KEGG ENZYME: 2.4.1.10

ENZYME: 2.4.1.10

Entry

EC 2.4.1.10                 Enzyme

Name

levansucrase;
sucrose 6-fructosyltransferase;
beta-2,6-fructosyltransferase;
beta-2,6-fructan:D-glucose 1-fructosyltransferase;
sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase;
sucrose:(2->6)-beta-D-fructan 6-beta-D-fructosyltransferase

Class

Transferases;
Glycosyltransferases;
Hexosyltransferases

Sysname

sucrose:[6)-beta-D-fructofuranosyl-(2->]n alpha-D-glucopyranoside 6-beta-D-fructosyltransferase

Reaction(IUBMB)

sucrose + [6)-beta-D-fructofuranosyl-(2->]n alpha-D-glucopyranoside = D-glucose + [6)-beta-D-fructofuranosyl-(2->]n+1 alpha-D-glucopyranoside [RN:R05140 R06079]

Reaction(KEGG)

R05140 R06079(G) > R06079(G)

Substrate

sucrose [CPD:C00089];
[6)-beta-D-fructofuranosyl-(2->]n alpha-D-glucopyranoside

Product

D-glucose [CPD:C00031];
[6)-beta-D-fructofuranosyl-(2->]n+1 alpha-D-glucopyranoside

Comment

Some other sugars can act as D-fructosyl acceptors.

History

EC 2.4.1.10 created 1961, modified 2011

Pathway

ec00500

Starch and sucrose metabolism

ec01100

Metabolic pathways

Orthology

K00692

levansucrase

Genes

SRL:	SOD_c35120(lsc)

SRY:	M621_19025

SOF:	NCTC11214_03700(sacC)

RAH:	Rahaq_1623

RACE:

JHW33_02345(sacB)

RAQ:	Rahaq2_5035

RAA:

Q7S_07855

ROX:	BV494_03430

RIU:	I2123_07885

GQU:	AWC35_15285

SERA:

Ser39006_005400

SERQ:

CWC46_05395

PROD:

PCO85_20145

PAQU:

DMB82_0000655

BGJ:	AWC36_15980

BRB:	EH207_01855

BNG:	EH206_19850

BIZ:	HC231_21005

LBQ:	CKQ53_01625

LPOP:

I6N93_03210

EAM:	EAMY_3695(lscC)

EAY:	EAM_3468(lsc)

ETA:	ETA_34670(lsc)

PAGG:

AL522_00755

TCI:	A7K98_02365 A7K98_02375

TPTY:

NCTC11468_00495(sacB_1) NCTC11468_00497(sacB_2)

ANS:	ArsFIN_09060(sacB_1) ArsFIN_33900(sacB_2)

AET:	LDL57_02795

AAPC:

QG404_04625 QG404_11430

VNA:	PN96_15895

VEJ:	VEJY3_24001

VOS:	KNV97_12390

PST:	PSPTO_1453(lsc-1) PSPTO_2305(lsc-2) PSPTO_A0032(lsc-3)

PSB:	Psyr_0754 Psyr_2103

PSYR:

N018_09840 N018_21915

PSP:	PSPPH_2074 PSPPH_4994 PSPPH_A0027

PAMG:

BKM19_005625 BKM19_020905

PAVL:

BKM03_17755 BKM03_30235

PVD:	CFBP1590__2153(lsc)

PCOF:

POR16_09640 POR16_11105

PTRE:

I9H09_13885 I9H09_15130 I9H09_26515

PSYI:

MME58_10780

PAST:

N015_16390

PFE:	PSF113_5195(m1ft)

PZA:	HU749_026375

PFS:	PFLU_2294(lsc)

PFC:	PflA506_2166(lsc)

PPZ:	H045_06560 H045_11010

PTV:	AA957_03125

PVR:	PverR02_12020

POI:	BOP93_09725

PRX:	HRH33_11200

PMAB:

U0037_11525

PBA:	PSEBR_a4994

PBC:	CD58_26170

PSK:	U771_12360

PCH:	EY04_25410

PCZ:	PCL1606_12540

PCP:	JM49_06275

PCHP:

C4K32_5099

PSEM:

TO66_25485

PVK:	EPZ47_15010 EPZ47_26275

PBZ:	GN234_21905

PTRT:

