KEGG   ENZYME: 2.3.1.199Help
Entry
EC 2.3.1.199                Enzyme                                 

Name
very-long-chain 3-oxoacyl-CoA synthase;
very-long-chain 3-ketoacyl-CoA synthase;
very-long-chain beta-ketoacyl-CoA synthase;
condensing enzyme (ambiguous);
CUT1 (gene name);
CER6 (gene name);
FAE1 (gene name);
KCS (gene name);
ELO (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
malonyl-CoA:very-long-chain acyl-CoA malonyltransferase (decarboxylating and thioester-hydrolysing)
Reaction(IUBMB)
a very-long-chain acyl-CoA + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA [RN:R10825]
Reaction(KEGG)
Substrate
very-long-chain acyl-CoA [CPD:C20876];
malonyl-CoA [CPD:C00083]
Product
very-long-chain 3-oxoacyl-CoA [CPD:C20877];
CO2 [CPD:C00011];
CoA [CPD:C00010]
Comment
This is the first component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. Multiple forms exist with differing preferences for the substrate, and thus the specific form expressed determines the local composition of very-long-chain fatty acids [6,7]. For example, the FAE1 form from the plant Arabidopsis thaliana accepts only 16 and 18 carbon substrates, with oleoyl-CoA (18:1) being the preferred substrate [5], while CER6 from the same plant prefers substrates with chain length of C22 to C32 [4,8]. cf. EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase
History
EC 2.3.1.199 created 2012
Pathway
ec00062  Fatty acid elongation
ec01040  Biosynthesis of unsaturated fatty acids
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K10203  elongation of very long chain fatty acids protein 6
K10205  elongation of very long chain fatty acids protein 2
K10244  elongation of very long chain fatty acids protein 5
K10245  fatty acid elongase 2
K10246  fatty acid elongase 3
K10247  elongation of very long chain fatty acids protein 1
K10248  elongation of very long chain fatty acids protein 3
K10249  elongation of very long chain fatty acids protein 4
K10250  elongation of very long chain fatty acids protein 7
K15397  3-ketoacyl-CoA synthase
Genes
HSA: 54898(ELOVL2) 60481(ELOVL5) 64834(ELOVL1) 6785(ELOVL4) 79071(ELOVL6) 79993(ELOVL7) 83401(ELOVL3)
PTR: 456820(ELOVL1) 461436(ELOVL6) 462842(ELOVL4) 472038(ELOVL5) 736134(ELOVL7) 745450(ELOVL3) 750765(ELOVL2)
PPS: 100968249(ELOVL4) 100973834(ELOVL7) 100976431(ELOVL6) 100979903(ELOVL2) 100984036(ELOVL3) 100986082(ELOVL1) 100995722(ELOVL5)
GGO: 101124844(ELOVL5) 101129175(ELOVL4) 101130310(ELOVL3) 101140898(ELOVL2) 101151646(ELOVL6) 101152434(ELOVL1) 101154080(ELOVL7)
