KEGG   ENZYME: 2.4.1.159Help
Entry
EC 2.4.1.159                Enzyme                                 

Name
flavonol-3-O-glucoside L-rhamnosyltransferase;
uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase;
UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase;
UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-beta-L-rhamnose:flavonol-3-O-beta-D-glucoside 6''-O-L-rhamnosyltransferase (configuration-inverting)
Reaction(IUBMB)
UDP-beta-L-rhamnose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] [RN:R03880]
Reaction(KEGG)
Substrate
UDP-beta-L-rhamnose [CPD:C02199];
flavonol 3-O-beta-D-glucoside [CPD:C03946]
Product
UDP [CPD:C00015];
flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] [CPD:C04194]
Comment
A configuration-inverting rhamnosyltransferase that converts flavonol 3-O-glucosides to 3-O-rutinosides. Also acts, more slowly, on rutin, quercetin 3-O-galactoside and flavonol 3-O-rhamnosides.
History
EC 2.4.1.159 created 1986, modified 2015
Pathway
ec00944  Flavone and flavonol biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K22772  flavonol-3-O-glucoside L-rhamnosyltransferase
Genes
CPAP: 110821584
CIT: 102578019
CIC: CICLE_v10004868mg
GRA: 105803319
GHI: 107912543
DZI: 111313488
GMX: 100818062(FG1) 100819964(UGT79A6) 102663988
PVU: PHAVU_007G135800g
VRA: 106769849
VAR: 108340918
CCAJ: 109804959
CAM: 101512184(UGT79A5)
ADU: 107466489
AIP: 107619647
LANG: 109336024
RCU: 8271431
HBR: 110646224
POP: 7465981
SLY: 101244316
SPEN: 107031550
SOT: 102581417
CANN: 107861697
NSY: 104213556
SIND: 105170545
LSV: 111885539
CCAV: 112518423
DOSA: Os11t0457300-01(Os11g0457300) Os11t0461200-01(Os11g0461200)
OBR: 102707242
ATS: 109761553(LOC109761553)
ZMA: 100192114
PDA: 103698348
DCT: 110100597
PEQ: 110020195
AOF: 109839485
 » show all
Taxonomy
Reference
1
  Authors
Kleinehollenhorst, G., Behrens, H., Pegels, G., Srunk, N. and Wiermann, R.
  Title
Formation of flavonol 3-O-diglycosides and flavonol 3-O-triglycosides by enzyme extracts from anthers of Tulipa cv apeldoorn - characterization and activity of 3 different O-glycosyltransferases during anther development.
  Journal
Z Natursforsch C: Biosci 37:587-599 (1982)
Reference
2  [PMID:12900416]
  Authors
Jones P, Messner B, Nakajima J, Schaffner AR, Saito K.
  Title
UGT73C6 and UGT78D1, glycosyltransferases involved in flavonol glycoside biosynthesis in Arabidopsis thaliana.
  Journal
J Biol Chem 278:43910-8 (2003)
DOI:10.1074/jbc.M303523200
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.159
IUBMB Enzyme Nomenclature: 2.4.1.159
ExPASy - ENZYME nomenclature database: 2.4.1.159
BRENDA, the Enzyme Database: 2.4.1.159
CAS: 83380-89-6

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