETE: ETEE_0381(menD)
LRI: NCTC12151_01275(menD)
PSHI: SAMEA2665130_2007(menD)
HIN: HI0283(menD)
HIT: NTHI0392(menD)
HIU: HIB_04010
HIE: R2846_0297(menD)
HIZ: R2866_0296(menD)
HIK: HifGL_001789(menD)
HIA: H733_0179
HIW: NTHI477_01328(menD)
HIC: NTHIC486_00705(menD)
HIX: NTHI723_01410(menD)
HDU: HD_1853(menD)
HAP: HAPS_1250(menD)
HPAZ: K756_00425
HPAS: JL26_11130
HPAK: JT17_09345
HSO: HS_0617(menD)
HSM: HSM_0968
PMU: PM0054(menD)
PMV: PMCN06_1254(menD)
PMP: Pmu_12680(menD)
PMUL: DR93_2024(menD)
PDAG: 4362423_00350(menD)
MSU: MS1794(menD)
MHT: D648_2930
MHAT: B824_23760
MHX: MHH_c08360(menD)
MHAE: F382_09340
MHAM: J450_08285
MHAO: J451_09560
MHAL: N220_01420
MHAQ: WC39_12415
MHAY: VK67_12420
MVI: X808_1920
MVG: X874_2000
APL: APL_1750(menD)
APJ: APJL_1785(menD)
APA: APP7_1835(menD)
ASU: Asuc_0785
AAT: D11S_2019
AAN: D7S_01920
AACN: AANUM_0040
BTO: WQG_21330
BTRE: F542_1260
BTRH: F543_1300
BTRA: F544_21880
VCH: VC1975
VCS: MS6_1732
VCE: Vch1786_I1467(menD)
VCI: O3Y_09540
VCO: VC0395_A1561(menD)
VCR: VC395_2090(menD)
VCM: VCM66_1899(menD)
VCX: VAA049_904(menD)
VCZ: VAB027_2611(menD)
VVU: VV1_3172(menD)
VVY: VV1116
VVL: VV93_v1c10370(menD)
VPA: VP0929
VPB: VPBB_0887
VAG: N646_0002
VSP: VS_2191
VNI: VIBNI_A2414(menD)
VAN: VAA_03317
VAU: VANGNB10_cI1811c(menD)
VSC: VSVS12_01285(menD)
VTA: A1985(menD)
VFI: VF_1671(menD)
VFM: VFMJ11_1796(menD)
VSA: VSAL_I1099(menD)
AWD: AWOD_I_1790(menD)
PPR: PBPRA2624(C2808)
SON: SO_4573(menD)
SFR: Sfri_0282
SAZ: Sama_3460
SBL: Sbal_0178
SSE: Ssed_0226
SPL: Spea_3971
SHL: Shal_0297
SWD: Swoo_0209
SWP: swp_4792
SVO: SVI_0220(menD)
SPSW: Sps_00299
PIN: Ping_0352
FBL: Fbal_0044
MVS: MVIS_2786(menD)
MYA: MORIYA_1409(menD)
TTU: TERTU_2728(menD)
HHA: Hhal_1127
TNI: TVNIR_1661(menD_[H])
HAM: HALO0680
RFO: REIFOR_00522(menD)
AHA: AHA_0531(menD)
ASA: ASA_3737(menD)
AVR: B565_0486
AMED: B224_4842
ASR: WL1483_834(menD)
TAU: Tola_0433
TBN: TBH_C0632(menD)
RGE: RGE_06720(menD)
DSU: Dsui_2922
DAR: Daro_2345
ACOM: CEW83_08590(menD)
DPS: DP0253
DAL: Dalk_1405
MXA: MXAN_3528(menD)
CCX: COCOR_04515(menD)
SUR: STAUR_4045(menD)
SCL: sce3012(menD)
CCRO: CMC5_043570(menD)
HOH: Hoch_5717
SAT: SYN_02399
BBA: Bd3484(menD)
BBAT: Bdt_3393(menD)
BBW: BDW_12900
BBAC: EP01_02585
BEX: A11Q_484
BMX: BMS_1661(menD)
BVR: BVIR_917
AZL: AZL_b05700(menD)
BSU: BSU30820(menD)
BSR: I33_3141(menD)
BSL: A7A1_2152
BSH: BSU6051_30820(menD)
BSUT: BSUB_03272(menD)
BSUL: BSUA_03272(menD)