PON: 100173790(ELOVL1) 100174198(ELOVL5) 100440564(ELOVL4) 100454419(ELOVL2) 100456341(ELOVL6) 100460606(ELOVL7) 100461280(ELOVL3)
NLE: 100580650(ELOVL5) 100588402(ELOVL6) 100590122(ELOVL3) 100591430(ELOVL7) 100593990(ELOVL1) 100596130(ELOVL4) 100600368(ELOVL2)
MCC: 692070(ELOVL4) 698870(ELOVL6) 700557(ELOVL1) 703030(ELOVL2) 709866(ELOVL7) 712243(ELOVL5) 712927(ELOVL3)
MCF: 101866566(ELOVL1) 101926474(ELOVL6) 102118797(ELOVL3) 102124038(ELOVL2) 102138130(ELOVL4) 102140887(ELOVL5) 102142519(ELOVL7)
CSAB: 103216428(ELOVL3) 103221342(ELOVL5) 103222048(ELOVL7) 103222171(ELOVL2) 103224964(ELOVL1) 103236116(ELOVL6) 103239978(ELOVL4)
RRO: 104656512(ELOVL3) 104657375(ELOVL2) 104662849(ELOVL5) 104669029(ELOVL1) 104681641(ELOVL7) 104682056(ELOVL4) 104682423(ELOVL6)
RBB: 108512609(ELOVL4) 108515074(ELOVL3) 108515483(ELOVL7) 108519311(ELOVL5) 108535699(ELOVL1) 108541021(ELOVL6) 108541609(ELOVL2)
CJC: 100386025(ELOVL2) 100386849(ELOVL6) 100392386(ELOVL7) 100395729(ELOVL3) 100396385(ELOVL4) 100403530(ELOVL5) 100409750(ELOVL1)
SBQ: 101034271(ELOVL4) 101041837(ELOVL2) 101044283(ELOVL6) 101044551(ELOVL1) 101046575(ELOVL3) 101047560(ELOVL5) 101048081(ELOVL7)
MMU: 12686(Elovl3) 170439(Elovl6) 54325(Elovl1) 54326(Elovl2) 68801(Elovl5) 74559(Elovl7) 83603(Elovl4)
RNO: 102549542 171400(Elovl5) 171402(Elovl6) 309449(Elovl3) 315851(Elovl4) 361895(Elovl7) 498728(Elovl2) 679532(Elovl1)
CGE: 100753555(Elovl5) 100754940(Elovl7) 100763438 100764278(Elovl2) 100767465(Elovl1) 100774317(Elovl3) 100774858(Elovl4)
NGI: 103724484(Elovl7) 103729172(Elovl4) 103732892(Elovl2) 103736929(Elovl5) 103742388(Elovl6) 103743853(Elovl1) 103744016(Elovl3)
HGL: 101699326(Elovl2) 101701805(Elovl4) 101705922(Elovl1) 101710549(Elovl3) 101717423(Elovl5) 101721348(Elovl6) 101725989(Elovl7)
CCAN: 109678157(Elovl2) 109691307(Elovl3) 109694041(Elovl1) 109696848(Elovl5) 109698009(Elovl4) 109700926(Elovl6) 109702323(Elovl7)
OCU: 100342638(ELOVL5) 100344001(ELOVL3) 100350176(ELOVL1) 100352767(ELOVL7) 100353429(ELOVL4) 100358451(ELOVL6) 100358530(ELOVL2)
TUP: 102468519(ELOVL2) 102475313(ELOVL4) 102476603(ELOVL5) 102482262(ELOVL1) 102483326(ELOVL6) 102489276 102490443(ELOVL7) 102494220(ELOVL3)
CFA: 100855761(ELOVL1) 481894(ELOVL4) 486855(ELOVL3) 487900(ELOVL6) 488219(ELOVL2) 608997(ELOVL7) 610377(ELOVL5)
AML: 100465578(ELOVL6) 100465764(ELOVL5) 100472747(ELOVL7) 100472915(ELOVL2) 100474267(ELOVL3) 100475550(ELOVL4) 100476157(ELOVL1)
UMR: 103657419(ELOVL4) 103661747(ELOVL6) 103663654(ELOVL7) 103663993(ELOVL5) 103664917(ELOVL2) 103670810(ELOVL1) 103680399(ELOVL3)
ORO: 101372184(ELOVL1) 101373589(ELOVL5) 101377904(ELOVL6) 101379042(ELOVL2) 101379613(ELOVL4) 101380206(ELOVL3) 101386520(ELOVL7)
