KEGG   ENZYME: 2.3.1.76Help
Entry
EC 2.3.1.76                 Enzyme                                 

Name
retinol O-fatty-acyltransferase;
retinol acyltransferase;
retinol fatty-acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:retinol O-acyltransferase
Reaction(IUBMB)
acyl-CoA + retinol = CoA + retinyl ester [RN:R02366]
Reaction(KEGG)
R02366 > R02367;
(other) R08381
Show
Substrate
acyl-CoA [CPD:C00040];
retinol [CPD:C00473]
Product
CoA [CPD:C00010];
retinyl ester [CPD:C02075]
Comment
Acts on palmitoyl-CoA and other long-chain fatty-acyl derivatives of CoA.
History
EC 2.3.1.76 created 1984
Pathway
ec00830  Retinol metabolism
Orthology
K11155  diacylglycerol O-acyltransferase 1
K11156  diacylglycerol O-acyltransferase 2-like protein 4
Genes
HSA: 158835(AWAT2) 8694(DGAT1)
PTR: 464460(DGAT1) 473654(AWAT2)
PPS: 100969745(AWAT2) 100994391(DGAT1)
GGO: 101142898(DGAT1) 101153985(AWAT2)
PON: 100444717(AWAT2) 100453587(DGAT1)
NLE: 100579751(AWAT2) 100590733(DGAT1)
MCC: 696451(AWAT2) 701489(DGAT1)
MCF: 102121566(DGAT1) 102128700(AWAT2)
CSAB: 103232124(AWAT2) 103237618(DGAT1)
RRO: 104671680(DGAT1) 104678778(AWAT2)
RBB: 108526323(AWAT2) 108536546(DGAT1)
CJC: 100402659(DGAT1) 100406942(AWAT2)
SBQ: 101035036(AWAT2) 101041407(DGAT1)
MMU: 13350(Dgat1) 245532(Awat2)
RNO: 302425(Awat2) 84497(Dgat1)
CGE: 100755985(Dgat1) 100768365(Awat2)
NGI: 103735255(Dgat1) 103743154(Awat2)
HGL: 101701856(Awat2) 101723650(Dgat1)
CCAN: 109675699 109691174(Dgat1)
OCU: 100340789(AWAT2) 100350630(DGAT1)
TUP: 102474487(DGAT1) 102502982(AWAT2)
CFA: 482093(DGAT1) 491936(AWAT2)
AML: 100475313(AWAT2) 100479095(DGAT1)
UMR: 103656696(DGAT1) 103682604(AWAT2)
ORO: 101366779(DGAT1) 101386463(AWAT2)
FCA: 101086879(AWAT2) 101101615(DGAT1)
PTG: 102952284(DGAT1) 102972443(AWAT2)
AJU: 106979135(DGAT1) 106982379(AWAT2)
BTA: 282609(DGAT1) 521298(AWAT2)
BOM: 102275983(AWAT2) 102277779(DGAT1)
PHD: 102331938(AWAT2) 102333981(DGAT1)
CHX: 100861225(DGAT1) 102177144(AWAT2)
OAS: 100126245(DGAT1) 101121241(AWAT2)
SSC: 100151799(AWAT2) 397118(DGAT1)
CFR: 102514200(AWAT2) 102515256(DGAT1)
CDK: 105087992(AWAT2) 105104999(DGAT1)
BACU: 103001320(DGAT1) 103009724(AWAT2)
LVE: 103073062(DGAT1) 103074572(AWAT2)
OOR: 101275488(DGAT1) 101282586(AWAT2)
ECB: 100066473(AWAT2) 100147359(DGAT1)
EPZ: 103540220(DGAT1) 103541350(AWAT2) 103545802
EAI: 106827656(AWAT2) 106841896(DGAT1)
MYB: 102242085(AWAT2) 102263903(DGAT1)
MYD: 102760049(AWAT2) 102769363(DGAT1)
HAI: 109375066(DGAT1)
RSS: 109435253(DGAT1) 109455952(AWAT2)
PALE: 102889573(DGAT1) 102895732(AWAT2)
LAV: 100655991 100669668(AWAT2) 104845744
TMU: 101350605 105756481
MDO: 100014456(AWAT2) 100018271(DGAT1)
SHR: 100924635(DGAT1) 100931966(AWAT2)
OAA: 103166832(DGAT1)
FPG: 106112364(DGAT1)
