KEGG   ENZYME: 2.3.1.7Help
Entry
EC 2.3.1.7                  Enzyme                                 

Name
carnitine O-acetyltransferase;
acetyl-CoA-carnitine O-acetyltransferase;
acetylcarnitine transferase;
carnitine acetyl coenzyme A transferase;
carnitine acetylase;
carnitine acetyltransferase;
carnitine-acetyl-CoA transferase;
CATC
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:carnitine O-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + carnitine = CoA + O-acetylcarnitine [RN:R02396]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
carnitine [CPD:C00487]
Product
CoA [CPD:C00010];
O-acetylcarnitine [CPD:C02571]
Comment
Also acts on propanoyl-CoA and butanoyl-CoA (cf. EC 2.3.1.21 carnitine O-palmitoyltransferase and EC 2.3.1.137 carnitine O-octanoyltransferase).
History
EC 2.3.1.7 created 1961
Orthology
K00624  carnitine O-acetyltransferase
Genes
HSA: 1384(CRAT)
PTR: 107976794(CRAT)
PPS: 100983113(CRAT)
GGO: 101151473(CRAT)
PON: 100459793(CRAT)
NLE: 100600480(CRAT)
MCC: 716908(CRAT)
MCF: 102131038(CRAT)
CSAB: 103239775(CRAT)
RRO: 104660525(CRAT)
RBB: 108512828(CRAT)
CJC: 100391765(CRAT)
SBQ: 101031637(CRAT)
MMU: 12908(Crat)
RNO: 311849(Crat)
CGE: 100762198(Crat)
NGI: 103727904(Crat)
HGL: 101706994(Crat)
CCAN: 109693449(Crat)
OCU: 100344633(CRAT)
TUP: 102486617(CRAT)
CFA: 491304(CRAT)
AML: 100464724(CRAT)
UMR: 103670426(CRAT)
ORO: 101378681(CRAT)
FCA: 101084660(CRAT)
PTG: 102957190(CRAT)
AJU: 106966300(CRAT)
BTA: 512902(CRAT)
BOM: 102270070(CRAT)
BIU: 109566534(CRAT)
PHD: 102331064(CRAT)
CHX: 102170433(CRAT)
OAS: 101105648(CRAT)
SSC: 100127351(CRAT)
CFR: 102506902(CRAT)
CDK: 105092550(CRAT)
BACU: 103005902(CRAT)
LVE: 103076896(CRAT)
OOR: 101287380(CRAT)
ECB: 100070062(CRAT)
EPZ: 103563039(CRAT)
EAI: 106845413(CRAT)
MYB: 102243520(CRAT)
MYD: 102766836(CRAT)
HAI: 109382273(CRAT)
RSS: 109445920(CRAT)
PALE: 102892367(CRAT)
LAV: 100657234(CRAT)
TMU: 101359621
MDO: 100012605(CRAT)
SHR: 100926707(CRAT)
GGA: 417195(CRAT)
MGP: 100547341(CRAT)
CJO: 107307009 107321742(CRAT)
APLA: 101791336(CRAT)
ACYG: 106047293(CRAT)
TGU: 100231079(CRAT)
GFR: 102043953(CRAT)
FAB: 101812779(CRAT)
PHI: 102111280(CRAT)
PMAJ: 107212018(CRAT)
CCAE: 111936988(CRAT)
CCW: 104688289(CRAT)
FPG: 101911093(CRAT)
FCH: 102053571(CRAT)
CLV: 102084317(CRAT)
EGZ: 104122444(CRAT)
AAM: 106490296(CRAT) 106493517
ASN: 102382269 102384032(CRAT)
AMJ: 102573756 106736861(CRAT)
PSS: 102448497(CRAT)
CMY: 102947827(CRAT)
CPIC: 101944462(CRAT) 101949514
ACS: 100556956 100566780(crat)
GJA: 107110604(CRAT) 107118457
XLA: 108698557 108704695(crat.1.L) 443922(crat.2.S)
XTR: 394811(crat.2) 613081(crat.1)
NPR: 108786526 108799029(CRAT)
DRE: 447855(cratb) 449545(crata)
IPU: 108260314(crat) 108265337 108274804(CRAT)
LCM: 102355603 102359761(CRAT)
CMK: 103184686(crat)
CIN: 104266596
SPU: 593866
APLC: 110975820
DME: Dmel_CG1041(CRAT) Dmel_CG5122(CG5122) Dmel_CG5265(CG5265)
DSI: Dsimw501_GD19146(Dsim_GD19146) Dsimw501_GD19548(Dsim_GD19548) Dsimw501_GD23864(Dsim_GD23864)