FCA: 101082563(ELOVL6) 101086147(ELOVL5) 101093184(ELOVL2) 101097500(ELOVL1) 101098770(ELOVL7) 101101255(ELOVL3) 101101313(ELOVL4)
PTG: 102959362(ELOVL6) 102960047(ELOVL3) 102960399(ELOVL5) 102960657(ELOVL4) 102963086(ELOVL7) 102970388(ELOVL1) 102972782(ELOVL2)
AJU: 106966965(ELOVL3) 106970211(ELOVL1) 106972032(ELOVL2) 106973074(ELOVL5) 106976394(ELOVL7) 106976574(ELOVL4) 106983659(ELOVL6)
BTA: 532015(ELOVL4) 533333(ELOVL6) 539782(ELOVL3) 540348(ELOVL1) 614096(ELOVL7) 615756(ELOVL2) 617293(ELOVL5)
BOM: 102264723(ELOVL7) 102272645(ELOVL5) 102274409(ELOVL2) 102275177(ELOVL3) 102284782(ELOVL4) 102285624(ELOVL6) 102285922(ELOVL1)
BIU: 109556406(ELOVL1) 109558607 109560249(ELOVL6) 109563726(ELOVL4) 109575017(ELOVL7) 109576753(ELOVL2) 109577190(ELOVL5) 109579009(ELOVL3)
PHD: 102316839(ELOVL5) 102320965(ELOVL2) 102322262(ELOVL3) 102324958(ELOVL7) 102329897(ELOVL6) 102340451(ELOVL1) 102340925(ELOVL4)
CHX: 100861282(ELOVL5) 102170380(ELOVL1) 102172444(ELOVL4) 102177113(ELOVL2) 102181762(ELOVL6) 102182633(ELOVL7) 102189456(ELOVL3) 106502144
OAS: 101106896(ELOVL3) 101108431(ELOVL5) 101108515(ELOVL7) 101110801(ELOVL1) 101113417(ELOVL4) 101116613(ELOVL2) 101118274(ELOVL6) 105608607
SSC: 100153368(ELOVL2) 100155434(ELOVL3) 100171403(ELOVL5) 100312969(ELOVL1) 100312970(ELOVL6) 100511670(ELOVL4) 100524592(ELOVL7)
CFR: 102512198(ELOVL4) 102515080(ELOVL3) 102515774(ELOVL5) 102519498(ELOVL7) 102519775(ELOVL1) 102519943(ELOVL2) 102522838(ELOVL6)
CDK: 105084349(ELOVL3) 105084728(ELOVL7) 105089906(ELOVL6) 105090906(ELOVL1) 105099539(ELOVL5) 105102078(ELOVL2) 105104040(ELOVL4)
BACU: 102998571 103001100(ELOVL7) 103006337(ELOVL6) 103006755(ELOVL5) 103007581(ELOVL1) 103008327(ELOVL2) 103011283(ELOVL4) 103019331(ELOVL3)
LVE: 103073053(ELOVL6) 103075618(ELOVL3) 103079296(ELOVL7) 103080456(ELOVL1) 103083406(ELOVL4) 103085369(ELOVL2) 103086524(ELOVL5)
OOR: 101269204(ELOVL1) 101271502(ELOVL3) 101272522(ELOVL7) 101275572(ELOVL5) 101280861(ELOVL2) 101282143(ELOVL6) 101283409(ELOVL4)
ECB: 100051272(ELOVL7) 100053305(ELOVL1) 100060081(ELOVL3) 100063624(ELOVL2) 100069400(ELOVL5) 100069512(ELOVL4) 100072829(ELOVL6)
EPZ: 103541062(ELOVL3) 103542331(ELOVL7) 103544659 103548486(ELOVL4) 103553254(ELOVL5) 103557413(ELOVL1) 103564006(ELOVL6) 103567404(ELOVL2)
EAI: 106824625(ELOVL7) 106829791(ELOVL6) 106833224(ELOVL2) 106837910(ELOVL3) 106837922 106842949(ELOVL4) 106845574(ELOVL5) 106847905(ELOVL1)
MYB: 102242009(ELOVL3) 102245763(ELOVL2) 102246226(ELOVL1) 102250132(ELOVL6) 102251752(ELOVL7) 102255907 102256207(ELOVL4) 102260152(ELOVL5)
