KEGG   ENZYME: 2.4.1.117Help
Entry
EC 2.4.1.117                Enzyme                                 

Name
dolichyl-phosphate beta-glucosyltransferase;
polyprenyl phosphate:UDP-D-glucose glucosyltransferase;
UDP-glucose dolichyl-phosphate glucosyltransferase;
uridine diphosphoglucose-dolichol glucosyltransferase;
UDP-glucose:dolichol phosphate glucosyltransferase;
UDP-glucose:dolicholphosphoryl glucosyltransferase;
UDP-glucose:dolichyl monophosphate glucosyltransferase;
UDP-glucose:dolichyl phosphate glucosyltransferase;
UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:dolichyl-phosphate beta-D-glucosyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-alpha-D-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate [RN:R01005]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucose [CPD:C00029];
dolichyl phosphate [CPD:C00110]
Product
UDP [CPD:C00015];
dolichyl beta-D-glucosyl phosphate [CPD:C01246]
Comment
Solanesyl phosphate and ficaprenyl phosphate can act as acceptors, but more slowly.
History
EC 2.4.1.117 created 1984
Pathway
ec00510  N-Glycan biosynthesis
ec01100  Metabolic pathways
Orthology
K00729  dolichyl-phosphate beta-glucosyltransferase
Genes
HSA: 29880(ALG5)
PTR: 452541(ALG5)
PPS: 100986837(ALG5)
GGO: 101140850(ALG5)
PON: 100446264(ALG5)
NLE: 100584956(ALG5)
MCC: 694836(ALG5)
MCF: 102136561(ALG5)
CSAB: 103214290(ALG5)
RRO: 104677936(ALG5)
RBB: 108516575(ALG5)
CJC: 100405365(ALG5)
SBQ: 101037187(ALG5)
MMU: 66248(Alg5)
RNO: 295051(Alg5)
CGE: 100769679(Alg5)
NGI: 103745206(Alg5)
HGL: 101713618(Alg5)
CCAN: 109699656(Alg5)
OCU: 100341569(ALG5)
TUP: 102493005(ALG5)
CFA: 477301(ALG5)
AML: 100466955(ALG5)
UMR: 103664420(ALG5)
ORO: 101369419(ALG5)
FCA: 101086366(ALG5)
PTG: 102967667(ALG5)
AJU: 106973819(ALG5)
BTA: 506566(ALG5)
BOM: 102277530(ALG5)
BIU: 109566770(ALG5)
PHD: 102338723(ALG5)
CHX: 102185475(ALG5)
OAS: 101108665(ALG5)
SSC: 100154411(ALG5)
CFR: 102520513(ALG5)
CDK: 105100803(ALG5)
BACU: 103016579(ALG5)
LVE: 103069762(ALG5)
OOR: 101280951(ALG5)
ECB: 100065925(ALG5)
EPZ: 103557957(ALG5)
EAI: 106844938(ALG5)
MYB: 102244156(ALG5)
MYD: 102775111(ALG5)
HAI: 109388464(ALG5)
RSS: 109449880(ALG5)
PALE: 102889415(ALG5)
LAV: 100676231(ALG5)
TMU: 101344927
MDO: 100027286(ALG5)
SHR: 100921245(ALG5)
OAA: 100080881(ALG5)
GGA: 418898(ALG5)
MGP: 100540420(ALG5)
CJO: 107308214(ALG5)
APLA: 101803230(ALG5)
ACYG: 106043251(ALG5)
TGU: 100228219(ALG5)
GFR: 102033771(ALG5)
FAB: 101812478(ALG5)
PHI: 102113352(ALG5)
PMAJ: 107203080(ALG5)
CCW: 104689929(ALG5)
FPG: 101911530(ALG5)
FCH: 102054078(ALG5)
CLV: 102088946(ALG5)
EGZ: 104131316(ALG5)
AAM: 106500357(ALG5)
ASN: 102388117(ALG5)
AMJ: 102569010(ALG5)
PSS: 102448326(ALG5)
CMY: 102941300(ALG5)
CPIC: 101947359(ALG5)
ACS: 100559641(alg5)
PVT: 110070720(ALG5)
PBI: 103051824(ALG5)
XLA: 379570(alg5.S) 380326(alg5.L)
XTR: 448472(alg5)
NPR: 108785076(ALG5)
DRE: 751635(alg5)
SRX: 107728859 107734448(alg5)
SANH: 107686163(alg5) 107697411
IPU: 108276693(alg5)
AMEX: 103040236(alg5)
TRU: 101075614(alg5)
LCO: 104928220(alg5)
NCC: 104964551(alg5)
MZE: 101471073(alg5)
OLA: 101167889(alg5)
XMA: 102218893(alg5)
PRET: 103475558(alg5)
NFU: 107391188(alg5)
CSEM: 103395220(alg5)
LCF: 108893721(alg5)
HCQ: 109517274(alg5)
BPEC: 110158484(alg5)
ELS: 105029972(alg5)
SFM: 108936209(alg5)
LCM: 102367426(ALG5)