HU722_0011780

PSAM:

HU731_026165

PASG:

KSS96_12280

PPAE:

LDL65_14825

PRHZ:

CRX69_07400

PSKU:

KUIN1_07670 KUIN1_20930

PHEF:

PSH57_03295

PLIS:

NN484_06275

PBEJ:

PSH84_25045

PBAM:

NUH87_11835

PQE:	OSC50_14425

ACX:	Achr_16320

PCAR:

PC2016_2073

PXSI:

EJ103_18095

SALM:

D0Y50_07165

ZPL:	ZBT109_0061 ZBT109_0692 ZBT109_1224 ZBT109_2596 ZBT109_2698 ZBT109_2699 ZBT109_2700

CDIZ:

CEDIAZO_00298(sacB)

CCAX:

KZ686_23300

BMA:	BMAA0466(sacB)

BMV:	BMASAVP1_0714(sacB)

BML:	BMA10229_1010(sacB)

BMN:	BMA10247_A1984(sacB)

BMAZ:

BM44_4010(lsdA)

BMAL:

DM55_4050(lsdA)

BMAQ:

DM76_4747(lsdA)

BMAI:

DM57_13175

BMAF:

DM51_4192(lsdA)

BMAB:

BM45_4787(lsdA)

BPS:

BPSS0543

BPM:	BURPS1710b_A2102(sacB)

BPL:	BURPS1106A_A0735(sacB)

BPD:	BURPS668_A0822(sacB)

BPSE:

BDL_3771(lsdA)

BPSU:

BBN_3943(lsdA)

BPSD:

BBX_5608(lsdA)

BPZ:	BP1026B_II0600

BPQ:	BPC006_II0780

BPK:	BBK_3948(lsdA)

BPSH:

DR55_4808(lsdA)

BPSA:

BBU_5503(lsdA)

BPSO:

X996_3722(lsdA)

BUT:	X994_4076(lsdA)

BTE:	BTH_II1872

BTQ:	BTQ_5156(lsdA)

BTJ:	BTJ_3784(lsdA)

BTZ:	BTL_4642(lsdA)

BTD:	BTI_5372(lsdA)

BTV:	BTHA_5587(lsdA)

BTHE:

BTN_4281(lsdA)

BTHM:

BTRA_3812(lsdA)

BTHA:

DR62_4330

BTHL:

BG87_4613(lsdA)

BOK:	DM82_4647(lsdA)

BOC:	BG90_5946(lsdA)

BHG:	I6G56_25325

BUD:	AQ610_27930

BVI:	Bcep1808_4836

BVE:	AK36_4082(lsdA)

BCM:	Bcenmc03_3247

BCH:	Bcen2424_4270

BCJ:

BCAM1405

BCEW:

DM40_4293(lsdA)

BCEO:

I35_5258

BAM:	Bamb_3698 Bamb_6116

BAC:	BamMC406_4171

BCT:

GEM_4344

BCED:

DM42_3682(lsdA)

BCEP:

APZ15_17605

BPYR:

ABD05_29140

BCON:

NL30_05610

BUB:	BW23_5090(lsdA)

BDF:	WI26_20045

BLAT:

WK25_23835

BTEI:

WS51_04730

BSEM:

WJ12_26850

BMEC:

WJ16_25440

BSTG:

WT74_25820

BAEN:

L3V59_20215

BSER:

R0290_26260

BUK:

MYA_4384

BUL:	BW21_5054(lsdA)

BURK:

DM992_18855

BURM:

GJG85_18210

BPH:

Bphy_6047

PTS:	CUJ90_24145

TCAR:

U0034_10420

BID:

Bind_2021

CAK:

Caul_0964

CSE:

Cseg_0465

BRL:	BZG35_16745

RED:	roselon_03017

NSM:	JO391_16820

HBC:	AEM38_01240

ZMO:	ZMO0374 ZMO0375

ZMN:	Za10_0866 Za10_0867

ZMM:	Zmob_0914 Zmob_0915

ZMB:	ZZ6_0874 ZZ6_0875

ZMI:	ZCP4_0897 ZCP4_0898

ZMC:	A265_00888(sacC) A265_00889(sacB)

ZMR:	A254_00888(sacC) A254_00889(sacB)