MYD: 102756238(ELOVL4) 102758316(ELOVL6) 102762453(ELOVL5) 102763123(ELOVL2) 102763394(ELOVL7) 102768695(ELOVL3) 102770278(ELOVL1)
HAI: 109377448(ELOVL2) 109379485(ELOVL6) 109379595(ELOVL3) 109383409(ELOVL1) 109387807(ELOVL4) 109392870(ELOVL7) 109396355(ELOVL5)
RSS: 109440649 109440745 109440777 109443985(ELOVL3) 109446292(ELOVL4) 109448919(ELOVL5) 109452765(ELOVL6) 109453632(ELOVL7) 109457883(ELOVL1) 109458565(ELOVL2)
PALE: 102878282(ELOVL7) 102880850(ELOVL1) 102883753(ELOVL6) 102885120(ELOVL3) 102891448(ELOVL2) 102895992(ELOVL5) 102897900(ELOVL4)
LAV: 100654940(ELOVL4) 100657711(ELOVL7) 100661059(ELOVL6) 100662376(ELOVL3) 100667896(ELOVL1) 100669438(ELOVL5) 100677669(ELOVL2)
MDO: 100014197(ELOVL5) 100014679(ELOVL1) 100017828(ELOVL4) 100020799(ELOVL6) 100026914(ELOVL2) 100029282(ELOVL3) 100032201(ELOVL7)
SHR: 100916522(ELOVL7) 100920560(ELOVL1) 100922613(ELOVL2) 100923989(ELOVL3) 100927609(ELOVL5) 100928562(ELOVL4) 100932904(ELOVL6)
OAA: 100080155(ELOVL3) 100081381(ELOVL4) 100081938(ELOVL1) 100084190(ELOVL2) 100089631(ELOVL5) 100089956 100682198(ELOVL6)
GGA: 420858(ELOVL2) 421850(ELOVL4) 424564(ELOVL1) 428646(ELOVL5) 428772(ELOVL6) 431579(ELOVL7) 770955(ELOVL3)
MGP: 100538879(ELOVL2) 100539665(ELOVL3) 100539668(ELOVL1) 100540425(ELOVL5) 100542840(ELOVL6) 100546793(ELOVL4) 104914910(ELOVL7)
CJO: 107306023(ELOVL7) 107309660(ELOVL2) 107312020(ELOVL4) 107312117(ELOVL5) 107313601(ELOVL6) 107315876(ELOVL3) 107317407(ELOVL1)
APLA: 101790547(ELOVL4) 101794230(ELOVL1) 101795175(ELOVL7) 101795561(ELOVL5) 101796167(ELOVL6) 101796744(ELOVL2) 101800182 101801566
ACYG: 106029862(ELOVL3) 106030431(ELOVL5) 106034065(ELOVL1) 106035664(ELOVL7) 106038658(ELOVL6) 106041854(ELOVL2) 106048591(ELOVL4)
TGU: 100190615(ELOVL2) 100225083(ELOVL1) 100225997(ELOVL4) 100227813(ELOVL7) 100230721(ELOVL5) 100231220(ELOVL6) 100232706
GFR: 102033945(ELOVL1) 102034097(ELOVL6) 102035472(ELOVL5) 102036402 102039991(ELOVL2) 102040968 102043526(ELOVL7) 102044122(ELOVL4)
FAB: 101810772(ELOVL7) 101811200(ELOVL1) 101813473(ELOVL2) 101814943(ELOVL5) 101815075(ELOVL3) 101819154(ELOVL4) 101819474(ELOVL6) 101819804
PHI: 102102223 102103239(ELOVL1) 102104380(ELOVL5) 102106501(ELOVL2) 102109506(ELOVL7) 102109718 102111803(ELOVL6) 102114272(ELOVL4)
PMAJ: 107198273(ELOVL7) 107201946(ELOVL5) 107202280(ELOVL4) 107203438(ELOVL6) 107205111 107206636(ELOVL3) 107208217(ELOVL1) 107214099(ELOVL2)
CCW: 104686686(ELOVL7) 104691457(ELOVL2) 104692774(ELOVL4) 104693518(ELOVL5) 104695272(ELOVL1) 104696121 104697131(ELOVL6) 104697939(ELOVL3)
FPG: 101916709(ELOVL6) 101916881(ELOVL2) 101918168(ELOVL1) 101919974(ELOVL4) 101920661(ELOVL7) 101921045 101924954(ELOVL5)
