KEGG   ENZYME: 2.3.1.75Help
Entry
EC 2.3.1.75                 Enzyme                                 

Name
long-chain-alcohol O-fatty-acyltransferase;
wax synthase;
wax-ester synthase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:long-chain-alcohol O-acyltransferase
Reaction(IUBMB)
acyl-CoA + a long-chain alcohol = CoA + a long-chain ester [RN:R01999]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
long-chain alcohol [CPD:C00339]
Product
CoA [CPD:C00010];
long-chain ester [CPD:C02434]
Comment
Transfers saturated or unsaturated acyl residues of chain-length C18 to C20 to long-chain alcohols, forming waxes. The best acceptor is cis-icos-11-en-1-ol.
History
EC 2.3.1.75 created 1984
Pathway
ec00073  Cutin, suberine and wax biosynthesis
Orthology
K00635  diacylglycerol O-acyltransferase / wax synthase
K11155  diacylglycerol O-acyltransferase 1
K11156  diacylglycerol O-acyltransferase 2-like protein 4
K11160  diacylglycerol O-acyltransferase 2
K11171  diacylglycerol O-acyltransferase 2-like protein 3
K15406  wax-ester synthase / diacylglycerol O-acyltransferase
Genes
HSA: 158833(AWAT1) 158835(AWAT2) 84649(DGAT2) 8694(DGAT1)
PTR: 464460(DGAT1) 465684(AWAT1) 466714(DGAT2) 473654(AWAT2)
PPS: 100969745(AWAT2) 100972494(AWAT1) 100987880(DGAT2) 100994391(DGAT1)
GGO: 101124495(AWAT1) 101124779(DGAT2) 101142898(DGAT1) 101153985(AWAT2)
PON: 100442216(DGAT2) 100444717(AWAT2) 100448768(AWAT1) 100453587(DGAT1)
NLE: 100579751(AWAT2) 100580747(AWAT1) 100590733(DGAT1) 100596453(DGAT2)
MCC: 695011(AWAT1) 696451(AWAT2) 696549(DGAT2) 701489(DGAT1)
MCF: 102121566(DGAT1) 102128601(DGAT2) 102128700(AWAT2) 102130614(AWAT1)
CSAB: 103232124(AWAT2) 103232128(AWAT1) 103237618(DGAT1) 103248066(DGAT2)
RRO: 104665097(DGAT2) 104671680(DGAT1) 104678778(AWAT2) 104678782(AWAT1)
RBB: 108526320(AWAT1) 108526323(AWAT2) 108536546(DGAT1) 108545121(DGAT2)
CJC: 100402659(DGAT1) 100406942(AWAT2) 100411885(AWAT1) 100414192(DGAT2)
SBQ: 101035036(AWAT2) 101036517(AWAT1) 101041407(DGAT1) 101049433(DGAT2)
MMU: 13350(Dgat1) 245532(Awat2) 245533(Awat1) 67800(Dgat2)
RNO: 252900(Dgat2) 302425(Awat2) 679520(Awat1) 84497(Dgat1)
CGE: 100755985(Dgat1) 100768365(Awat2) 100769131(Awat1) 100774981(Dgat2)
NGI: 103735255(Dgat1) 103743019(Dgat2) 103743154(Awat2) 103743157(Awat1)
HGL: 101698712(Dgat2) 101701856(Awat2) 101703747(Awat1) 101723650(Dgat1)
CCAN: 109675699 109675846(Awat1) 109680743(Dgat2) 109691174(Dgat1)
OCU: 100340789(AWAT2) 100344355(AWAT1) 100350630(DGAT1) 100354838(DGAT2)
TUP: 102474487(DGAT1) 102484046(AWAT1) 102494423(DGAT2) 102502982(AWAT2)
