KEGG   ENZYME: 2.3.1.101Help
Entry
EC 2.3.1.101                Enzyme                                 

Name
formylmethanofuran---tetrahydromethanopterin N-formyltransferase;
formylmethanofuran-tetrahydromethanopterin formyltransferase;
formylmethanofuran:tetrahydromethanopterin formyltransferase;
N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase;
FTR;
formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase
Reaction(IUBMB)
formylmethanofuran + 5,6,7,8-tetrahydromethanopterin = methanofuran + 5-formyl-5,6,7,8-tetrahydromethanopterin [RN:R03390]
Reaction(KEGG)
Substrate
formylmethanofuran [CPD:C01001];
5,6,7,8-tetrahydromethanopterin [CPD:C01217]
Product
methanofuran [CPD:C00862];
5-formyl-5,6,7,8-tetrahydromethanopterin [CPD:C01274]
Comment
Methanofuran is a complex 4-substituted furfurylamine and is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum.
History
EC 2.3.1.101 created 1989
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00672  formylmethanofuran--tetrahydromethanopterin N-formyltransferase
Genes
MCA: MCA2858
MMT: Metme_0668
MDN: JT25_013495
MDH: AYM39_03060
MKO: MKLM6_0653
MAH: MEALZ_1269(ffsA)
MPSY: CEK71_00135(fhcD)
MEJ: Q7A_285(fhcD)
MEC: Q7C_1963
TIG: THII_0586
NOC: Noc_0023
NHL: Nhal_0013
NWA: Nwat_0021
NTT: TAO_0008
BUE: BRPE67_BCDS01180(ffsA)
BXE: Bxe_B2463(fhcD)
BXB: DR64_4790(fhcD)
PARB: CJU94_31065(fhcD)
PHS: C2L64_21750(fhcD) C2L64_38180(fhcD)
PTER: C2L65_26245(fhcD) C2L65_34175(fhcD)
PGP: CUJ91_21370(fhcD)
MPT: Mpe_A2625
LCH: Lcho_3134
RGE: RGE_40410(fhcD)
AON: DEH84_18925(fhcD)
METR: BSY238_3298(fhcD)
MFA: Mfla_1664
MMB: Mmol_0859
MEH: M301_0910
MEP: MPQ_1571(ftr)
MBAC: BN1209_0741(ffsA)
AZA: AZKH_p0240(fhcD)
THK: CCZ27_13180(fhcD)
RGA: RGR602_PC01561(ffsA)
XAU: Xaut_1794
SNO: Snov_0757
MEX: Mext_1825
MEA: Mex_1p1756(fhcD)
MDI: METDI2508(fhcD)
MCH: Mchl_2160
MPO: Mpop_1776
MET: M446_5774
MNO: Mnod_5998
MOR: MOC_0679(fhcD)
META: Y590_08740
MAQU: Maq22A_c16440(fhcD)
MEE: DA075_05675(fhcD)
METD: C0214_10495(fhcD)
MSL: Msil_2402
HDN: Hden_1609
HMC: HYPMC_1887(ffsA)
FIL: BN1229_v1_0555(fhcD)
FIY: BN1229_v1_0557(fhcD)
MSC: BN69_0584
MTW: CQW49_03835(fhcD)
MCG: GL4_1794
HDI: HDIA_2304(fhcD)
ALI: AZOLI_p10692(ffsA1) AZOLI_p10895(ffsA2)
ABS: AZOBR_p270089(ffsA)
AZT: TSH58p_01170(fhcD)
AZM: DM194_17105(fhcD)
RBA: RB9835(ffsA)
PSL: Psta_0715
PIR: VN12_16340(fhcD_1) VN12_25910(fhcD_2)
PLM: Plim_0767
PLS: VT03_25050(fhcD_1) VT03_26560(fhcD_2)
PLH: VT85_05450(fhcD)
FMR: Fuma_04732(fhcD)
GES: VT84_05645(fhcD_1) VT84_15260(fhcD_2)
GOG: C1280_03970(fhcD) C1280_18540(fhcD)
IPA: Isop_0523
SACI: Sinac_1239
PBOR: BSF38_00166(fhcD)
MOX: DAMO_0459(fhcD)
MJA: MJ_0318
MMP: MMP1609(ftr)
MMD: GYY_08900
MAE: Maeo_0224
MVO: Mvol_1497
MMG: MTBMA_c08020(ehaS) MTBMA_c16460(ftr)
MWO: MWSIV6_0792(ehaS) MWSIV6_1651(ftr)
METE: tca_00370(fhcD_1) tca_01215(fhcD_2)
MST: Msp_0070(ftr2) Msp_1502(ftr1)
MRU: mru_1393(ftr1) mru_2022(ftr2)
MEB: Abm4_0936(ftr1) Abm4_1598(ftr2)
MMIL: sm9_0727(ftr1) sm9_2108(ftr2)
METH: MBMB1_1128(ehaS) MBMB1_1832(ftr)
MFC: BRM9_1337(ftr) BRM9_2162(ftr2)
MFI: DSM1535_1101(ftr) DSM1535_2022(ehaS)
MCUB: MCBB_1014(ehaS) MCBB_2124(ftr)
MKA: MK0116(ftr_1) MK0816(ftr_2)
MAC: MA_0010(ftr)
MBAR: MSBR2_3465
MBAK: MSBR3_3472
MMA: MM_1321
MMAC: MSMAC_3365
METM: MSMTP_3245
MTHE: MSTHC_1461
MTHR: MSTHT_1825
MHOR: MSHOH_4088
MBU: Mbur_1728(ftr)
MMET: MCMEM_2199
MMH: Mmah_2027
MPY: Mpsy_1734
MTP: Mthe_1643
MCJ: MCON_1472(fhcD)
MHI: Mhar_2214
MHU: Mhun_1808
MLA: Mlab_0215
MBG: BN140_1723(ftr)
MEMA: MMAB1_2217(ftr)
MPI: Mpet_2482
MBN: Mboo_0593
MPL: Mpal_2244
MPD: MCP_1033(ftr)
MEZ: Mtc_1916(ftr)
RCI: LRC202(ftr)
BARC: AOA65_1220(ftr_1) AOA65_2064(ftr_2)
BARB: AOA66_0598(ftr)
LOKI: Lokiarch_11730(ftr_1) Lokiarch_20800(ftr_2)
 » show all
Taxonomy
Reference
1  [PMID:3097011]
  Authors
Donnelly MI, Wolfe RS.
  Title
The role of formylmethanofuran: tetrahydromethanopterin formyltransferase in methanogenesis from carbon dioxide.
  Journal
J Biol Chem 261:16653-9 (1986)
Reference
2
  Authors
Leigh, J.A., Rinehart, K.L. and Wolfe, R.S.
  Title
Structure of methanofuran, the carbon-dioxide reduction factor of Methanobacterium thermoautotrophicum.
  Journal
J Am Chem Soc 106:3636-3640 (1984)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.101
IUBMB Enzyme Nomenclature: 2.3.1.101
ExPASy - ENZYME nomenclature database: 2.3.1.101
UM-BBD (Biocatalysis/Biodegradation Database): 2.3.1.101
BRENDA, the Enzyme Database: 2.3.1.101
CAS: 105669-83-8

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