FCH: 102048237(ELOVL2) 102049021(ELOVL5) 102049091(ELOVL6) 102052860 102054212(ELOVL1) 102056363(ELOVL4) 102059496(ELOVL7)
CLV: 102083706(ELOVL6) 102091789(ELOVL1) 102093572(ELOVL5) 102095164 102096235(ELOVL7) 102096454(ELOVL2) 102097944(ELOVL4)
EGZ: 104124213 104124799(ELOVL2) 104125516(ELOVL1) 104126226(ELOVL5) 104128372(ELOVL7) 104132758(ELOVL4) 104135536(ELOVL6)
AAM: 106483674(ELOVL2) 106488771 106489580(ELOVL4) 106492101(ELOVL6) 106493256(ELOVL5) 106496820 106498893 106499470(ELOVL1)
ASN: 102370472(ELOVL5) 102373426(ELOVL4) 102374102(ELOVL3) 102378375(ELOVL2) 102387008(ELOVL7) 102388057(ELOVL1) 102388851(ELOVL6)
AMJ: 102560004(ELOVL6) 102561888(ELOVL3) 102566964(ELOVL2) 102571703(ELOVL1) 102573512(ELOVL4) 102574009(ELOVL7) 102574818(ELOVL5)
PSS: 102444349(ELOVL1) 102446236(ELOVL4) 102451620(ELOVL7) 102452886(ELOVL6) 102454353(ELOVL5) 102455762 102457606(ELOVL2) 102463304 112544680
CMY: 102930723(ELOVL2) 102932502 102933307(ELOVL6) 102933860(ELOVL5) 102936627(ELOVL7) 102936820(ELOVL1) 102939512(ELOVL4) 102942417
CPIC: 101935789(ELOVL6) 101936216 101936259 101936469(ELOVL5) 101939130(ELOVL2) 101939673(ELOVL7) 101939683(ELOVL1) 101945122(ELOVL4) 103306322(ELOVL3)
ACS: 100552106(elovl5) 100552766(elovl7) 100555143(elovl6) 100556512(elovl1) 100558520(elovl4) 100558809(elovl2)
PVT: 110073724(ELOVL1) 110073969(ELOVL7) 110080848(ELOVL2) 110085734(ELOVL4) 110087290(ELOVL6) 110090240(ELOVL5) 110091506
PBI: 103053806(ELOVL4) 103054730(ELOVL7) 103057461(ELOVL1) 103059591(ELOVL5) 103059597(ELOVL2) 103061749(ELOVL6)
GJA: 107106450(ELOVL1) 107111768(ELOVL2) 107111936(ELOVL7) 107121119(ELOVL5) 107121888(ELOVL4) 107122700(ELOVL6)
XLA: 108696247 108697499 108704446(elovl2.S) 108706706 108710167(elovl6) 108717990 379510(elovl1.L) 380063(elovl1.S) 398440(elovl7.L) 432300(elovl7.S) 447388(elovl2.L) 734428 734710(elovl5.L) 734950(elovl5.S)
XTR: 100496222(elovl4) 100497108(elovl3) 101731836 101732387 101733189 448054(elovl7) 496694(elovl5) 548913(elovl2) 549398(elovl1) 550011(elovl6)
NPR: 108785501 108788207(ELOVL7) 108788457(ELOVL2) 108788957(ELOVL5) 108791172(ELOVL1) 108798148(ELOVL6) 108798588(ELOVL4) 108799010
DRE: 317738(elovl6) 327274(elovl7b) 334217(elovl7a) 335732(elovl4b) 393425(elovl5) 393769(elovl4a) 406725(elovl1b) 554145(elovl8b) 678614(elovl2)
IPU: 100528278(elovl6) 100528280(elov7) 100528842(elovl5) 108256217(elovl2) 108265939 108265965(elovl7) 108270818 108272628(elovl4) 108274257 108275555(ELOVL4) 108277391 108280856
SFM: 108923705 108927542(elovl2) 108929205 108932843(elovl5) 108934869 108935055 108937440(elovl4) 108938672(elovl7) 108938677(elovl6)