BSUS: Q433_16720
BSS: BSUW23_14960(menD)
BST: GYO_3336(menD)
BSO: BSNT_09505(menD)
BSQ: B657_30820(menD)
BSX: C663_2931(menD)
BLI: BL02408(menD)
BLD: BLi03222(menD)
BLH: BaLi_c32960(menD)
BAY: RBAM_027800(menD)
BAQ: BACAU_2792(menD)
BYA: BANAU_2994(menD)
BAMP: B938_14340
BAML: BAM5036_2714(menD)
BAMA: RBAU_2914(menD)
BAMN: BASU_2720(menD)
BAMB: BAPNAU_2947(menD)
BAMT: AJ82_15750
BAMY: V529_30600(menD)
BMP: NG74_02923(menD)
BAO: BAMF_2862(menD)
BAZ: BAMTA208_15085(menD)
BQL: LL3_03158(menD)
BXH: BAXH7_03091(menD)
BQY: MUS_3369(menD)
BAMI: KSO_005170
BAMC: U471_29020
BAMF: U722_15000
BAN: BA_5111(menD)
BAR: GBAA_5111(menD)
BAT: BAS4750
BAH: BAMEG_5145(menD)
BAI: BAA_5123(menD)
BANT: A16_51070
BANR: A16R_51700
BANS: BAPAT_4903
BANV: DJ46_3768(menD)
BCE: BC4855
BCA: BCE_5015(menD)
BCZ: BCE33L4610(menD)
BCR: BCAH187_A4997(menD)
BCB: BCB4264_A4986(menD)
BCU: BCAH820_4968(menD)
BCG: BCG9842_B0252(menD)
BCQ: BCQ_4673(menD)
BCX: BCA_4991(menD)
BAL: BACI_c48610(menD)
BNC: BCN_4773
BCF: bcf_24345
BCER: BCK_10860
BTK: BT9727_4588(menD)
BTL: BALH_4421(menD)
BTB: BMB171_C4494(menD)
BTT: HD73_5172
BTHI: BTK_25505
BTC: CT43_CH4880(menD)
BTM: MC28_4145(menD)
BTG: BTB_c50160(menD)
BTI: BTG_24520
BTW: BF38_611(menD)
BWW: bwei_0026(menD)
BMYO: BG05_1168(menD)
BMYC: DJ92_1940(menD)
BPU: BPUM_2718
BPUM: BW16_14655
BPUS: UP12_13910
BMQ: BMQ_4891(menD)
BMD: BMD_4877(menD)
BMH: BMWSH_0355(menD)
BMEG: BG04_1880(menD)
BAG: Bcoa_2398
BCOA: BF29_1162(menD)
BJS: MY9_3086
BMET: BMMGA3_13700(menD)
BACW: QR42_13730
BACP: SB24_14840
BACB: OY17_17215
BACO: OXB_0012
BACY: QF06_13595
BACL: BS34A_33480(menD)
BALM: BsLM_3068
BEO: BEH_21865
BGY: BGLY_3639(menD)
OIH: OB2325(menD)
GKA: GK2875
GTN: GTNG_2773
GGH: GHH_c29500(menD)
GEA: GARCT_02904(menD)
AFL: Aflv_0381(menD)
ANM: GFC28_3291(menD)
AAMY: GFC30_3234(menD)
ANL: GFC29_2143(menD)
LSP: Bsph_4277(menD)
VPN: A21D_02869(menD)
SAU: SA0896(menD)
SAV: SAV1043(menD)
SAW: SAHV_1036(menD)
SAM: MW0927(menD)
SAS: SAS0979
SAR: SAR1017
SAC: SACOL1052(menD)
SAX: USA300HOU_0991(menD)
SAA: SAUSA300_0946(menD)
SAE: NWMN_0913(memD)
SAD: SAAV_1007(menD)
SUE: SAOV_0989
SUJ: SAA6159_00900(menD)
SUK: SAA6008_00998(menD)
SUC: ECTR2_899(menD)
SUZ: MS7_1001(menD)
SUG: SAPIG1041(menD)
SAUA: SAAG_02154
SAUE: RSAU_000932(menD)
SAUS: SA40_0914
SAUU: SA957_0929
SAUG: SA268_0931
SAUT: SAI1T1_2007370(menD)
SAUJ: SAI2T2_1007390(menD)
SAUK: SAI3T3_1007380(menD)