CFA: 482093(DGAT1) 485185(DGAT2) 491936(AWAT2) 491938(AWAT1)
AML: 100468811(DGAT2) 100475313(AWAT2) 100476302(AWAT1) 100479095(DGAT1)
UMR: 103656696(DGAT1) 103678126(DGAT2) 103682601(AWAT1) 103682604(AWAT2)
ORO: 101366779(DGAT1) 101378818(AWAT1) 101385232(DGAT2) 101386463(AWAT2)
FCA: 101086879(AWAT2) 101087643(AWAT1) 101100329(DGAT2) 101101615(DGAT1)
PTG: 102952153(DGAT2) 102952284(DGAT1) 102971579(AWAT1) 102972443(AWAT2)
AJU: 106976464(DGAT2) 106979135(DGAT1) 106982379(AWAT2) 106982380(AWAT1)
BTA: 282609(DGAT1) 404129(DGAT2) 521298(AWAT2) 529893(AWAT1)
BOM: 102270405(AWAT1) 102275983(AWAT2) 102277779(DGAT1) 102285649(DGAT2)
BIU: 109555083 109569733(DGAT2)
PHD: 102323727(AWAT1) 102331938(AWAT2) 102333981(DGAT1) 102341303 102342059
CHX: 100861225(DGAT1) 102174409(DGAT2) 102175661(AWAT1) 102177144(AWAT2)
OAS: 100126245(DGAT1) 101110535(DGAT2) 101121241(AWAT2) 101122414(AWAT1)
SSC: 100151799(AWAT2) 100294675(DGAT2) 100517507(AWAT1) 397118(DGAT1)
CFR: 102504113(DGAT2) 102514200(AWAT2) 102514959(AWAT1) 102515256(DGAT1)
CDK: 105087971(AWAT1) 105087992(AWAT2) 105097240(DGAT2) 105104999(DGAT1)
BACU: 103001320(DGAT1) 103009724(AWAT2) 103018277(DGAT2)
LVE: 103073062(DGAT1) 103074572(AWAT2) 103075069(DGAT2)
OOR: 101275488(DGAT1) 101282586(AWAT2) 101283358(DGAT2)
ECB: 100056316(AWAT1) 100064387(DGAT2) 100066473(AWAT2) 100147359(DGAT1)
EPZ: 103540220(DGAT1) 103540669(AWAT1) 103541350(AWAT2) 103545802 103548227(DGAT2)
EAI: 106827656(AWAT2) 106827657(AWAT1) 106840399(DGAT2) 106841896(DGAT1)
MYB: 102242085(AWAT2) 102249216 102261774(DGAT2) 102263477(AWAT1) 102263903(DGAT1)
MYD: 102751521(AWAT1) 102753473(DGAT2) 102760049(AWAT2) 102769363(DGAT1)
HAI: 109375066(DGAT1) 109385592(AWAT1) 109386362(DGAT2)
RSS: 109435253(DGAT1) 109444790(DGAT2) 109455952(AWAT2) 109455982(AWAT1)
PALE: 102885568(AWAT1) 102889573(DGAT1) 102895732(AWAT2) 102898739(DGAT2)
LAV: 100655991 100657191(DGAT2) 100666264(AWAT1) 100669668(AWAT2) 104845744
MDO: 100011089(DGAT2) 100014237(AWAT1) 100014456(AWAT2) 100018271(DGAT1)
SHR: 100914285(DGAT2) 100924635(DGAT1) 100931966(AWAT2) 100933522(AWAT1)
OAA: 100088895(DGAT2) 103166832(DGAT1)
GGA: 421309(DGAT2) 428693(AWAT1)
MGP: 100540643 100545351(DGAT2)
CJO: 107308594(DGAT2) 107312638
APLA: 101792641 101801215(DGAT2)
ACYG: 106042403(DGAT2) 106042952
TGU: 100220095(DGAT2)
GFR: 102035873(DGAT2) 102037230
FAB: 101810713(DGAT2) 101820931
PHI: 102100921 102107779(DGAT2)
PMAJ: 107204039 107211569(DGAT2)
CCW: 104686963(DGAT2) 104691343