LCM: 102345269(ELOVL1) 102345809(ELOVL5) 102346876 102346933(ELOVL2) 102348556(ELOVL6) 102349419(ELOVL7) 102351492(ELOVL3) 102364316(ELOVL4)
CMK: 103174616(elovl1) 103177806(elovl7) 103179003(elovl5) 103180891(elovl6) 103181830 103182716 103182793 103184556(elovl2) 103186183(elovl4)
DME: Dmel_CG11801(Elo68beta) Dmel_CG17821(CG17821) Dmel_CG18609(CG18609) Dmel_CG32072(Elo68alpha) Dmel_CG3971(Baldspot)
DSI: Dsimw501_GD12451(Dsim_GD12451) Dsimw501_GD12826(Dsim_GD12826) Dsimw501_GD12827(Dsim_GD12827) Dsimw501_GD25362(Dsim_GD25362) Dsimw501_GD25363(Dsim_GD25363)
NVI: 100116202
CEL: CELE_F41H10.7(elo-5) CELE_F41H10.8(elo-6)
CBR: CBG19953(Cbr-elo-6) CBG19955(Cbr-elo-5)
EGL: EGR_06613
ATH: AT1G01120(KCS1) AT1G04220(KCS2) AT1G07720(KCS3) AT1G19440(KCS4) AT1G25450(KCS5) AT1G68530(KCS6) AT1G71160(KCS7) AT2G15090(KCS8) AT2G16280(KCS9) AT2G26250(KCS10) AT2G26640(KCS11) AT2G28630(KCS12) AT2G46720(KCS13) AT3G10280(KCS14) AT3G52160(KCS15) AT4G34250(KCS16) AT4G34510(KCS17) AT4G34520(KCS18) AT5G04530(KCS19) AT5G43760(KCS20) AT5G49070(KCS21)
GRA: 105763956(KCS10) 105767824(KCS6) 105767937(KCS7) 105769069(KCS16) 105773004(KCS) 105773012(KCS) 105773018 105773030(KCS9) 105773267(KCS11) 105774619(KCS15) 105774963(KCS) 105777885(KCS) 105778000(KCS) 105778065(KCS2) 105780861(KCS20) 105782907(KCS8) 105784862 105786120(KCS13) 105791025(KCS3) 105791513(KCS) 105792878(KCS19) 105793790(KCS) 105794738(KCS5) 105795309(KCS4) 105795517(KCS17) 105798726(KCS) 105798781 105800565(KCS1) 105801762(KCS21)
LJA: Lj0g3v0065089.1(Lj0g3v0065089.1) Lj0g3v0078429.1(Lj0g3v0078429.1) Lj0g3v0216389.1(Lj0g3v0216389.1) Lj0g3v0220359.1(Lj0g3v0220359.1) Lj0g3v0241719.1(Lj0g3v0241719.1) Lj0g3v0246159.1(Lj0g3v0246159.1) Lj0g3v0324009.1(Lj0g3v0324009.1) Lj1g3v1798580.1(Lj1g3v1798580.1) Lj1g3v1914960.1(Lj1g3v1914960.1) Lj1g3v2296500.1(Lj1g3v2296500.1) Lj1g3v4667830.1(Lj1g3v4667830.1) Lj1g3v5060470.1(Lj1g3v5060470.1) Lj2g3v0856560.1(Lj2g3v0856560.1) Lj2g3v1154110.1(Lj2g3v1154110.1) Lj2g3v1199860.1(Lj2g3v1199860.1) Lj3g3v0170770.1(Lj3g3v0170770.1) Lj3g3v3363310.1(Lj3g3v3363310.1) Lj4g3v1812470.1(Lj4g3v1812470.1) Lj4g3v1812470.2(Lj4g3v1812470.2) Lj5g3v0106070.1(Lj5g3v0106070.1) Lj5g3v1207760.1(Lj5g3v1207760.1) Lj5g3v1207770.1(Lj5g3v1207770.1) Lj5g3v1207790.1(Lj5g3v1207790.1) Lj5g3v2203980.1(Lj5g3v2203980.1) Lj5g3v2288650.1(Lj5g3v2288650.1) Lj5g3v2288650.2(Lj5g3v2288650.2) Lj5g3v2288660.1(Lj5g3v2288660.1) Lj6g3v0000150.1(Lj6g3v0000150.1) Lj6g3v0000160.1(Lj6g3v0000160.1) Lj6g3v0000180.1(Lj6g3v0000180.1) Lj6g3v1464000.1(Lj6g3v1464000.1) Lj6g3v2019780.1(Lj6g3v2019780.1)