FCH: 106631435(DGAT1)
AAM: 106485793 106487807(DGAT1)
ASN: 102375256(DGAT1) 112549700
AMJ: 102576196(DGAT1)
PSS: 102448420(DGAT1)
CMY: 102930647 102932469(DGAT1)
CPIC: 101950960(DGAT1) 101951746
ACS: 100551857(dgat1)
PVT: 110084814(DGAT1)
PBI: 103065772(DGAT1)
GJA: 107110672(DGAT1)
XLA: 100381012(dgat1.L)
XTR: 101730812(dgat1)
NPR: 108799410(DGAT1)
DRE: 325875(dgat1a)
SRX: 107706563 107724797 107741726 107751676
SANH: 107655125 107671724 107694771 107704850
SGH: 107552801 107557468 107566613 107587805
CCAR: 109081342 109081349 109081683 109092539 109111091
IPU: 108257065(dgat1) 108267870
AMEX: 103031398 103039575
TRU: 101072465 101079602(dgat1)
TNG: GSTEN00032560G001 GSTEN00034052G001
LCO: 104919541(dgat1) 104933582 104940359
NCC: 104952230 104952233 104959283(dgat1)
MZE: 101469920 101473178 101487504 112435568
OLA: 101155899 101166984
XMA: 102220430 102225690(dgat1)
PRET: 103472475(dgat1) 103478641
NFU: 107389273 107394608 107395184
KMR: 108241110 108242037
CSEM: 103388561 103394287
LCF: 108879464 108889635 108901956
SDU: 111223509 111236802 111238841
HCQ: 109512011 109518042
BPEC: 110160303 110161130 110171646
MALB: 109958740 109967303
SASA: 100136500(dgat1) 106560908 106570407 106588986 106605973 106606064 106606100
OTW: 112218465 112229529 112243899 112264326
ELS: 105018848 105022840(dgat1)
SFM: 108922051(dgat1) 108926542 108940649
LCM: 102349959(DGAT1) 102358735
CMK: 103183634(dgat1) 103185953
BFO: BRAFLDRAFT_280106
CIN: 100177672
SPU: 575003
APLC: 110982992
SKO: 100376218
DME: Dmel_CG31991(mdy)
DPO: Dpse_GA16599
DAN: Dana_GF15369
DER: 6547631
DPE: 6589755
DSE: Dsec_GM17212
DSI: Dsimw501_GD24087(Dsim_GD24087)
DWI: 6643530
DYA: Dyak_GE12771
DGR: Dgri_GH13104
DMO: Dmoj_GI14192
DVI: Dvir_GJ17509
MDE: 101894841
AGA: AgaP_AGAP007843
AAG: 5569069
CQU: CpipJ_CPIJ005914
AME: 552377
BIM: 100744121
BTER: 100646196
SOC: 105194711
AEC: 105151363
ACEP: 105618616
PBAR: 105422883
HST: 105182283
DQU: 106747317
CFO: 105253928
LHU: 105676355
PGC: 109852637
PCF: 106788280
NVI: 100116518
MDL: 103568794
TCA: 664028
DPA: 109533688
NVL: 108568180
BMOR: 101742497
DPL: KGM_215813
PMAC: 106710683
PRAP: 110991401
HAW: 110371905
CLEC: 106668819
PHU: Phum_PHUM464830
ZNE: 110828835 110841191
FCD: 110852290
DPX: DAPPUDRAFT_300124
ISC: IscW_ISCW001074 IscW_ISCW004340
TUT: 107362581
CEL: CELE_H19N07.4(mboa-2)
CBR: CBG23107
NAI: NECAME_15885
BMY: Bm1_52020
LOA: LOAG_07245
TSP: Tsp_02502
HRO: HELRODRAFT_193513
LGI: LOTGIDRAFT_231331
CRG: 105331361
MYI: 110442476
OBI: 106869194
LAK: 106165236
SMM: Smp_127280
SHX: MS3_08893
OVI: T265_00228
EGL: EGR_02006
NVE: NEMVE_v1g239390
EPA: 110238682
ADF: 107351603
HMG: 101238034
TAD: TRIADDRAFT_35841
AQU: 100636603 100637352 100640646 109592520
ATH: AT2G19450(TAG1)