FPG: 101917877 101924658(DGAT2) 106112364(DGAT1)
FCH: 102055207(DGAT2) 102057990 106631435(DGAT1)
CLV: 102085339 102087439(DGAT2)
EGZ: 104124768(DGAT2) 104135988
AMJ: 102557932(DGAT2) 102576196(DGAT1) 102576534(AWAT2)
PSS: 102448420(DGAT1) 102449336 102453357(DGAT2)
CPIC: 101930999(DGAT2) 101950557 101950960(DGAT1) 101951746
ACS: 100551857(dgat1) 100552736(dgat2) 100555636
PVT: 110074308 110084814(DGAT1) 110087798(DGAT2)
PBI: 103052621(DGAT2) 103065772(DGAT1)
GJA: 107110553 107110672(DGAT1) 107112091(DGAT2)
XLA: 100126612(awat1.L) 100127341 100381012(dgat1.L) 108698316(dgat2l6.L) 108710042(dgat2.S) 108710383(mogat3.L) 398800(dgat2.L)
XTR: 100127622(awat1) 100127752(dgat2l6) 100491581(mogat3) 101730812(dgat1) 395003(dgat2)
DRE: 325875(dgat1a) 565316(dgat2)
PRET: 103472475(dgat1) 103475773 103476122(dgat2) 103478641
LCM: 102349959(DGAT1) 102351093(DGAT2) 102358735 102359647(MOGAT3) 102360601
CIN: 100177672
SPU: 575003
APLC: 110982992
SKO: 100376218
DME: Dmel_CG31991(mdy)
DSI: Dsimw501_GD24087(Dsim_GD24087)
MDE: 101894841
AAG: 5569069
AME: 552377
BIM: 100744121
BTER: 100646196
SOC: 105194711
AEC: 105151363
ACEP: 105618616
PBAR: 105422883
HST: 105182283
CFO: 105253928
LHU: 105676355
PGC: 109852637
NVI: 100116518
TCA: 664028
DPA: 109533688
NVL: 108568180
BMOR: 101742497
PMAC: 106710683
PRAP: 110991401
FCD: 110852290
TUT: 107362581
CEL: CELE_H19N07.4(mboa-2)
CBR: CBG23107
BMY: Bm1_52020
TSP: Tsp_02502
CRG: 105331361
MYI: 110442476
OBI: 106869194
LAK: 106165236
SHX: MS3_08893
EGL: EGR_02006
EPA: 110238682
ADF: 107351603
HMG: 101238034
ATH: AT2G19450(TAG1) AT5G37300(WSD1)
CIT: 102619099
TCC: 18588364
GRA: 105793287
GHI: 107932255
DZI: 111286703
EGR: 104438076
GMX: 547982(DGAT) 548005(DGAT1A) 732606(DGAT1b)
LJA: Lj4g3v2172770.1(Lj4g3v2172770.1) Lj4g3v2172770.2(Lj4g3v2172770.2) Lj6g3v1226310.1(Lj6g3v1226310.1)
FVE: 101304125
PPER: 18769247
PMUM: 103340712
PAVI: 110749273
MDM: 103400825
ZJU: 107424129
CSV: 101213517
CMO: 103498593
MCHA: 111021903
CMAX: 111493820
CMOS: 111450373
RCU: 8272569
JCU: 105637897(DGAT1)
VVI: 100266364
SIND: 105173637(DGAT1)
LSV: 111892564
BVG: 104909051
SOE: 110797728
NNU: 104586668
DOSA: Os05t0196800-00(Os05g0196800) Os06t0563900-01(Os06g0563900)
ATS: 109752785(LOC109752785) 109765064(LOC109765064)
ZMA: 100383910 103629820(DGAT1-2)
AOF: 109828648
ATR: 18443650
MNG: MNEG_1183
APRO: F751_6502
SLB: AWJ20_4739(ARE2)
NCR: NCU00035
NTE: NEUTE1DRAFT129602(NEUTE1DRAFT_129602)
MGR: MGG_05326
SSCK: SPSK_02335
MAW: MAC_07178
MAJ: MAA_07086
CMT: CCM_05029
MBE: MBM_00351
ANI: AN6159.2