DOSA: Os01t0529800-01(Os01g0529800) Os02t0205500-01(Os02g0205500) Os02t0731900-01(Os02g0731900) Os02t0813600-01(Os02g0813600) Os03t0162650-01(Os03g0162650) Os03t0162800-01(Os03g0162800) Os03t0181500-01(Os03g0181500) Os03t0220100-01(Os03g0220100) Os03t0245700-02(Os03g0245700) Os03t0382100-01(Os03g0382100) Os03t0383600-01(Os03g0383600) Os04t0116800-01(Os04g0116800) Os05t0568000-02(Os05g0568000) Os05t0574600-01(Os05g0574600) Os06t0260500-00(Os06g0260500) Os06t0262800-01(Os06g0262800) Os06t0598800-01(Os06g0598800) Os09t0360500-01(Os09g0360500) Os09t0521100-01(Os09g0521100) Os10t0416200-01(Os10g0416200) Os10t0472900-01(Os10g0472900) Os11t0591200-01(Os11g0591200)
ATS: 109731451(LOC109731451) 109733085(LOC109733085) 109733087(LOC109733087) 109733089(LOC109733089) 109733090(LOC109733090) 109733887(LOC109733887) 109739633(LOC109739633) 109739723(LOC109739723) 109740860(LOC109740860) 109743970(LOC109743970) 109745323(LOC109745323) 109745610(LOC109745610) 109746289(LOC109746289) 109746362(LOC109746362) 109747063(LOC109747063) 109747064(LOC109747064) 109747065(LOC109747065) 109748079(LOC109748079) 109748104(LOC109748104) 109749894(LOC109749894) 109750508(LOC109750508) 109751555(LOC109751555) 109751979(LOC109751979) 109753288(LOC109753288) 109753289(LOC109753289) 109758154(LOC109758154) 109758728(LOC109758728) 109758786(LOC109758786) 109759919(LOC109759919) 109760347(LOC109760347) 109761369(LOC109761369) 109761926(LOC109761926) 109764188(LOC109764188) 109764389(LOC109764389) 109764691(LOC109764691) 109764815(LOC109764815) 109766471(LOC109766471) 109767526(LOC109767526) 109768171(LOC109768171) 109768181(LOC109768181) 109770245(LOC109770245) 109770408(LOC109770408) 109770596(LOC109770596) 109773270(LOC109773270) 109774309(LOC109774309) 109774334(LOC109774334) 109776044(LOC109776044) 109776861(LOC109776861) 109777071(LOC109777071) 109781205(LOC109781205) 109781475(LOC109781475) 109782561(LOC109782561) 109783633(LOC109783633) 109787337(LOC109787337)
SCE: YCR034W(ELO2) YJL196C(ELO1) YLR372W(ELO3)
KMX: KLMA_10159(FEN1) KLMA_50271(SUR4)
NCS: NCAS_0A02340(NCAS0A02340) NCAS_0B08500(NCAS0B08500) NCAS_0J01280(NCAS0J01280)
NDI: NDAI_0A00730(NDAI0A00730) NDAI_0D04530(NDAI0D04530) NDAI_0J02040(NDAI0J02040)
TPF: TPHA_0A02570(TPHA0A02570) TPHA_0B02400(TPHA0B02400)
TBL: TBLA_0I02760(TBLA0I02760) TBLA_0J01230(TBLA0J01230)
TDL: TDEL_0C05610(TDEL0C05610) TDEL_0E01530(TDEL0E01530)
KAF: KAFR_0A06140(KAFR0A06140) KAFR_0G00130(KAFR0G00130) KAFR_0G00240(KAFR0G00240)
CAL: CAALFM_C112790CA(FEN1)
NCR: NCU06694
NTE: NEUTE1DRAFT75853(NEUTE1DRAFT_75853)