SAUQ: SAI4T8_1007370(menD)
SAUV: SAI7S6_1007380(menD)
SAUW: SAI5S5_1007340(menD)
SAUX: SAI6T6_1007350(menD)
SAUY: SAI8T7_1007380(menD)
SAUF: X998_1043
SAB: SAB0910
SUY: SA2981_0998(menD)
SAUB: C248_1068(menD)
SAUM: BN843_9500
SAUC: CA347_960(menD)
SAUR: SABB_01009(menD)
SAUI: AZ30_04980
SAUD: CH52_00665
SAMS: NI36_04990
SEP: SE0744
SER: SERP0630(menD)
SEPP: SEB_00720
SEPS: DP17_2077(menD)
SHA: SH1919(menD)
SHH: ShL2_01782(menD)
SSP: SSP1748
SCA: SCA_0652(menD)
SDT: SPSE_1768(menD)
SPAS: STP1_2104
SXO: SXYL_01892(menD)
SHU: SHYC_09135(menD)
SCAP: AYP1020_0367(menD)
SSCH: LH95_08555
SSCZ: RN70_09035
SAGQ: EP23_01290
MCL: MCCL_1507(menD)
MCAK: MCCS_19430(menD)
LMO: lmo1675(menD)
LMN: LM5578_1822(menD)
LMY: LM5923_1774(menD)
LMOC: LMOSLCC5850_1738(menD)
LMOE: BN418_1982
LMOB: BN419_1985
LMOD: LMON_1742(menD)
LMOW: AX10_02470
LMOQ: LM6179_2426(menD)
LMR: LMR479A_1774(menD)
LMOM: IJ09_01600
LMF: LMOf2365_1699(menD)
LMC: Lm4b_01688(menD)
LMOG: BN389_17030(menD)
LMP: MUO_08615
LMOL: LMOL312_1682(menD)
LMOX: AX24_05945
LMH: LMHCC_0891(menD)
LMQ: LMM7_1764(menD)
LML: lmo4a_1732(menD)
LMS: LMLG_1199
LMW: LMOSLCC2755_1687(menD)
LMX: LMOSLCC2372_1740(menD)
LMZ: LMOSLCC2482_1739(menD)
LMON: LMOSLCC2376_1634(menD)
LMOS: LMOSLCC7179_1648(menD)
LMOO: LMOSLCC2378_1696(menD)
LMOY: LMOSLCC2479_1738(menD)
LMOT: LMOSLCC2540_1758(menD)
LMOA: LMOATCC19117_1690(menD)
LMOK: CQ02_08590
LIN: menD
LWE: lwe1693(menD)
LSG: lse_1643(menD)
LIV: LIV_1650(menD)
ESI: Exig_0627
EAN: Eab7_0602(menD)
AAC: Aaci_1918
AAD: TC41_2017(menD)
SIV: SSIL_1096(menD)
JEO: JMA_25510
KUR: ASO14_770(menD)
LLA: L0169(menD)
LLK: LLKF_0751(menD)
LLT: CVCAS_0693(menD)
LLS: lilo_0663(menD)
LLX: NCDO2118_0747(menD)
LLC: LACR_0773
LLM: llmg_1829(menD)
LLR: llh_9210
LLI: uc509_0737(menD)
LLW: kw2_0680(menD) kw2_0910
LLJ: LG36_0713(menD)
LGR: LCGT_0619
LGV: LCGL_0638
LPAP: LBPC_2383
EFA: EF0448(menD)
EFL: EF62_0767(menD)
EFI: OG1RF_10333(menD)
EFS: EFS1_0328(menD)
EFN: DENG_00434(menD)
EFQ: DR75_2438(menD)
ENE: ENT_25410
EHR: EHR_11560
ECAS: ECBG_02739
EMU: EMQU_1438
LME: LEUM_0752
LMM: MI1_03445
LMK: LMES_0676
LCI: LCK_00952(menD)
LKI: LKI_00995
LGS: LEGAS_0913(menD)
WCE: WS08_0960
WCT: WS74_1026
CML: BN424_3101(menD)
CPAS: Clopa_1975
CPAT: CLPA_c25500(menD)
CPAE: CPAST_c25500(menD)
DSY: DSY0518(menD)
DHD: Dhaf_0470
AWO: Awo_c13320(menD)
TMR: Tmar_1623
SAY: TPY_3627(menD)
VPR: Vpar_0374
VRM: 44547418_00395(menD)
LPIL: LIP_2425
