KEGG   ENZYME: 2.3.1.73Help
Entry
EC 2.3.1.73                 Enzyme                                 

Name
diacylglycerol---sterol O-acyltransferase;
1,2-diacyl-sn-glycerol:sterol acyl transferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
1,2-diacyl-sn-glycerol:sterol O-acyltransferase
Reaction(IUBMB)
a 1,2-diacyl-sn-glycerol + sterol = a 1-acyl-sn-glycerol + sterol ester [RN:R02693]
Reaction(KEGG)
Substrate
1,2-diacyl-sn-glycerol [CPD:C00641];
sterol [CPD:C00370]
Product
1-acyl-sn-glycerol;
sterol ester [CPD:C01958]
Comment
Cholesterol, sitosterol, campesterol and diacylglycerol can act as acceptors. Transfers a number of long-chain fatty acyl groups.
History
EC 2.3.1.73 created 1984
Pathway
ec00100  Steroid biosynthesis
Reference
1
  Authors
Bartlett, K., Keat, M.J. and Mercer, E.I.
  Title
Biosynthesis of sterol esters in Phycomyces blakesleeanus.
  Journal
Phytochemistry 13:1107-1113 (1974)
Reference
2  [PMID:742884]
  Authors
Garcia RE, Mudd JB.
  Title
Metabolism of monoacylglycerol and diacylglycerol by enzyme preparations from spinach leaves.
  Journal
Arch Biochem Biophys 191:487-93 (1978)
DOI:10.1016/0003-9861(78)90387-9
Reference
3
  Authors
Garcia, R.E. and Mudd, J.B.
  Title
1,2-Diacyl-sn-glycerol:sterol acyl transferase from spinach leaves (Spinacia oleracea L.).
  Journal
Methods Enzymol 71:768-772 (1981)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.73
IUBMB Enzyme Nomenclature: 2.3.1.73
ExPASy - ENZYME nomenclature database: 2.3.1.73
BRENDA, the Enzyme Database: 2.3.1.73
CAS: 79586-23-5

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