MGR: MGG_07280
SSCK: SPSK_05380
MAW: MAC_05925
MAJ: MAA_07869
CMT: CCM_03752
MBE: MBM_08440
ANG: ANI_1_1400024(An02g09910)
ABE: ARB_06714
TVE: TRV_04055
PTE: PTT_07837
DFA: DFA_00445 DFA_08982(cutA)
SMIN: v1.2.033476.t1(symbB.v1.2.033476.t1)
TCR: 506661.30
 » show all
Taxonomy
Reference
1  [PMID:8702485]
  Authors
Toke DA, Martin CE
  Title
Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae.
  Journal
J Biol Chem 271:18413-22 (1996)
DOI:10.1074/jbc.271.31.18413
  Sequence
[sce:YJL196C]
Reference
2  [PMID:9211877]
  Authors
Oh CS, Toke DA, Mandala S, Martin CE.
  Title
ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in  fatty acid elongation and are required for sphingolipid formation.
  Journal
J Biol Chem 272:17376-84 (1997)
DOI:10.1074/jbc.272.28.17376
  Sequence
Reference
3  [PMID:9546663]
  Authors
Dittrich F, Zajonc D, Huhne K, Hoja U, Ekici A, Greiner E, Klein H, Hofmann J, Bessoule JJ, Sperling P, Schweizer E
  Title
Fatty acid elongation in yeast--biochemical characteristics of the enzyme system  and isolation of elongation-defective mutants.
  Journal
Eur J Biochem 252:477-85 (1998)
DOI:10.1046/j.1432-1327.1998.2520477.x
  Sequence
[sce:YJL196C]
Reference
4  [PMID:10330468]
  Authors
Millar AA, Clemens S, Zachgo S, Giblin EM, Taylor DC, Kunst L
  Title
CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme.
  Journal
Plant Cell 11:825-38 (1999)
  Sequence
[ath:AT1G68530]
Reference
5  [PMID:12135493]
  Authors
Ghanevati M, Jaworski JG
  Title
Engineering and mechanistic studies of the Arabidopsis FAE1 beta-ketoacyl-CoA synthase, FAE1 KCS.
  Journal
Eur J Biochem 269:3531-9 (2002)
DOI:10.1046/j.1432-1033.2002.03039.x
Reference
6  [PMID:16765910]
  Authors
Blacklock BJ, Jaworski JG
  Title
Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases.
  Journal
Biochem Biophys Res Commun 346:583-90 (2006)
DOI:10.1016/j.bbrc.2006.05.162
  Sequence
Reference
7  [PMID:17719544]
  Authors
Denic V, Weissman JS
  Title
A molecular caliper mechanism for determining very long-chain fatty acid length.
  Journal
Cell 130:663-77 (2007)
DOI:10.1016/j.cell.2007.06.031
Reference
8  [PMID:22284369]
  Authors
Tresch S, Heilmann M, Christiansen N, Looser R, Grossmann K
  Title
Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases.
  Journal
Phytochemistry 76:162-71 (2012)
DOI:10.1016/j.phytochem.2011.12.023
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.199
IUBMB Enzyme Nomenclature: 2.3.1.199
ExPASy - ENZYME nomenclature database: 2.3.1.199
BRENDA, the Enzyme Database: 2.3.1.199

DBGET integrated database retrieval system