KEGG   ENZYME: 2.3.1.45Help
Entry
EC 2.3.1.45                 Enzyme                                 

Name
N-acetylneuraminate 7-O(or 9-O)-acetyltransferase;
N-acetylneuraminate 7(8)-O-acetyltransferase;
sialate O-acetyltransferase;
N-acetylneuraminate 7,8-O-acetyltransferase;
acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase;
acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase;
glycoprotein 7(9)-O-acetyltransferase;
acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase;
N-acetylneuraminate O7-(or O9-)acetyltransferase;
acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-7-O(or 9-O)-acetylneuraminate [RN:R01807 R01808]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
N-acetylneuraminate [CPD:C00270]
Product
CoA [CPD:C00010];
N-acetyl-7-O-acetylneuraminate [CPD:C04016];
N-acetyl-9-O-acetylneuraminate [CPD:C04017]
Comment
Both free and glycosidically bound N-acetyl- and N-glycolylneuraminates can act as O-acetyl acceptors.
History
EC 2.3.1.45 created 1972
Orthology
K03377  N-acetylneuraminate 9-O-acetyltransferase
Genes
HSA: 64921(CASD1)
PTR: 463543(CASD1)
PPS: 100974499(CASD1)
GGO: 101143379(CASD1)
PON: 100438741(CASD1)
NLE: 100598487(CASD1)
MCC: 700222(CASD1)
MCF: 101867425(CASD1)
CSAB: 103226535(CASD1)
RRO: 104682782(CASD1)
RBB: 108517183(CASD1)
CJC: 100411081(CASD1)
SBQ: 101031614(CASD1)
MMU: 213819(Casd1)
RNO: 678772(Casd1)
CGE: 100766850(Casd1)
NGI: 103725223(Casd1)
HGL: 101722739(Casd1)
CCAN: 109701308(Casd1)
OCU: 100352588(CASD1)
TUP: 102497173(CASD1)
CFA: 475232(CASD1)
AML: 100476885(CASD1)
UMR: 103658798(CASD1)
ORO: 101374359(CASD1)
FCA: 101094006(CASD1)
PTG: 102966512(CASD1)
AJU: 106969952(CASD1)
BTA: 532541(CASD1)
BOM: 102268785(CASD1)
BIU: 109558216(CASD1)
PHD: 102330884(CASD1)
CHX: 102186927(CASD1)
OAS: 101114863(CASD1)
SSC: 100521674(CASD1)
CFR: 102522624(CASD1)
CDK: 105088731(CASD1)
BACU: 103006473(CASD1)
LVE: 103069901(CASD1)
OOR: 101289219(CASD1)
ECB: 100062437(CASD1)
EPZ: 103553630(CASD1)
EAI: 106838932(CASD1)
MYB: 102252428(CASD1)
MYD: 102761672(CASD1)
HAI: 109371941(CASD1)
RSS: 109440379 109446390(CASD1)
PALE: 102880254(CASD1)
LAV: 100676405(CASD1)
TMU: 101340759
MDO: 100032269(CASD1)
SHR: 100916306(CASD1)
GGA: 420565(CASD1)
MGP: 100540591(CASD1)
CJO: 107309084(CASD1)
APLA: 101800215(CASD1)
ACYG: 106039663(CASD1)
TGU: 100222894(CASD1)
GFR: 102033654(CASD1)
FAB: 101810789(CASD1)
PHI: 102100408(CASD1)
PMAJ: 107199998(CASD1)
CCAE: 111924230(CASD1)
CCW: 104689166(CASD1)
FPG: 101921816(CASD1)
FCH: 102046861(CASD1)
CLV: 102090215(CASD1)
EGZ: 104129019(CASD1)
AAM: 106483396(CASD1)
ASN: 102372728(CASD1)
AMJ: 102569055(CASD1)
PSS: 102457331(CASD1)
CMY: 102939537(CASD1)
CPIC: 101934247(CASD1)
ACS: 100560188(casd1)
PVT: 110074747(CASD1)
PBI: 103053522(CASD1)
GJA: 107117998(CASD1)