MTU: Rv0555(menD)
MTV: RVBD_0555
MTC: MT0581(menD)
MRA: MRA_0562(menD)
MTUR: CFBS_0579(menD)
MTO: MTCTRI2_0563(menD)
MTD: UDA_0555(menD)
MTN: ERDMAN_0608(menD)
MTUE: J114_02970
MTUH: I917_03965
MTUL: TBHG_00552
MTUT: HKBT1_0579(menD)
MTUU: HKBT2_0579(menD)
MTQ: HKBS1_0579(menD)
MBO: BQ2027_MB0570(menD)
MBB: BCG_0600(menD)
MBT: JTY_0570(menD)
MBM: BCGMEX_0571(menD)
MBX: BCGT_0339
MAF: MAF_05620(menD)
MMIC: RN08_0621
MCE: MCAN_05581(menD)
MCQ: BN44_10616(menD)
MCV: BN43_10607(menD)
MCX: BN42_20294(menD)
MCZ: BN45_10622(menD)
MLE: ML2270(menD)
MLB: MLBr02270(menD)
MPA: MAP_4052(menD)
MAO: MAP4_4175
MAVI: RC58_20710
MAVU: RE97_20760
MAV: MAV_4588
MIT: OCO_44720
MIA: OCU_44460
MID: MIP_06792
MYO: OEM_44910
MIR: OCQ_45860
MLP: MLM_3753
MUL: MUL_0654(menD)
MMC: Mmcs_0751
MKM: Mkms_0765
MJL: Mjls_0745
MMI: MMAR_0901(menD)
MMAE: MMARE11_08510(menD)
MMM: W7S_22515
MHAD: B586_19240
MSG: MSMEI_1077(menD)
MVA: Mvan_0975
MGI: Mflv_5263
MPHL: MPHLCCUG_04397(menD)
MVQ: MYVA_0768
MTHN: 4412656_00672(menD)
MAB: MAB_3933c
MABB: MASS_3946
MCHE: BB28_20255
MSTE: MSTE_04105(menD)
MJD: JDM601_0549(menD)
MTER: 4434518_00549(menD)
ASD: AS9A_0385(menD)
CGL: NCgl0450(Cgl0467)
CGB: cg0552(menD)
CGU: WA5_0450(MenD)
CGT: cgR_0570
CGM: cgp_0552(menD)
CGJ: AR0_02885
CEF: CE0478
CDI: DIP0423
CDP: CD241_0361(menD)
CDH: CDB402_0337(menD)
CDT: CDHC01_0363(menD)
CDE: CDHC02_0373(menD)
CDR: CDHC03_0352(menD)
CDA: CDHC04_0333(menD)
CDZ: CD31A_0424(menD)
CDB: CDBH8_0362(menD)
CDS: CDC7B_0368(menD)
CDD: CDCE8392_0375(menD)
CDV: CDVA01_0316(menD)
CDIP: ERS451417_00345(menD)
CJK: jk1868(menD)
CUR: cu0260
CUA: CU7111_0264(menD)
CAR: cauri_0345(menD)
CPU: cpfrc_00296(menD)
CPL: Cp3995_0300(menD)
CPG: Cp316_0307(menD)
CPP: CpP54B96_0302(menD)
CPK: Cp1002_0299(menD)
CPQ: CpC231_0303(menD)
CPX: CpI19_0301(menD)
CPZ: CpPAT10_0304(menD)
COR: Cp267_0312(menD)
COP: Cp31_0305(menD)
COD: Cp106_0291(menD)
COS: Cp4202_0296(menD)
COI: CpCIP5297_0305(menD)
COE: Cp258_0301(menD)
COU: Cp162_0296(menD)
CPSE: CPTA_00829
CPSU: CPTB_00703
CPSF: CPTC_00365
CRD: CRES_1921(menD)
CUL: CULC22_00347(menD)
CUC: CULC809_00343(menD)
CUE: CULC0102_0389(menD)
CUN: Cul210932_0357(menD)
CUS: CulFRC11_0340(menD)
CUQ: Cul210931_0345(menD)
CUZ: Cul05146_0369(menD)
CUJ: CUL131002_0342(menD)
CVA: CVAR_2422(menD)
CTER: A606_09995
CGY: CGLY_03360(menD)
COA: DR71_1396(menD)
CSX: CSING_01930(menD)
CMQ: B840_01685(menD)
CKU: UL82_01355(menD)
CCJ: UL81_01545(menD)