ANG: ANI_1_1688104(An12g03600)
ABE: ARB_04951
TVE: TRV_06710
PTE: PTT_18543
DDI: DDB_G0271342(dgat1)
PYO: PY17X_1219400(PY01256)
PCB: PCHAS_121690(PC301445.00.0)
TAN: TA19620
TPV: TP01_0247
BBO: BBOV_IV004970(23.m06462)
CPV: cgd2_1090
PSHI: SAMEA2665130_1588(tgs2)
PCQ: PcP3B5_33150(wax-dgaT)
PAR: Psyc_0223
PALI: A3K91_0285
PSYA: AOT82_1515
ACB: A1S_2776
ABM: ABSDF0686(wax-dgaT)
ABY: ABAYE0708(wax-dgaT)
ABN: AB57_3277
ABX: ABK1_3078
ABH: M3Q_3256
ABAD: ABD1_27220(wax-dgaT)
ABAZ: P795_3265
ABAU: IX87_10725
ABAA: IX88_17050
ACI: ACIAD0832(wax-dgaT)
MCT: MCR_1402
MCS: DR90_526(wax-dgaT)
MCAT: MC25239_01357(wax-dgaT)
MHC: MARHY0163(wax-dgaT) MARHY0721 MARHY3006
AMAL: I607_12125
AMAE: I876_12500
AMAO: I634_12355
AMAD: I636_12495
AMAI: I635_12860
AMAG: I533_12105
AMAC: MASE_11900
AAUS: EP12_12730
ASP: AOR13_989
GNI: GNIT_1288
HCH: HCH_05018
ABO: ABO_2742(atfA1)
ADI: B5T_04434(atfA1)
APAC: S7S_18395
AXE: P40_21630
RGE: RGE_07320
BRS: S23_51360
BRAD: BF49_1814
SGI: SGRAN_3397(atfA)
SSAN: NX02_21015
BLAS: BSY18_1483
MLE: ML1244
MLB: MLBr01244
MTHN: 4412656_00222(wax-dgaT) 4412656_00271(tgs1) 4412656_00813(tgs2_1) 4412656_01213(tgs3) 4412656_01808(tgs2_2) 4412656_02948(tgs4_1) 4412656_03292(tgs4_2) 4412656_03900(tgs2_3)
MTER: 4434518_00171(wax-dgaT_1) 4434518_01314(wax-dgaT_2) 4434518_02445(tgs1_1) 4434518_02908(tgs3) 4434518_02970(tgs1_2) 4434518_03621(wax-dgaT_3) 4434518_03975(tgs2)
RFA: A3L23_00029(tgs3) A3L23_00541(tgs2)
RHS: A3Q41_02812(tgs2) A3Q41_03384(tgs3)
SCO: SCO0123(SCJ21.04c) SCO0958(SCM11.13c) SCO1280(2SCG18.27c)
SMA: SAVERM_7256(tgs)
SGR: SGR_725
SGB: WQO_31540
SFA: Sfla_0439
SBH: SBI_10013
SHY: SHJG_7843
STRP: F750_6559
SFI: SFUL_6709
SLD: T261_0684
STRM: M444_06555
SPRI: SPRI_6803
SRW: TUE45_00141(tgs1)
SLE: sle_07290(sle_07290) sle_59870(sle_59870)
SMAL: SMALA_6742
SFK: KY5_7376
KSK: KSE_72050
CFI: Celf_3117
TCU: Tcur_0504
FAL: FRAAL4187
MMAR: MODMU_4673
SEN: SACE_6439
PDX: Psed_5172
AMI: Amir_6300
KAL: KALB_7880
ACTI: UA75_27080
ACAD: UA74_26495
AHG: AHOG_24410(tgs3)
CWO: Cwoe_1834
 » show all
Taxonomy
Reference
1
  Authors
Wu, X.-Y., Moreau, R.A. and Stumpf, P.K.
  Title
Studies of biosynthesis of waxes by developing jojoba seed. 3. Biosynthesis of wax esters from acyl-CoA and long-chain alcohols.
  Journal
Lipids 16:897-902 (1981)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.75
IUBMB Enzyme Nomenclature: 2.3.1.75
ExPASy - ENZYME nomenclature database: 2.3.1.75
BRENDA, the Enzyme Database: 2.3.1.75
CAS: 64060-40-8

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