XLA: 108718841(casd1.L) 108719904(casd1.S)
XTR: 100216199(casd1)
NPR: 108790505(CASD1)
DRE: 692268(casd1)
SGH: 107591593 107593528(casd1)
CCAR: 109063401(casd1) 109103049
IPU: 108257082(casd1)
AMEX: 103024597(casd1)
TRU: 101070985(casd1)
LCO: 104922871(casd1)
NCC: 104961900(casd1)
MZE: 101485804(casd1)
OLA: 101169373(casd1)
XMA: 102231942(casd1)
PRET: 103472237(casd1)
NFU: 107383296(casd1)
KMR: 108239299(casd1)
CSEM: 103394117(casd1)
LCF: 108876906(casd1)
SDU: 111223046(casd1)
HCQ: 109527681(casd1)
MALB: 109968109(casd1) 109968180
SASA: 106570464 106588938(casd1)
ELS: 105022786(casd1)
SFM: 108922005(casd1)
LCM: 102345636(CASD1)
CMK: 103189016(casd1)
CIN: 100177911(casd1)
DME: Dmel_CG2938(CG2938)
DER: 6550885
DSI: Dsimw501_GD16317(Dsim_GD16317)
DWI: 6638069
MDE: 101896007
AAG: 5565042
AME: 411555
BIM: 100747938
BTER: 100648596
SOC: 105198766
AEC: 105148741
ACEP: 105618612
PBAR: 105422067
HST: 105191814
DQU: 106750961
CFO: 105251781
LHU: 105675610
PGC: 109854082
PCF: 106788211
MDL: 103580488
TCA: 655926
DPA: 109536156
NVL: 108563604
BMOR: 101738522
PMAC: 106709137
PRAP: 111003476
HAW: 110380934
API: 100160184
CLEC: 106667427
ZNE: 110831637
FCD: 110851952
TUT: 107364854
CRG: 105319248
MYI: 110461094
OBI: 106868097
SHX: MS3_07956
EGL: EGR_01772
AQU: 109588945
ATH: AT2G34410(RWA3) AT3G06550(RWA2) AT5G46340(RWA1)
LJA: Lj4g3v0281140.1(Lj4g3v0281140.1) Lj4g3v0281140.2(Lj4g3v0281140.2) Lj4g3v0281140.3(Lj4g3v0281140.3) Lj4g3v2253590.1(Lj4g3v2253590.1) Lj4g3v2253590.2(Lj4g3v2253590.2)
DOSA: Os01t0631100-01(Os01g0631100) Os03t0314200-01(Os03g0314200) Os05t0582100-01(Os05g0582100)
ATS: 109752464(LOC109752464) 109764228(LOC109764228) 109778378(LOC109778378)
CRE: CHLREDRAFT_190979(OAT1)
MNG: MNEG_3646
APRO: F751_5169
MGR: MGG_04984
SSCK: SPSK_06967
MBE: MBM_10036
CNE: CNN01530
CNB: CNBN1490
MRR: Moror_940
ABP: AGABI1DRAFT66224(AGABI1DRAFT_66224)
ABV: AGABI2DRAFT198117(AGABI2DRAFT_198117)
SMIN: v1.2.029763.t1(symbB.v1.2.029763.t1)
 » show all
Taxonomy
Reference
1  [PMID:5446640]
  Authors
Schauer R.
  Title
[Biosynthesis of N-acetyl-O-acetylneuraminic acids. I. Incorporation of (14C) acetate into sections of the submaxillary salivary gland of ox and horse]
  Journal
Hoppe Seylers Z Physiol Chem 351:595-602 (1970)
Reference
2  [PMID:5425947]
  Authors
Schauer R.
  Title
[Biosynthesis of N-acetyl-O-acetylneuraminic acids. II. Substrate and intracellular localization of bovine acetyl-coenzyme A: N-acetylneuraminate-7- and 8-O-acetyltransferase]
  Journal
Hoppe Seylers Z Physiol Chem 351:749-58 (1970)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.45
IUBMB Enzyme Nomenclature: 2.3.1.45
ExPASy - ENZYME nomenclature database: 2.3.1.45
BRENDA, the Enzyme Database: 2.3.1.45
CAS: 9054-50-6

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