CMV: CMUST_01815(menD)
CEI: CEPID_01765(menD)
CTED: CTEST_01795(menD)
CUT: CUTER_01405(menD)
CDX: CDES_02495(menD)
CSP: WM42_1014(menD)
CPHO: CPHO_01800
CGV: CGLAU_01565(menD)
CAQU: CAQU_01535
CAMG: CAMM_02230
CMIN: NCTC10288_02187(menD)
NFA: NFA_51330(menD)
NFR: ERS450000_04754(menD)
NNO: NONO_c69770(menD)
RHA: RHA1_ro01997(menD)
RER: RER_17040(menD)
REY: O5Y_08140
ROP: ROP_16710(menD)
REQ: REQ_36990(menD)
RHB: NY08_4813
RFA: A3L23_02881(menD)
RHS: A3Q41_00480(menD)
RHU: A3Q40_00307(menD)
RRT: 4535765_03648(menD)
GBR: Gbro_1092
GPO: GPOL_c11640(menD)
GOR: KTR9_0959
TPR: Tpau_0729
SRT: Srot_0606
SMAL: SMALA_7641
TWH: TWT_068(menD)
TWS: TW078(menD)
LXX: Lxx01490(menD)
CMI: CMM_2812(menD)
CMS: CMS3017(menD)
CMC: CMN_02772(menD)
MTS: MTES_2349
MHOS: CXR34_03975(menD)
AGM: DCE93_01585(menD)
CRY: B7495_01210(menD)
AUW: AURUGA1_01525(menD)
MALK: MalAC0309_2596(menD)
MYL: C3E77_01740(menD)
SALC: C2138_00935(menD)
HUM: DVJ78_17395(menD)
ART: Arth_3138
ARR: ARUE_c32600(menD)
ARM: ART_2298
ARN: CGK93_17660(menD)
ARX: ARZXY2_577(menD)
ARTH: C3B78_14945(menD)
AAU: AAur_3107(menD)
ACH: Achl_2834
AAI: AARI_24200(menD)
KRH: KRH_05390(menD)
RDN: HMPREF0733_10414(menD)
AUL: DCC27_012060(menD)
BCV: Bcav_3235
BGG: CFK41_04400(menD)
BRZ: CFK38_06695(menD)
BSAU: DWV08_09570(menD)
JDE: Jden_0534
LMOI: VV02_22175
XCE: Xcel_0458
IDO: I598_1727(menD)
CFL: Cfla_2722
CFI: Celf_0928
SERJ: SGUI_2774
ORN: DV701_16300(menD)
BLIN: BLSMQ_1072
DCO: SAMEA4475696_2136(menD)
PAC: PPA0903
PAK: HMPREF0675_3960(menD)
PAW: PAZ_c09380(menD)
PACC: PAC1_04765
PACH: PAGK_1248
CACN: RN83_04880
CGRN: 4412665_01023(menD)
PFR: PFREUD_07490(menD)
PFRE: RM25_0716
PPC: HMPREF9154_2422(menD)
PBO: PACID_13890(menD)
ACIJ: JS278_01942(menD)
MPH: MLP_07720(menD)
NCA: Noca_0510
NDK: I601_0794(menD)
KFL: Kfla_6310
PSIM: KR76_03770
MGG: MPLG2_0331(menD)
TFU: Tfu_1411
NDA: Ndas_2565
NAL: B005_5232(menD)
TCU: Tcur_2402
SRO: Sros_4019
NML: Namu_0965
GOB: Gobs_4562
BSD: BLASA_4458(menD)
MMAR: MODMU_4977(menD)
KRA: Krad_0646
SEN: SACE_6913(menD)
AMD: AMED_0510(menD)
AMN: RAM_02615
AMM: AMES_0508(menD)
AMZ: B737_0509(menD)
AOI: AORI_0509(menD)
AJA: AJAP_37095(menD)
AMQ: AMETH_0472(menD)
PDX: Psed_5587
PSEE: FRP1_01230
PSEH: XF36_00610
AMI: Amir_6702
SESP: BN6_80510(menD)
KAL: KALB_8312
ACTI: UA75_02500
ACAD: UA74_02495
AHG: AHOG_02440(menD)
ACTA: C1701_12935(menD)
AHE: Arch_0288
TPYO: X956_08360
BLO: BL0231
BLF: BLIF_0378