ZMP:	Zymop_0827 Zymop_0828

NAR:

Saro_1879

NPP:	PP1Y_AT36439

NPN:	JI59_03150

NRE:	BES08_10070

NOV:	TQ38_014200

NOT:	C7W88_12270 C7W88_21645

NOR:	FA702_19790 FA702_20925

NGF:	FRF71_03510

NCP:	U0041_12285

SMAG:

AN936_02485

STAX:

MC45_01245

SPHI:

TS85_13025

SNJ:	A7E77_11610

SMY:	BJP26_16575

SPAN:

AWL63_03220

SPLK:

AV944_13330

SPAU:

DRN02_006190

SLAN:

GV829_10845

SBIN:

SBA_ch1_19140(lsc-3)

SSAG:

KV697_04550

SAAP:

E2E30_02860

SCH:	Sphch_2587

SSY:

SLG_08170

SPHR:

BSY17_3143

SHYD:

CJD35_17155

SYA:	A6768_10910

SAMI:

SAMIE_1023310

BLAS:

BSY18_2543 BSY18_3408

BFW:	B5J99_03675 B5J99_07835

ALH:	G6N82_05250

AAY:	WYH_00345(sacB)

ANH:	A6F65_00742(sacB)

QGE:	K3136_05835

ELI:

ELI_04235

PNS:	A9D12_08370

PORL:

BG023_111186

PHZ:	CHX26_06545

POT:	E2E27_16180

GOX:

GOX0873

GOH:

B932_1297

GOY:	GLS_c09570(sacB)

GAL:	A0U94_11845

GTI:	FXF46_04755

GSP:	IGS75_05290

GFA:	MKW11_04725

GDI:	GDI0476(lsdA)

GDJ:

Gdia_1531

KNA:	B0W47_08430

KSC:	CD178_02917(lsdA)

AACE:

A0U92_09740

ABG:	Asbog_02356

KBA:	A0U89_12650

NCH:	A0U93_08715

NTN:	D5366_01955

NCB:	C0V82_01290

BSU:	BSU34450(sacB)

BSR:

I33_3564

BSL:

A7A1_2664

BSH:	BSU6051_34450(sacB)

BSY:	I653_16750

BSUT:

BSUB_03673(sacB)

BSUL:

BSUA_03673(sacB)

BSUS:

Q433_18865

BSO:	BSNT_10031(sacB)

BSN:	BSn5_08155

BSQ:	B657_34450(sacB)

BSX:	C663_3329(sacB)

BSP:	U712_17245

BSS:	BSUW23_16930(sacB)

BST:

GYO_3780

BIT:	BIS30_06895

BLI:	BL02216(sacB)

BLD:	BLi03706(sacB)

BLH:	BaLi_c37120(sacB)

BAY:	RBAM_037650

BAQ:	BACAU_3773(sacB)

BYA:	BANAU_3942(sacB)

BQY:	MUS_4456(sacB)

BAMP:

B938_19305

BAML:

BAM5036_3682(sacB)

BAMA:

RBAU_3886(sacB)

BAMN:

BASU_3670(sacB)

BAMB:

BAPNAU_3951(sacB)

BAMT:

AJ82_21245

BAMY:

V529_40280(sacB)

BMP:	NG74_03943(sacB)

BAO:	BAMF_3880(sacB)

BAZ:	BAMTA208_20465(sacB)

BQL:

LL3_04208

BXH:	BAXH7_04197(sacB)

BAMI:

KSO_000250

BAMC:

U471_39220

BAMF:

U722_20025

BSIA:

CWD84_00405

BAE:	BATR1942_15170

BVM:	B9C48_19215

BSON:

S101395_00700(sacB)

BHT:	DIC78_13815

BMOJ:

HC660_33370(sacB)

BTEQ:

G4P54_17695(sacB)

BIQ:	AN935_17335

BSTR:

QI003_20690(sacB)

BGY:	BGLY_4101(sacB)

BCAB:

EFK13_17675(sacB)

BRY:	M0696_17360(sacB)

BJS:

MY9_3489

BACP:

SB24_09955

BACB:

OY17_02500

BACY:

QF06_15600

BACL:

BS34A_37530(sacB)

BALM:

BsLM_3451

BACS:

AUL54_11010

BACQ:

DOE78_02405 DOE78_02410 DOE78_02415

BASB:

M662_03450

BCIR:

C2I06_01405

BMQ:	BMQ_1554(sacB) BMQ_1586(sacB)

BMD:	BMD_1536(sacB) BMD_1568(sacB)

BMH:	BMWSH_3639 BMWSH_3674(sacB)

BMEG:

BG04_3845(sacB) BG04_3876(sacB)

BEO:

BEH_00970

BFX:	BC359_01540

PKS:	IE339_14315

BKW:	BkAM31D_09515(sacC_2) BkAM31D_09520(sacB_1) BkAM31D_09525(sacB_2)

BGI:	BGM20_11345

HMN:	HM131_02710 HM131_02715

TAP:	GZ22_13470

FPN:	ABE65_018845

FEC:	QNH15_01910

BSJ:	UP17_13710

PFRI:

L8956_14195

GRC:	GI584_03495

NDT:	L1999_14380

MEKU:

HUW50_07230

MSEM:

GMB29_01950

MDG:	K8L98_01625

RMF:	D5E69_21855

RAZ:	U9J35_03300

ROSS:

V2W31_03375

DOM:	RRU94_03985

STEA:

C0679_02050

BFM:	BP422_21515 BP422_21520 BP422_21525

PPY:

PPE_00681

PPM:	PPSC2_03770(sacB)

PPO:	PPM_0698(sacB)

PPOL:

X809_03305

PPQ:	PPSQR21_007310

PPOY:

RE92_08215

PTA:	HPL003_11340

PSAB:

PSAB_15175 PSAB_15180

PDU:	PDUR_14695 PDUR_14700

PGM:	PGRAT_31830

POD:	PODO_09600

PSTE:

PSTEL_16705

PAEH:

H70357_04830

PBJ:	VN24_00465 VN24_00470

PRI:	PRIO_6667(sacB)

PSON:

JI735_08010

PPEO:

ABE82_03540

PBV:	AR543_09605

PDH:	B9T62_10830 B9T62_31080

PKB:	B4V02_21625

PAIH:

ASL14_08295

PBK:	Back11_27580(sacB)

PSOP:

KP014_18030 KP014_18035

PKA:	PQ456_07025

PPOG:

QPK24_03535

PHK:	SK066_16340

PNK:	AASFL403_12305

PLZH:

C0638_04175

PACL:

DCC85_09225

SMU:	SMU_2028(sacB)

LFD:	QFX10_03180

AAPN:

AAPFHON13_02230

LKN:	FGL74_01900 FGL74_01905

CAC:	CA_C1772(sacB1)

CAE:	SMB_G1797(sacB1)

CAY:	CEA_G1784(sacB1)

CPAS:

Clopa_3796 Clopa_4677 Clopa_4678 Clopa_4679

CPAT:

CLPA_c03870(sacB1) CLPA_c05690(sacB2) CLPA_c06780(sacB3) CLPA_c10840(lsc)

CPAE:

CPAST_c03870(sacB1) CPAST_c05690(sacB2) CPAST_c06780(sacB3) CPAST_c10840(lsc)

EHA:	Ethha_2381

SFZ:	SFLOR_v1c07270(sacB)

SCB:	SCAB_18831

SXI:	SXIM_02300

STRC:

AA958_04345

SGE:	DWG14_00170(sacC_1)

SROI:

IAG44_00865

LXL:	KDY119_03067(sacB)

CMI:	CMM_0614(sacB)

CMS:

CMS2823

CMC:	CMN_00575(sacB)

CCAP:

AES38_02540

CCAF:

FGD68_05160

MHOS:

CXR34_02450

RTN:	A6122_1991

RRY:	C1O28_03100

RIA:	C7V51_03695

AGY:	ATC03_04550

CART:

PA27867_1284

CRY:	B7495_14670

MANT:

BHD05_02545

AGX:	AGREI_2513(lsdA)

ART:

Arth_0405

ARR:	ARUE_c13170(lsdA)

ARW:	MB46_03655

ARH:	AHiyo8_16260

ARQ:	BWQ92_07880

ARN:	CGK93_07280

ARX:	ARZXY2_2636(sacB)

ARTH:

C3B78_00405

AOD:	Q8Z05_10125

ARTZ:

FCN77_02600

ARTQ:

CGQ24_14225

AAU:	AAur_1402(sacB)

PUE:	FV140_06900

PNV:	JMY29_06575

PAYJ:

HMI59_14780

PAGO:

IRJ34_06670

ARZ:	AUT26_06110

ACH:

Achl_0616

APN:	Asphe3_05080

PSUL:

AU252_07885

PSNI:

NIBR502771_02570

PSEY:

GU243_18645

POK:	SMD14_00595

PSLS:

KTR40_00280

GAR:	AOZ07_05555

GMI:	NMP99_05715

GMY:

XH9_03535

GLM:	N6V40_14775

RTER:

IDM49_08725

PAEY:

KUF55_04885

BSAU:

DWV08_16410

BRR:	C1N80_02640

BRHA:

NLU66_02890

CFL:

Cfla_3405

CELH:

GXP71_08935

PSOI:

PCC79_00130

NOQ:	LN652_16535

NOA:	BKM31_20080

NOW:	GBF35_14590

NGN:	LCN96_26345

NFS:	OIE67_16660

MCAY:

PVK37_26270

MICF:

QQG74_15470

AOS:	AXE84_01300

ARD:	AXF14_07845

ANE:	ATCC27039_03610(sacB)

AHW:	NCTC11636_00957(lsdA)

ASLA:

NCTC11923_00200(lsdA)

AVC:	NCTC10951_00161(lsdA)

ACHN:

JJJ14_03670

DAB:	AUC44_09710

UAM:	UABAM_02711

HJE:	HacjB3_04715

HARA:

AArcS_1170

HMA:	rrnAC1478(sacB)

HHI:	HAH_2052(sacB)

HHN:	HISP_10450

HAB:	SG26_02760

HTA:	BVU17_10010

HALJ:

G9465_15150

HSIN:

KDQ40_03175

HMU:

Hmuk_1938

HALZ:

E5139_12805

HALL:

LC1Hm_1260(sacB)

HAZP:

GBQ70_12820

HRR:	HZS55_13745

HGI:	ABY42_09080

HLM:	DV707_13530

HALM:

FCF25_01025

HLA:

Hlac_2488

HALP:

DOS48_12610

HALB:

EKH57_05865

HEZZ:

EO776_06640

HALQ:

Hrr1229_008425

HSS:	J7656_06790

SRUB:

C2R22_17630

HAE:	halTADL_1914

HMP:	K6T50_07700

HRE:	K6T36_07520

HRM:	K6T25_08275

HDF:	AArcSl_0936(sacB)

HTU:

Htur_4097

HSAL:

JMJ58_05410

NOU:	Natoc_3599

HLR:	HALLA_03955

NAS:	GCU68_19505

» show all

Reference

1 [PMID:24540594]

Authors

HEHRE EJ

Title

Enzymic synthesis of polysaccharides: a biological type of polymerization.

Journal

Adv Enzymol Relat Subj Biochem 11:297-337 (1951)
DOI:10.1002/9780470122563.ch6

Reference

2 [PMID:13363847]

Authors

AVIGAD G, FEINGOLD DS, HESTRIN S.

Title

The mechanism of polysaccharide production from sucrose. 3. Donor-acceptor specificity of levansucrase from Aerobacter levanicum.

Journal

Biochem J 64:340-51 (1956)
DOI:10.1042/bj0640340

Reference

3 [PMID:5940635]

Authors

Reese ET, Avigad G.

Title

Purification of levansucrase by precipitation with levan.

Journal

Biochim Biophys Acta 113:79-83 (1966)
DOI:10.1016/s0926-6593(66)80123-6

Reference

4 [PMID:14517548]

Authors

Meng G, Futterer K

Title

Structural framework of fructosyl transfer in Bacillus subtilis levansucrase.

Journal

Nat Struct Biol 10:935-41 (2003)
DOI:10.1038/nsb974

Sequence

[bsu:BSU34450]

Other DBs

ExplorEnz - The Enzyme Database:

2.4.1.10

IUBMB Enzyme Nomenclature:

2.4.1.10

ExPASy - ENZYME nomenclature database:

2.4.1.10

BRENDA, the Enzyme Database:

2.4.1.10

CAS:

9030-17-5

DBGET integrated database retrieval system