KEGG   ENZYME: 2.3.1.122Help
Entry
EC 2.3.1.122                Enzyme                                 

Name
trehalose O-mycolyltransferase;
alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase;
alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
alpha,alpha-trehalose-6-mycolate:alpha,alpha-trehalose-6-mycolate 6'-mycolyltransferase
Reaction(IUBMB)
2 alpha,alpha-trehalose 6-mycolate = alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate [RN:R07248]
Reaction(KEGG)
Substrate
alpha,alpha'-trehalose 6-mycolate [CPD:C04218]
Product
alpha,alpha-trehalose [CPD:C01083];
alpha,alpha'-trehalose 6,6'-bismycolate [CPD:C04465]
Comment
Catalyses the exchange of mycolic acid between trehalose, trehalose mycolate and trehalose bismycolate. Trehalose 6-palmitate can also act as donor.
History
EC 2.3.1.122 created 1990
Pathway
ec00572  Arabinogalactan biosynthesis - Mycobacterium
Orthology
K18851  diacylglycerol O-acyltransferase / trehalose O-mycolyltransferase
Genes
MTU: Rv0129c(fbpC) Rv1886c(fbpB) Rv3804c(fbpA)
MTV: RVBD_0129c RVBD_1886c RVBD_3804c
MTC: MT0137(fbpC) MT0973 MT1934(fbpB) MT3911(fbpA)
MRA: MRA_0136(fbpC) MRA_1897(fbpB) MRA_3844(fbpA)
MTF: TBFG_10130 TBFG_10964 TBFG_11914 TBFG_13838
MTB: TBMG_00130 TBMG_02108 TBMG_03042 TBMG_03851
MTK: TBSG_00131 TBSG_02119 TBSG_03063 TBSG_03874
MTZ: TBXG_000130 TBXG_002090 TBXG_003023 TBXG_003821
MTG: MRGA327_00840 MRGA327_05945 MRGA327_23425
MTI: MRGA423_00845 MRGA423_05930 MRGA423_11765 MRGA423_24000
MTUR: CFBS_0139(fbpC) CFBS_1978(fbpB) CFBS_4033(fbpA)
MTO: MTCTRI2_0132(fbpC) MTCTRI2_1918(fbpB) MTCTRI2_3883(fbpA)
MTD: UDA_0129c(fbpC) UDA_1886c(fbpB) UDA_3804c(fbpA)
MTN: ERDMAN_0150(fbpC) ERDMAN_2078(fbpB) ERDMAN_4170(fbpA)
MTUT: HKBT1_0139(fbpC) HKBT1_1975(fbpB) HKBT1_4016(fbpA)
MTUU: HKBT2_0139(fbpC) HKBT2_1983(fbpB) HKBT2_4026(fbpA)
MTQ: HKBS1_0139(fbpC) HKBS1_1979(fbpB) HKBS1_4029(fbpA)
MBB: BCG_0163c(fbpC) BCG_1923c(fbpB) BCG_3866c(fbpA)
MBT: JTY_0133(fbpC) JTY_1907(fbpB) JTY_3868(fbpA)
MBM: BCGMEX_0133c(fbpC) BCGMEX_1904c(fbpB) BCGMEX_3867c(fbpA)
MAF: MAF_01290(fbpC) MAF_19080(fbpB) MAF_38190(fbpA)
MCE: MCAN_01321(fbpC) MCAN_19011(fbpB) MCAN_38231(fbpA)
MCV: BN43_10150(fbpC) BN43_20422 BN43_31028(fbpB) BN43_90319(fbpA)
MCX: BN42_10168(fbpC) BN42_30153(fbpB) BN42_90327(fbpA)
MLE: ML0097(fbpA) ML2028(fbpB) ML2655(fbpC2)
MLB: MLBr00097(fbpA) MLBr02028(fbpB) MLBr02655(fbpC2)
MPA: MAP_0216(fbpA) MAP_1609c(fbpB) MAP_3531c(fbpC2)
MUL: MUL_2970(fbpB) MUL_4793(fbpC) MUL_4987(fbpA)
MMI: MMAR_0328(fbpC) MMAR_2777(fbpB) MMAR_4556(fbpC_2) MMAR_5368(fbpA)
MMAE: MMARE11_02980(fbpC) MMARE11_26980(fbpB) MMARE11_43690(fbpC_2) MMARE11_51890(fbpA)
MLI: MULP_00305(fbpC) MULP_02535(fbpB) MULP_04773(fbpC_2) MULP_05647(fbpA)
MPHL: MPHLCCUG_00201(fbpC_1) MPHLCCUG_00202(fbpB_1) MPHLCCUG_01766(fbpB_2) MPHLCCUG_02396(fbpC_3) MPHLCCUG_04293(fbpB_3)
MTHN: 4412656_01363(fbpB) 4412656_02288(fbpC_2) 4412656_02315(fbpC_3) 4412656_03604(fbpC_4) 4412656_04405(fbpC_5) 4412656_04406(fbpA_2)
MJD: JDM601_1973(fbpB) JDM601_3084(fbpB) JDM601_4122(fbpA) JDM601_4182(fbpC)
MTER: 4434518_01923(fbpB_1) 4434518_03072(fbpB_2) 4434518_04061(fbpA) 4434518_04119(fbpC)
ASD: AS9A_0103
CRD: CRES_0530(cmtB)
CTER: A606_00990
CSX: CSING_12345(cmtB)
CPHO: CPHO_11460
CAMG: CAMM_11865
CMIN: NCTC10288_00193(cmtB)
NFA: NFA_1810(fbpA) NFA_1820(fbpB) NFA_1830(fbpC)
NFR: ERS450000_04056(fbpC_2) ERS450000_04057(fbpC_3) ERS450000_04058(fbpC_4)
NCY: NOCYR_0137 NOCYR_0138(fbpB) NOCYR_0139(fbpC) NOCYR_2261(fbpB) NOCYR_4128(fbpC2)
RFA: A3L23_02025(fbpB_1) A3L23_02026(fbpB_2)
RHS: A3Q41_01337(fbpB_3) A3Q41_01338(fbpB_4)
RHU: A3Q40_03644(fbpB)
RRT: 4535765_00216(fbpC_1) 4535765_00853(fbpC_2)
SRT: Srot_2698
 » show all
Taxonomy
Reference
1  [PMID:3654621]
  Authors
Sathyamoorthy N, Takayama K.
  Title
Purification and characterization of a novel mycolic acid exchange enzyme from Mycobacterium smegmatis.
  Journal
J Biol Chem 262:13417-23 (1987)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.122
IUBMB Enzyme Nomenclature: 2.3.1.122
ExPASy - ENZYME nomenclature database: 2.3.1.122
BRENDA, the Enzyme Database: 2.3.1.122
CAS: 111694-11-2

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