AAG: 5574713
SOC: 105195421
AEC: 105151029
ACEP: 105619793
PBAR: 105424980
HST: 105181524
DQU: 106746799
CFO: 105258575
PGC: 109853868
PCF: 106792776
NVI: 100118112
TCA: 659316
BMOR: 101742645
PMAC: 106710708
PRAP: 110998636
HAW: 110375431
CLEC: 106668800
ZNE: 110833896
FCD: 110844751
CEL: CELE_B0395.3(B0395.3)
CBR: CBG16408
CRG: 105333701
MYI: 110441945
OBI: 106879638
ADF: 107344460
AQU: 100634360
SCE: YAR035W(YAT1) YER024W(YAT2) YML042W(CAT2)
KMX: KLMA_10186(YAT1) KLMA_30654(CAT2) KLMA_60439(YAT2)
NCS: NCAS_0A15010(NCAS0A15010) NCAS_0H02500(NCAS0H02500) NCAS_0I01840(NCAS0I01840)
NDI: NDAI_0A06420(NDAI0A06420) NDAI_0C01130(NDAI0C01130) NDAI_0J00460(NDAI0J00460)
TPF: TPHA_0E02020(TPHA0E02020) TPHA_0I03070(TPHA0I03070) TPHA_0P00570(TPHA0P00570)
TBL: TBLA_0A06860(TBLA0A06860) TBLA_0F02910(TBLA0F02910) TBLA_0G00830(TBLA0G00830)
TDL: TDEL_0A03760(TDEL0A03760) TDEL_0D04470(TDEL0D04470) TDEL_0H00610(TDEL0H00610)
KAF: KAFR_0B00530(KAFR0B00530) KAFR_0C05330(KAFR0C05330) KAFR_0F02280(KAFR0F02280)
SLB: AWJ20_1056(CAT2) AWJ20_3310(YAT1)
NTE: NEUTE1DRAFT145504(NEUTE1DRAFT_145504) NEUTE1DRAFT45753(NEUTE1DRAFT_45753)
BFU: BCIN_03g07910(Bccat2)
ANG: ANI_1_192164(An18g01590) ANI_1_724074(An08g04990)
ABP: AGABI1DRAFT111693(AGABI1DRAFT_111693) AGABI1DRAFT112064(AGABI1DRAFT_112064) AGABI1DRAFT113708(AGABI1DRAFT_113708) AGABI1DRAFT76491(AGABI1DRAFT_76491)
ABV: AGABI2DRAFT179138(AGABI2DRAFT_179138) AGABI2DRAFT193306(AGABI2DRAFT_193306) AGABI2DRAFT200564(AGABI2DRAFT_200564) AGABI2DRAFT66041(AGABI2DRAFT_66041)
MGL: MGL_3429
VTA: B0190
PPR: PBPRB1741
SSE: Ssed_1774
CJA: CJA_3754
DNO: DNO_0679
MPN: MPN114(cpt2)
MPM: MPNA1140
MPJ: MPNE_0131
MPB: C985_0113
MPU: MYPU_7750(MYPU_7750)
CUR: cu1770
NFA: NFA_31870
SFA: Sfla_4630
STRP: F750_2054
KRH: KRH_22440
LMOI: VV02_02115
TCU: Tcur_1929
FAL: FRAAL1805
SEN: SACE_3158
AMD: AMED_6908
AMN: RAM_35440
AMM: AMES_6803
AMZ: B737_6803
AOI: AORI_1812
PDX: Psed_1916
PSEA: WY02_14050
PSEE: FRP1_28500
PSEH: XF36_27750
KAL: KALB_3319
SAQ: Sare_2208
TLI: Tlie_0379
CABY: Cabys_1400
 » show all
Taxonomy
Reference
1  [PMID:14285260]
  Authors
CHASE JF, PEARSON DJ, TUBBS PK.
  Title
THE PREPARATION OF CRYSTALLIN CARNITINE ACETYLTRANSFERASE.
  Journal
Biochim Biophys Acta 96:162-5 (1965)
DOI:10.1016/0005-2787(65)90622-2
Reference
2  [PMID:13275966]
  Authors
FRIEDMAN S, FRAENKEL G.
  Title
Reversible enzymatic acetylation of carnitine.
  Journal
Arch Biochem Biophys 59:491-501 (1955)
DOI:10.1016/0003-9861(55)90515-4
Reference
3  [PMID:6404901]
  Authors
Miyazawa S, Ozasa H, Furuta S, Osumi T, Hashimoto T.
  Title
Purification and properties of carnitine acetyltransferase from rat liver.
  Journal
J Biochem 93:439-51 (1983)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.7
IUBMB Enzyme Nomenclature: 2.3.1.7
ExPASy - ENZYME nomenclature database: 2.3.1.7
BRENDA, the Enzyme Database: 2.3.1.7
CAS: 9029-90-7

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