KEGG   ENZYME: 2.3.1.42Help
Entry
EC 2.3.1.42                 Enzyme                                 

Name
glycerone-phosphate O-acyltransferase;
dihydroxyacetone phosphate acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:glycerone-phosphate O-acyltransferase
Reaction(IUBMB)
acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate [RN:R01013]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
glycerone phosphate [CPD:C00111]
Product
CoA [CPD:C00010];
acylglycerone phosphate [CPD:C03372]
Comment
A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA.
History
EC 2.3.1.42 created 1972
Pathway
ec00564  Glycerophospholipid metabolism
Orthology
K00649  glyceronephosphate O-acyltransferase
K13507  glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase
Genes
HSA: 8443(GNPAT)
PTR: 741681(GNPAT)
PPS: 100994430(GNPAT)
GGO: 101145496(GNPAT)
PON: 100172931(GNPAT)
NLE: 100579846(GNPAT)
MCC: 713603(GNPAT)
MCF: 101925593(GNPAT)
CSAB: 103230751(GNPAT)
RRO: 104670714(GNPAT)
RBB: 108537840(GNPAT)
CJC: 100414247(GNPAT)
SBQ: 101041808(GNPAT)
MMU: 14712(Gnpat)
RNO: 84470(Gnpat)
CGE: 100765024(Gnpat)
NGI: 103744131(Gnpat)
HGL: 101712069(Gnpat)
CCAN: 109694600(Gnpat)
OCU: 100353451(GNPAT)
TUP: 102468980(GNPAT)
CFA: 479204(GNPAT)
AML: 100472094(GNPAT)
UMR: 103661874(GNPAT)
ORO: 101376734(GNPAT)
FCA: 101090468(GNPAT)
PTG: 102968870(GNPAT)
AJU: 106981646(GNPAT)
BTA: 538800(GNPAT)
BOM: 102286073(GNPAT)
PHD: 102335365(GNPAT)
CHX: 102174721(GNPAT)
OAS: 101111422(GNPAT)
SSC: 100156253(GNPAT)
CFR: 102522815(GNPAT)
CDK: 105102149(GNPAT)
BACU: 103006358(GNPAT)
LVE: 103085307(GNPAT)
OOR: 101283114(GNPAT)
ECB: 100060758(GNPAT)
EPZ: 103553993(GNPAT)
EAI: 106846717(GNPAT)
MYB: 102255922(GNPAT)
MYD: 102753196(GNPAT)
HAI: 109395072(GNPAT)
RSS: 109461261(GNPAT)
PALE: 102894429(GNPAT)
LAV: 100671847(GNPAT)
TMU: 101361755
MDO: 100029521(GNPAT)
SHR: 100934097(GNPAT)
OAA: 100085042
GGA: 421548(GNPAT)
MGP: 100543913(GNPAT)
CJO: 107311436(GNPAT)
APLA: 101799745(GNPAT)
ACYG: 106044570(GNPAT)
TGU: 100224202(GNPAT)
GFR: 102044351(GNPAT)
FAB: 101815390(GNPAT)
PHI: 102103719(GNPAT)
PMAJ: 107201920(GNPAT)
CCAE: 111927077(GNPAT)
CCW: 104684319(GNPAT)
FPG: 101921172(GNPAT)
FCH: 102049765(GNPAT)
CLV: 102090227(GNPAT)
EGZ: 104131069(GNPAT)
AAM: 106487366(GNPAT)
ASN: 102387492(GNPAT)
AMJ: 102573444(GNPAT)
PSS: 102447254(GNPAT)
CMY: 102940346(GNPAT)
CPIC: 101948121(GNPAT)
ACS: 100562202(gnpat)
PVT: 110083064(GNPAT)
PBI: 103063911(GNPAT)
GJA: 107113461(GNPAT)
XLA: 100158402(gnpat.S) 108700390 444573
XTR: 100494829 733943(gnpat)
DRE: 572335(gnpat)
IPU: 108257502 108260471(gnpat)
AMEX: 103026328(gnpat) 103043282
TRU: 101062802(gnpat) 101072796
LCO: 104923569 104932463(gnpat)
NCC: 104958965(gnpat) 104962070
OLA: 101155817(gnpat) 101166180
XMA: 102217607(gnpat) 102223376
PRET: 103457317(gnpat) 103457687
NFU: 107377758(gnpat) 107395976
CSEM: 103381071 103381134(gnpat)
SDU: 111216410 111239366(gnpat)
HCQ: 109516735 109523524(gnpat)
BPEC: 110153837 110164113(gnpat)
OTW: 112239009 112250169(gnpat)