CMK: 103177190(alg5)
CIN: 100183398
SPU: 578155
APLC: 110979824
SKO: 100373804
DME: Dmel_CG7870(wol)
DSI: Dsimw501_GD22423(Dsim_GD22423)
MDE: 101900105
AAG: 5576963
AME: 100576818
BIM: 100749176
BTER: 100649565
AEC: 105153947
ACEP: 105618063
PBAR: 105433034
HST: 105189751
CFO: 105255263
LHU: 105679528
PGC: 109859947
NVI: 100119751
TCA: 663943
DPA: 109541663
NVL: 108565377
BMOR: 101738398
PRAP: 111001741
API: 100158832
DNX: 107168049
ZNE: 110829684
FCD: 110851238
TUT: 107366120
CEL: CELE_H43I07.3(H43I07.3)
CBR: CBG01437
BMY: Bm1_17955
TSP: Tsp_09221
CRG: 105336534
MYI: 110454819
OBI: 106869719
LAK: 106181301
SHX: MS3_07190
EGL: EGR_01390
EPA: 110240535
ADF: 107357552
HMG: 100201682
AQU: 100633549
ATH: AT2G39630
CRB: 17889109
THJ: 104824275
CPAP: 110823920
CIT: 102620481
TCC: 18586096
EGR: 104454295
VRA: 106758619
VAR: 108321745
CCAJ: 109802432
CAM: 101510555
LJA: Lj1g3v3233410.1(Lj1g3v3233410.1)
ADU: 107486935
AIP: 107635673
LANG: 109354923
FVE: 101312675
PPER: 18786650
PMUM: 103332650
PAVI: 110756749
MDM: 103445584
CPEP: 111781841
RCU: 8267771
JCU: 105647703
VVI: 100261575
SLY: 101264522
SPEN: 107018869
SOT: 102582503
CANN: 107870236
NSY: 104249533
NTO: 104088655
SIND: 105171912
HAN: 110904734
DCR: 108211023
SOE: 110794836
OSA: 4334604
DOSA: Os03t0821800-01(Os03g0821800)
OBR: 102709915
BDI: 100842934
ATS: 109765191(LOC109765191)
SBI: 110431840
ZMA: 100273013(cl30871_1)
SITA: 101761730
MUS: 103999918
ATR: 18436078
CRE: CHLREDRAFT_18353(GTR4)
APRO: F751_1702
SCE: YPL227C(ALG5)
ERC: Ecym_2162
KMX: KLMA_70223(ALG5)
NCS: NCAS_0G01290(NCAS0G01290)
NDI: NDAI_0F01420(NDAI0F01420)
TPF: TPHA_0E02660(TPHA0E02660)
TBL: TBLA_0A02190(TBLA0A02190)
TDL: TDEL_0F01850(TDEL0F01850)
KAF: KAFR_0F01230(KAFR0F01230)
PIC: PICST_57548(ALG5)
CAL: CAALFM_CR02790CA(ALG5)
CAUR: QG37_02990
SLB: AWJ20_3672(ALG5)
NCR: NCU06386
NTE: NEUTE1DRAFT60321(NEUTE1DRAFT_60321)
MGR: MGG_06137
SSCK: SPSK_03383
MAW: MAC_01305
MAJ: MAA_06326
CMT: CCM_07183
BFU: BCIN_01g00340(Bcalg5)
MBE: MBM_00624
ANI: AN7715.2
ANG: ANI_1_526034(An03g04410)
ABE: ARB_07101
TVE: TRV_04917
PTE: PTT_12170
SPO: SPBC56F2.10c(alg5)
ABP: AGABI1DRAFT35803(AGABI1DRAFT_35803)
ABV: AGABI2DRAFT70879(AGABI2DRAFT_70879)
MGL: MGL_2489
DDI: DDB_G0288321(dgtA)
CPV: cgd5_2590
SMIN: v1.2.007750.t1(symbB.v1.2.007750.t1)
SPAR: SPRG_13122
 » show all
Taxonomy
Reference
1  [PMID:5273893]
  Authors
Behrens NH, Leloir LF.
  Title
Dolichol monophosphate glucose: an intermediate in glucose transfer in liver.
  Journal
Proc Natl Acad Sci U S A 66:153-9 (1970)
DOI:10.1073/pnas.66.1.153
Reference
2  [PMID:849929]
  Authors
Herscovics A, Bugge B, Jeanloz RW.
  Title
Glucosyltransferase activity in calf pancreas microsomes. Formation of dolichyl D[14C]glucosyl phosphate and 14C-labeled lipid-linked oligosaccharides from UDP-D-[14C]glucose.
  Journal
J Biol Chem 252:2271-7 (1977)
Reference
3  [PMID:438216]
  Authors
Villemez CL, Carlo PL.
  Title
Properties of a soluble polyprenyl phosphate: UDP-D-glucose glucosyltransferase.
  Journal
J Biol Chem 254:4814-9 (1979)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.117
IUBMB Enzyme Nomenclature: 2.4.1.117
ExPASy - ENZYME nomenclature database: 2.4.1.117
BRENDA, the Enzyme Database: 2.4.1.117
CAS: 71061-42-2

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