BLG: BIL_14900
BDE: BDP_1868(menD)
BDN: BBDE_1768
BBRE: B12L_0377
BBRD: BBBR_0380
BSCA: BBSC_2111
TBI: Tbis_1708
ABAM: B1s21122_00590(menD)
RXY: Rxyl_2896
CWO: Cwoe_3575
AFO: Afer_1625
AYM: YM304_24010(menD)
ELE: Elen_2976
AEQ: AEQU_2028
SYN: sll0603(menD)
SYZ: MYO_124280(menD)
SYY: SYNGTS_2403(menD)
SYT: SYNGTI_2402(menD)
SYS: SYNPCCN_2401(menD)
SYQ: SYNPCCP_2401(menD)
SYJ: D082_06200(menD)
SYW: SYNW0997(menD)
SYC: syc0121_d(menD)
SYG: sync_1526(menD)
SYR: SynRCC307_1140(menD)
SYX: SynWH7803_1021(menD)
SYP: SYNPCC7002_A1531(menD)
CYA: CYA_0082(menD)
CYB: CYB_2045(menD)
SYNR: KR49_03320
SYND: KR52_11020
SYH: Syncc8109_1566(menD)
SYNW: SynWH8103_01128(menD)
TEL: tll0130(menD)
CYI: CBM981_0730(menD)
LET: O77CONTIG1_04847(menD)
HHG: XM38_030670(menD)
PMA: Pro_1054(menD)
PMM: PMM0607(menD)
PMT: PMT_0406
PMB: A9601_06631(menD)
PMC: P9515_06721(menD)
PMF: P9303_18801(menD)
PMG: P9301_06331(menD)
PMH: P9215_06891(menD)
PMJ: P9211_10431(menD)
PME: NATL1_06631(menD)
PRC: EW14_0652
PRM: EW15_0705
AMR: AM1_1108(menD)
MAR: MAE_26640(menD)
MPK: VL20_4258
CYL: AA637_09220(menD)
CYT: cce_1865(menD)
TER: Tery_4077
ARP: NIES39_C02430(menD)
ANA: alr0312(menD)
NON: NOS3756_46060(menD)
AVA: Ava_4706
NAZ: Aazo_0920
ANB: ANA_C13337(menD)
CALH: IJ00_23365
NSP: BMF81_03237(menD)
CTHE: Chro_3067
RCA: Rcas_4217
CAU: Caur_3655
CAG: Cagg_0220
TRO: trd_A0261(menD)
STI: Sthe_3024
CAP: CLDAP_22850(menD)
PBF: CFX0092_A0432(menD)
TTR: Tter_1233
PCU: pc1068(menD)
PNL: PNK_0812(menD)
PUV: PUV_20300(menD)
WCH: wcw_1017(menD1) wcw_1025(menD3)
SNG: SNE_A14210(menD)
OTE: Oter_3647
OBG: Verru16b_02462(menD)
CAA: Caka_0852
AMU: Amuc_2104
AGL: PYTT_1926
BTH: BT_4701
BTHO: Btheta7330_03286(menD)
BFR: BF1316
BFS: BF9343_1237(menD)
BFG: BF638R_1316(menD)
BVU: BVU_2418
BOA: Bovatus_04934(menD)
BCEL: BcellWH2_01436(menD)
BZG: C4H11_02890(menD)
BHF: C3V43_02840(menD) C3V43_12210(menD)
PGI: PG_1524(menD)
PGT: PGTDC60_0779(menD)
PCRE: NCTC12858_01269(menD)
PBT: ING2E5B_1932(menD)
PMUC: ING2E5A_0607(menD)
PDI: BDI_1136
TFO: BFO_1952(menD_1) BFO_3200(menD_2)
PSAC: PSM36_2534(menD)
PRU: PRU_1685(menD)
PMZ: HMPREF0659_A6049(menD)
PDN: HMPREF9137_1703(menD)
PIT: PIN17_A1105(menD)
PJE: CRM71_05895(menD)
ASX: CDL62_12100(menD)
MBAS: ALGA_3206
SRU: SRU_1351(menD)
SRM: SRM_01545(menD)
RMR: Rmar_0582
CHU: CHU_1759(menD)
DFE: Dfer_1055
SLI: Slin_1992
SPIR: CWM47_14630(menD)
RUN: DR864_24605(menD)
FAE: FAES_3123