ALY: ARALYDRAFT_480528
CRB: 17891447
CSAT: 104701387 104748933 104767141
EUS: EUTSA_v10022645mg
BRP: 103828297 103837958
BNA: 106352950 106375527 106382435 106402120 106406949 106436339
BOE: 106301685 106313337
THJ: 104814629 104820018
CPAP: 110817535 110817543
CIT: 102619099
CIC: CICLE_v100080481m
TCC: 18588364
GRA: 105793287
GHI: 107932255
DZI: 111286703
EGR: 104438076
GMX: 547982(DGAT) 548005(DGAT1A) 732606(DGAT1b)
PVU: PHAVU_003G134900g PHAVU_009G230700g
VRA: 106759755 106769144
VAR: 108331823 108338536
CCAJ: 109804420 109807689
MTR: MTR_2g039940 MTR_4g125980
CAM: 101497785 101507886
LJA: Lj4g3v2172770.1(Lj4g3v2172770.1) Lj4g3v2172770.2(Lj4g3v2172770.2) Lj6g3v1226310.1(Lj6g3v1226310.1)
ADU: 107478843 107496826
AIP: 107630508 107643251
LANG: 109326199 109328042 109347548
FVE: 101304125
PPER: 18769247
PMUM: 103340712
PAVI: 110749273
MDM: 103400825
PXB: 103940921 103951884
ZJU: 107424129
CSV: 101213517
CMO: 103498593
MCHA: 111021903
CMAX: 111493820
CMOS: 111450373
CPEP: 111785055 111805863
RCU: 8272569
JCU: 105637897(DGAT1)
HBR: 110633612 110642432
POP: 18107695 7484659
JRE: 109009388 109009971
VVI: 100266364
SLY: 101245821 101264840
SPEN: 107005263 107026503
SOT: 102592250 102593515
CANN: 107840924 107877877
NTA: 107775049 107784357 107789692 107821867(DAGAT) 107830919
NSY: 104222136 104228678
NTO: 104094249 104100752
INI: 109148038 109169022
SIND: 105173637(DGAT1)
OEU: 111366337 111383725 111399475
HAN: 110886978 110893727 110928453
LSV: 111892564
CCAV: 112501304 112516398
DCR: 108197160 108210867
BVG: 104909051
SOE: 110797728
NNU: 104586668
OSA: 4338045 4341317
DOSA: Os05t0196800-00(Os05g0196800) Os06t0563900-01(Os06g0563900)
OBR: 102716701 102716784
BDI: 100827885 100832396
ATS: 109752785(LOC109752785) 109765064(LOC109765064)
SBI: 8055715 8076727
ZMA: 100383910 103629820(DGAT1-2)
SITA: 101759157 101778658
PDA: 103709557 103719431
EGU: 105040465 105047643 105047997
MUS: 103968850 103999268
DCT: 110097309 110099629 110107905
PEQ: 110022299
AOF: 109828648
ATR: 18443650
SMO: SELMODRAFT_138381(TAG1-2) SELMODRAFT_404425 SELMODRAFT_81638
PPP: 112287010 112292007
VCN: VOLCADRAFT_69078
MNG: MNEG_1183
CSL: COCSUDRAFT_54084
CVR: CHLNCDRAFT_28812
APRO: F751_6502
CME: CYME_CMQ199C
GSL: Gasu_29900
CCP: CHC_T00007755001 CHC_T00009240001 CHC_T00010127001
YLI: YALI0D07986g
SLB: AWJ20_4739(ARE2)
NCR: NCU00035
NTE: NEUTE1DRAFT129602(NEUTE1DRAFT_129602)
SMP: SMAC_00123
PAN: PODANSg5375
TTT: THITE_2119816
MTM: MYCTH_2303878
CTHR: CTHT_0069450
MGR: MGG_05326
TMN: UCRPA7_366
SSCK: SPSK_02335
FGR: FGSG_06688
FPU: FPSE_01558
FVR: FVEG_05426
FOX: FOXG_02252
NHE: NECHADRAFT_100228
TRE: TRIREDRAFT_61705
MAW: MAC_07178
MAJ: MAA_07086
CMT: CCM_05029
PLJ: VFPFJ_05773
VAL: VDBG_08786
