KEGG   ENZYME: 2.3.1.198Help
Entry
EC 2.3.1.198                Enzyme                                 

Name
glycerol-3-phosphate 2-O-acyltransferase;
sn-2-glycerol-3-phosphate O-acyltransferase;
glycerol-3-phosphate O-acyltransferase (ambiguous)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:sn-glycerol 3-phosphate 2-O-acyltransferase
Reaction(IUBMB)
an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate [RN:R06872]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
sn-glycerol 3-phosphate [CPD:C00093]
Product
CoA [CPD:C00010];
2-acyl-sn-glycerol 3-phosphate [CPD:C03974]
Comment
A membrane-associated enzyme required for suberin or cutin synthesis in plants. Active with a wide range of acyl-CoA substrates (C16:0-C24:0). The enzyme from some sources has much higher activity with omega-oxidized acyl-CoAs. Some enzymes are bifunctional and have an additional phosphatase activity producing sn-2-monoacylglycerols.
History
EC 2.3.1.198 created 2012
Pathway
ec00564  Glycerophospholipid metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K13508  glycerol-3-phosphate acyltransferase
Genes
ATH: AT1G01610(GPAT4) AT1G02390(GPAT2) AT1G06520(GPAT1) AT2G38110(GPAT6) AT3G11430(GPAT5) AT4G00400(GPAT8) AT4G01950(GPAT3) AT5G06090(GPAT7)
ALY: ARALYDRAFT_349873(ATGPAT7) ARALYDRAFT_470198(ATGPAT2) ARALYDRAFT_478480(ATGPAT5) ARALYDRAFT_482818(ATGPAT6) ARALYDRAFT_490527 ARALYDRAFT_887285(ATGPAT4) ARALYDRAFT_887856 ARALYDRAFT_912037(ATGPAT3)
CRB: 17881073 17881583 17882670 17888745 17892656 17893886 17897851 17898994 17899022
CSAT: 104705302 104707911 104708504 104709920 104711910 104713526 104734612 104737590 104737735 104738637 104738720 104745336 104745343 104754209 104754311 104754807 104758817 104759725 104764417 104764883 104764893 104768801 104772078 104772833 104782244 104785665 104792606
EUS: EUTSA_v10007168mg EUTSA_v10007347mg EUTSA_v10007431mg EUTSA_v10015521mg EUTSA_v10016551mg EUTSA_v10020574mg EUTSA_v10028577mg EUTSA_v10028601mg
BRP: 103836791 103836923 103843800 103844032 103844589 103844663 103845974 103846420 103846954 103858788 103865652 103867137 103870290 103870350
BNA: 106345512 106354755 106358370 106360384 106370865 106370914 106377375 106388796 106388797 106400894 106402301 106405546 106405634 106415493 106419242 106422882 106426094 106426630 106427079 106429323 106429324 106432203 106434164 106434165 106434955 106435594 106435728 106435729 106438654 106447658 106453443 111201229 111206209 111206381
BOE: 106293100 106294683 106294924 106295238 106311526 106313268 106316725 106317070 106317133 106329497 106337253 106342992 106344119
THJ: 104800824 104801308 104801309 104801404 104806599 104815918 104823129 104823385 104826234 104826829
CPAP: 110807735 110814995 110815211 110815224 110819339 110819467 110820900
LJA: Lj0g3v0047509.1(Lj0g3v0047509.1) Lj0g3v0189079.1(Lj0g3v0189079.1) Lj0g3v0263249.1(Lj0g3v0263249.1) Lj0g3v0263249.2(Lj0g3v0263249.2) Lj1g3v2301880.1(Lj1g3v2301880.1) Lj1g3v4834040.1(Lj1g3v4834040.1) Lj1g3v4835150.1(Lj1g3v4835150.1) Lj2g3v0345020.1(Lj2g3v0345020.1) Lj2g3v2612020.1(Lj2g3v2612020.1) Lj2g3v3106320.1(Lj2g3v3106320.1) Lj3g3v2340960.1(Lj3g3v2340960.1) Lj5g3v1585220.1(Lj5g3v1585220.1) Lj6g3v0920870.1(Lj6g3v0920870.1) Lj6g3v0920880.1(Lj6g3v0920880.1) Lj6g3v0920880.2(Lj6g3v0920880.2)
DOSA: Os01t0299300-00(Os01g0299300) Os01t0329000-01(Os01g0329000) Os01t0631400-01(Os01g0631400) Os01t0855000-01(Os01g0855000) Os03t0832800-01(Os03g0832800) Os05t0280500-01(Os05g0280500) Os05t0448300-01(Os05g0448300) Os05t0457800-01(Os05g0457800) Os11t0679700-01(Os11g0679700) Os12t0563000-00(Os12g0563000)
ATS: 109740321(LOC109740321) 109743316(LOC109743316) 109744567(LOC109744567) 109745940(LOC109745940) 109751148(LOC109751148) 109756848(LOC109756848) 109760226(LOC109760226) 109762257(LOC109762257) 109766754(LOC109766754) 109770082(LOC109770082) 109770085(LOC109770085) 109771224(LOC109771224) 109771542(LOC109771542) 109778965(LOC109778965) 109783055(LOC109783055)
 » show all
Taxonomy
Reference
1  [PMID:20551224]
  Authors
Yang W, Pollard M, Li-Beisson Y, Beisson F, Feig M, Ohlrogge J
  Title
A distinct type of glycerol-3-phosphate acyltransferase with sn-2 preference and  phosphatase activity producing 2-monoacylglycerol.
  Journal
Proc Natl Acad Sci U S A 107:12040-5 (2010)
DOI:10.1073/pnas.0914149107
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.198
IUBMB Enzyme Nomenclature: 2.3.1.198
ExPASy - ENZYME nomenclature database: 2.3.1.198
BRENDA, the Enzyme Database: 2.3.1.198

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