KEGG   ENZYME: 2.3.1.76Help
Entry
EC 2.3.1.76                 Enzyme                                 

Name
retinol O-fatty-acyltransferase;
retinol acyltransferase;
retinol fatty-acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:retinol O-acyltransferase
Reaction(IUBMB)
acyl-CoA + retinol = CoA + retinyl ester [RN:R02366]
Reaction(KEGG)
R02366 > R02367;
(other) R08381
Show
Substrate
acyl-CoA [CPD:C00040];
retinol [CPD:C00473]
Product
CoA [CPD:C00010];
retinyl ester [CPD:C02075]
Comment
Acts on palmitoyl-CoA and other long-chain fatty-acyl derivatives of CoA.
History
EC 2.3.1.76 created 1984
Pathway
ec00830  Retinol metabolism
Orthology
K11155  diacylglycerol O-acyltransferase 1
K11156  diacylglycerol O-acyltransferase 2-like protein 4
Genes
HSA: 158835(AWAT2) 8694(DGAT1)
PTR: 464460(DGAT1) 473654(AWAT2)
PPS: 100969745(AWAT2) 100994391(DGAT1)
GGO: 101142898(DGAT1) 101153985(AWAT2)
PON: 100444717(AWAT2) 100453587(DGAT1)
NLE: 100579751(AWAT2) 100590733(DGAT1)
MCC: 696451(AWAT2) 701489(DGAT1)
MCF: 102121566(DGAT1) 102128700(AWAT2)
CSAB: 103232124(AWAT2) 103237618(DGAT1)
RRO: 104671680(DGAT1) 104678778(AWAT2)
RBB: 108526323(AWAT2) 108536546(DGAT1)
CJC: 100402659(DGAT1) 100406942(AWAT2)
SBQ: 101035036(AWAT2) 101041407(DGAT1)
MMU: 13350(Dgat1) 245532(Awat2)
RNO: 302425(Awat2) 84497(Dgat1)
CGE: 100755985(Dgat1) 100768365(Awat2)
NGI: 103735255(Dgat1) 103743154(Awat2)
HGL: 101701856(Awat2) 101723650(Dgat1)
CCAN: 109675699 109691174(Dgat1)
OCU: 100340789(AWAT2) 100350630(DGAT1)
TUP: 102474487(DGAT1) 102502982(AWAT2)
CFA: 482093(DGAT1) 491936(AWAT2)
AML: 100475313(AWAT2) 100479095(DGAT1)
UMR: 103656696(DGAT1) 103682604(AWAT2)
ORO: 101366779(DGAT1) 101386463(AWAT2)
FCA: 101086879(AWAT2) 101101615(DGAT1)
PTG: 102952284(DGAT1) 102972443(AWAT2)
AJU: 106979135(DGAT1) 106982379(AWAT2)
BTA: 282609(DGAT1) 521298(AWAT2)
BOM: 102275983(AWAT2) 102277779(DGAT1)
PHD: 102331938(AWAT2) 102333981(DGAT1)
CHX: 100861225(DGAT1) 102177144(AWAT2)
OAS: 100126245(DGAT1) 101121241(AWAT2)
SSC: 100151799(AWAT2) 397118(DGAT1)
CFR: 102514200(AWAT2) 102515256(DGAT1)
CDK: 105087992(AWAT2) 105104999(DGAT1)
BACU: 103001320(DGAT1) 103009724(AWAT2)
LVE: 103073062(DGAT1) 103074572(AWAT2)
OOR: 101275488(DGAT1) 101282586(AWAT2)
ECB: 100066473(AWAT2) 100147359(DGAT1)
EPZ: 103540220(DGAT1) 103541350(AWAT2) 103545802
EAI: 106827656(AWAT2) 106841896(DGAT1)
MYB: 102242085(AWAT2) 102263903(DGAT1)
MYD: 102760049(AWAT2) 102769363(DGAT1)
HAI: 109375066(DGAT1)
RSS: 109435253(DGAT1) 109455952(AWAT2)
PALE: 102889573(DGAT1) 102895732(AWAT2)
MDO: 100014456(AWAT2) 100018271(DGAT1)
SHR: 100924635(DGAT1) 100931966(AWAT2)
OAA: 103166832(DGAT1)
FPG: 106112364(DGAT1)
FCH: 106631435(DGAT1)
AAM: 106485793 106487807(DGAT1)
ASN: 102375256(DGAT1) 112549700
AMJ: 102576196(DGAT1)
PSS: 102448420(DGAT1)
CMY: 102930647 102932469(DGAT1)
CPIC: 101950960(DGAT1) 101951746
ACS: 100551857(dgat1)
PVT: 110084814(DGAT1)
PBI: 103065772(DGAT1)
GJA: 107110672(DGAT1)
XLA: 100381012(dgat1.L)