VDA: VDAG_06444
CFJ: CFIO01_03366
ELA: UCREL1_6688
PFY: PFICI_11496
SSL: SS1G_13567
BFU: BCIN_16g01220
MBE: MBM_00351
PSCO: LY89DRAFT_631653
GLZ: GLAREA_07814
ANI: AN6159.2
AFM: AFUA_2G08380
AOR: AO090011000863
ANG: ANI_1_1688104(An12g03600)
AFV: AFLA_046610
ACT: ACLA_080210
NFI: NFIA_084010
PCS: Pc13g04400
PDP: PDIP_85010
CIM: CIMG_00860
CPW: CPC735_054550
PBL: PAAG_07527
PBN: PADG_05222
URE: UREG_00818
ABE: ARB_04951
TVE: TRV_06710
AJE: HCAG_07348
PNO: SNOG_13711
PTE: PTT_18543
BZE: COCCADRAFT_101346
BSC: COCSADRAFT_91729
BOR: COCMIDRAFT_9045
AALT: CC77DRAFT_1015346
ZTR: MYCGRDRAFT_108832
PFJ: MYCFIDRAFT_153247
BCOM: BAUCODRAFT_120378
NPA: UCRNP2_5448
TML: GSTUM_00010199001
ECU: ECU10_0300
EIN: Eint_100250
EHE: EHEL_100300
ERO: EROM_100180
NCE: NCER_100059
MBR: MONBRDRAFT_20830
SRE: PTSG_02810
DDI: DDB_G0271342(dgat1)
DPP: DICPUDRAFT_154444
DFA: DFA_06763 DFA_11930
ACAN: ACA1_151370
PFA: PF3D7_0322300
PFD: PFDG_00612
PFH: PFHG_03156
PYO: PY17X_1219400(PY01256)
PCB: PCHAS_121690(PC301445.00.0)
PBE: PBANKA_121620
PKN: PKH_081830
PVX: PVX_095120
PCY: PCYB_082750
TAN: TA19620
TPV: TP01_0247
TOT: TOT_010000236
BEQ: BEWA_032080
BBO: BBOV_IV004970(23.m06462)
BMIC: BMR1_02g00690
CPV: cgd2_1090
CHO: Chro.20121
TGO: TGME49_232730
TET: TTHERM_00046260
PTM: GSPATT00008374001 GSPATT00013044001 GSPATT00021071001 GSPATT00022974001
PTI: PHATRDRAFT_9794
FCY: FRACYDRAFT_276226
TPS: THAPSDRAFT_261279(DGT)
AAF: AURANDRAFT_3067
EHX: EMIHUDRAFT_64505
GTT: GUITHDRAFT_113937
NGR: NAEGRDRAFT_57973 NAEGRDRAFT_80131 NAEGRDRAFT_80541
 » show all
Taxonomy
Reference
1  [PMID:6826734]
  Authors
Helgerud P, Petersen LB, Norum KR.
  Title
Retinol esterification by microsomes from the mucosa of human small intestine. Evidence for acyl-Coenzyme A retinol acyltransferase activity.
  Journal
J Clin Invest 71:747-53 (1983)
Reference
2  [PMID:7061433]
  Authors
Ross AC.
  Title
Retinol esterification by rat liver microsomes. Evidence for a fatty acyl coenzyme A: retinol acyltransferase.
  Journal
J Biol Chem 257:2453-9 (1982)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.76
IUBMB Enzyme Nomenclature: 2.3.1.76
ExPASy - ENZYME nomenclature database: 2.3.1.76
BRENDA, the Enzyme Database: 2.3.1.76
CAS: 81295-48-9

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Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (5)   
   KEGG REACTION (3)   
   KEGG RCLASS (2)   
Gene (3429)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (542)   
   KEGG MGENES (328)   
   RefGene (2557)   
Protein sequence (41)   
   UniProt (16)   
   SWISS-PROT (11)   
   RefSeq(pep) (14)   
DNA sequence (24)   
   RefSeq(nuc) (19)   
   GenBank (5)   
All databases (3510)   

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