SFM: 108923986 108928536(gnpat)
LCM: 102366515(GNPAT)
CMK: 103180557(gnpat)
CIN: 100178961
SPU: 590838
APLC: 110990116
SKO: 102808986
DME: Dmel_CG4625(Dhap-at)
DSI: Dsimw501_GD18193(Dsim_GD18193)
MDE: 101897697
AAG: 5576748
AME: 412563
BIM: 100745376
BTER: 100646321
SOC: 105199621
AEC: 105151630
ACEP: 105617458
PBAR: 105428473
HST: 105180680
DQU: 106742466
CFO: 105252352
LHU: 105675563
PGC: 109852203
PCF: 106791381
NVI: 100115025
MDL: 103571774
TCA: 660119
DPA: 109543825
NVL: 108560511
BMOR: 101744539
PMAC: 106721520
PRAP: 110993079
HAW: 110380443
PXY: 105380393
API: 100573870
CLEC: 106666885
ZNE: 110836717
FCD: 110843586
TUT: 107372017
CEL: CELE_Y46G5A.21(acl-7)
CBR: CBG18430(Cbr-acl-7)
BMY: Bm1_40215
CRG: 105348074
MYI: 110455534
EPA: 110235657
ADF: 107357049
HMG: 100205381
AQU: 100640070
SCE: YBL011W(SCT1) YKR067W(GPT2)
KMX: KLMA_30247(GPT2) KLMA_30327(SCT1)
NCS: NCAS_0B06810(NCAS0B06810) NCAS_0C05390(NCAS0C05390)
NDI: NDAI_0A03280(NDAI0A03280) NDAI_0H00720(NDAI0H00720)
TPF: TPHA_0J01260(TPHA0J01260) TPHA_0K01680(TPHA0K01680)
TBL: TBLA_0C04170(TBLA0C04170) TBLA_0J00910(TBLA0J00910)
TDL: TDEL_0B02750(TDEL0B02750) TDEL_0F02510(TDEL0F02510)
KAF: KAFR_0H00490(KAFR0H00490) KAFR_0I01020(KAFR0I01020)
SLB: AWJ20_1421(SCT1)
NCR: NCU05985
NTE: NEUTE1DRAFT132129(NEUTE1DRAFT_132129)
MGR: MGG_01291
SSCK: SPSK_07062
MAW: MAC_02640
MAJ: MAA_02162
CMT: CCM_05062
MBE: MBM_01050
ANI: AN5599.2
ANG: ANI_1_490124(An14g03360)
ABE: ARB_02331
TVE: TRV_04690
PTE: PTT_06646
CNE: CNC02160
CNB: CNBC5070
ABP: AGABI1DRAFT126773(AGABI1DRAFT_126773) AGABI1DRAFT34488(AGABI1DRAFT_34488) AGABI1DRAFT61355(AGABI1DRAFT_61355)
ABV: AGABI2DRAFT117770(AGABI2DRAFT_117770) AGABI2DRAFT228041(AGABI2DRAFT_228041) AGABI2DRAFT64815(AGABI2DRAFT_64815)
MGL: MGL_2378
DFA: DFA_05553
PYO: PY17X_1430600(PY06015)
PCB: PCHAS_143030(PC000822.04.0)
SMIN: v1.2.008197.t1(symbB.v1.2.008197.t1)
PTI: PHATRDRAFT_54709(GPT1)
LMA: LMJF_03_0080(GAT) LMJF_34_1090(DAT)
LIF: LINJ_03_0070(GAT) LINJ_34_1170(DAT)
 » show all
Taxonomy
Reference
1  [PMID:6271231]
  Authors
Ballas LM, Bell RM.
  Title
Topography of glycerolipid synthetic enzymes. Synthesis of phosphatidylserine, phosphatidylinositol and glycerolipid intermediates occurs on the cytoplasmic surface of rat liver microsomal vesicles.
  Journal
Biochim Biophys Acta 665:586-95 (1981)
DOI:10.1016/0005-2760(81)90274-5
Reference
2  [PMID:6746639]
  Authors
Declercq PE, Haagsman HP, Van Veldhoven P, Debeer LJ, Van Golde LM, Mannaerts GP.
  Title
Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis.
  Journal
J Biol Chem 259:9064-75 (1984)
Reference
3  [PMID:5656381]
  Authors
Hajra AK.
  Title
Biosynthesis of acyl dihydroxyacetone phosphate in guinea pig liver mitochondria.
  Journal
J Biol Chem 243:3458-65 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.42
IUBMB Enzyme Nomenclature: 2.3.1.42
ExPASy - ENZYME nomenclature database: 2.3.1.42
BRENDA, the Enzyme Database: 2.3.1.42
CAS: 37257-19-5

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