XTR: 101730812(dgat1)
NPR: 108799410(DGAT1)
DRE: 325875(dgat1a)
IPU: 108257065(dgat1) 108267870
TRU: 101072465 101079602(dgat1)
XMA: 102220430 102225690(dgat1)
PRET: 103472475(dgat1) 103478641
ELS: 105018848 105022840(dgat1)
LCM: 102349959(DGAT1) 102358735
CMK: 103183634(dgat1) 103185953
CIN: 100177672
SPU: 575003
APLC: 110982992
SKO: 100376218
DME: Dmel_CG31991(mdy)
DSI: Dsimw501_GD24087(Dsim_GD24087)
MDE: 101894841
AAG: 5569069
AME: 552377
BIM: 100744121
BTER: 100646196
SOC: 105194711
AEC: 105151363
ACEP: 105618616
PBAR: 105422883
HST: 105182283
DQU: 106747317
CFO: 105253928
LHU: 105676355
PGC: 109852637
PCF: 106788280
NVI: 100116518
MDL: 103568794
TCA: 664028
DPA: 109533688
NVL: 108568180
BMOR: 101742497
PMAC: 106710683
PRAP: 110991401
HAW: 110371905
CLEC: 106668819
FCD: 110852290
TUT: 107362581
CEL: CELE_H19N07.4(mboa-2)
CBR: CBG23107
BMY: Bm1_52020
TSP: Tsp_02502
CRG: 105331361
MYI: 110442476
OBI: 106869194
LAK: 106165236
SHX: MS3_08893
EGL: EGR_02006
EPA: 110238682
ADF: 107351603
HMG: 101238034
ATH: AT2G19450(TAG1)
CRB: 17891447
CIT: 102619099
TCC: 18588364
GRA: 105793287
GHI: 107932255
DZI: 111286703
EGR: 104438076
GMX: 547982(DGAT) 548005(DGAT1A) 732606(DGAT1b)
LJA: Lj4g3v2172770.1(Lj4g3v2172770.1) Lj4g3v2172770.2(Lj4g3v2172770.2) Lj6g3v1226310.1(Lj6g3v1226310.1)
FVE: 101304125
PPER: 18769247
PMUM: 103340712
PAVI: 110749273
MDM: 103400825
ZJU: 107424129
CSV: 101213517
CMO: 103498593
MCHA: 111021903
CMAX: 111493820
CMOS: 111450373
RCU: 8272569
JCU: 105637897(DGAT1)
VVI: 100266364
SIND: 105173637(DGAT1)
LSV: 111892564
BVG: 104909051
SOE: 110797728
NNU: 104586668
DOSA: Os05t0196800-00(Os05g0196800) Os06t0563900-01(Os06g0563900)
ATS: 109752785(LOC109752785) 109765064(LOC109765064)
ZMA: 100383910 103629820(DGAT1-2)
PEQ: 110022299
AOF: 109828648
ATR: 18443650
MNG: MNEG_1183
APRO: F751_6502
SLB: AWJ20_4739(ARE2)
NCR: NCU00035
NTE: NEUTE1DRAFT129602(NEUTE1DRAFT_129602)
MGR: MGG_05326
SSCK: SPSK_02335
MAW: MAC_07178
MAJ: MAA_07086
CMT: CCM_05029
MBE: MBM_00351
ANI: AN6159.2
ANG: ANI_1_1688104(An12g03600)
ABE: ARB_04951
TVE: TRV_06710
PTE: PTT_18543
DDI: DDB_G0271342(dgat1)
PYO: PY17X_1219400(PY01256)
PCB: PCHAS_121690(PC301445.00.0)
TAN: TA19620
TPV: TP01_0247
BBO: BBOV_IV004970(23.m06462)
CPV: cgd2_1090
 » show all
Taxonomy
Reference
1  [PMID:6826734]
  Authors
Helgerud P, Petersen LB, Norum KR.
  Title
Retinol esterification by microsomes from the mucosa of human small intestine. Evidence for acyl-Coenzyme A retinol acyltransferase activity.
  Journal
J Clin Invest 71:747-53 (1983)
Reference
2  [PMID:7061433]
  Authors
Ross AC.
  Title
Retinol esterification by rat liver microsomes. Evidence for a fatty acyl coenzyme A: retinol acyltransferase.
  Journal
J Biol Chem 257:2453-9 (1982)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.76
IUBMB Enzyme Nomenclature: 2.3.1.76
ExPASy - ENZYME nomenclature database: 2.3.1.76
BRENDA, the Enzyme Database: 2.3.1.76
CAS: 81295-48-9

DBGET integrated database retrieval system