PSEZ: HME7025_01601(menD)
ALS: DJ013_01235(menD)
HSW: Hsw_2927
HNV: DDQ68_08845(menD)
FLM: MY04_0592
GFO: GFO_2075(menD)
GFL: GRFL_0140
FJO: Fjoh_2781
FJG: BB050_03694(menD)
FPS: FP1676(menD)
FBR: FBFL15_1028(menD)
FIN: KQS_10050(menD)
FAT: DVK85_10765(menD)
COC: Coch_2037
CGH: CGC50_00450(menD)
ZPR: ZPR_1715
RAI: RA0C_1353
RAR: RIA_1135
RAG: B739_0800
RAE: G148_0525
RAT: M949_1263
MARM: YQ22_15175
MARB: CJ263_00425(menD)
CBAL: M667_13820
CBAT: M666_13690
DOK: MED134_13991(menD)
DDO: I597_1592(menD)
DOD: DCS32_00965(menD)
LACI: CW733_03555(menD)
ZGA: ZOBELLIA_4021(menD)
MLT: VC82_2616
NDO: DDD_3388(menD)
NOB: CW736_09470(menD)
POM: MED152_04020(menD)
EAO: BD94_0036
ELB: VO54_02570(menD)
MYR: MYRA21_3539(menD)
MPW: MPR_2358
CHZ: CHSO_0669(menD)
CIO: CEQ15_17530(menD)
CHRY: CEY12_13805(menD)
CPIP: CJF12_14930(menD)
CTAK: 4412677_01633(menD)
WIN: WPG_3376
TJE: TJEJU_3316(menD)
TMAR: MARIT_2320(menD)
AALG: AREALGSMS7_04205(menD)
AUE: C5O00_11545(menD)
SPON: HME9304_02952(menD)
KOS: KORDIASMS9_04152(menD)
MARF: CJ739_3631
FBA: FIC_02456
FBU: UJ101_02476(menD)
BBL: BLBBGE_056(menD)
BPI: BPLAN_577(menD)
BMM: MADAR_549(menD)
BCP: BLBCPU_055(menD)
BBG: BGIGA_570(menD)
BLP: BPAA_576(menD)
BLU: K645_291
FLU: CHH17_12025(menD)
CTE: CT1839(menD)
CPC: Cpar_0364
CCH: Cag_1700
CLI: Clim_2048
PVI: Cvib_0397
PLT: Plut_0331
PPH: Ppha_2423
PAA: Paes_1878
PROC: Ptc2401_01966(menD)
PROS: CHL67_09995(menD)
CTS: Ctha_1989
IAL: IALB_1320(menD)
MRO: MROS_1450
HAL: VNG_1081G(menD)
HSL: OE_2563R(menD)
HHB: Hhub_2286(menD)
HALH: HTSR_1291(menD)
HHSR: HSR6_1364(menD)
HSU: HLASF_1308(menD)
HSF: HLASA_1295(menD)
HMA: rrnAC0838(menD)
HHI: HAH_1477(menD)
NPH: NP_2726A(menD)
NMO: Nmlp_2003(menD)
HUT: Huta_0815
HTI: HTIA_0691(menD)
HMU: Hmuk_2535
HWA: HQ_1873A(menD)
HWC: Hqrw_2011(menD)
HVO: HVO_1469(menD)
HME: HFX_1532(menD)
HLA: Hlac_1290
HTU: Htur_1783
NMG: Nmag_3569(menD)
NAT: NJ7G_3033
SALI: L593_14910
 » show all
Taxonomy
Reference
1  [PMID:17760421]
  Authors
Jiang M, Cao Y, Guo ZF, Chen M, Chen X, Guo Z.
  Title
Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity.
  Journal
Biochemistry 46:10979-89 (2007)
DOI:10.1021/bi700810x
  Sequence
[eco:b2264]
Other DBs
ExplorEnz - The Enzyme Database: 2.2.1.9
IUBMB Enzyme Nomenclature: 2.2.1.9
ExPASy - ENZYME nomenclature database: 2.2.1.9
BRENDA, the Enzyme Database: 2.2.1.9
CAS: 1112282-73-1

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