KEGG   ENZYME: 2.4.1.180Help
Entry
EC 2.4.1.180                Enzyme                                 

Name
lipopolysaccharide N-acetylmannosaminouronosyltransferase;
ManNAcA transferase;
uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase;
UDP-N-acetyl-beta-D-mannosaminouronate:lipid I N-acetyl-beta-D-mannosaminouronosyltransferase (incorrect)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-N-acetyl-alpha-D-mannosaminouronate:lipid I N-acetyl-alpha-D-mannosaminouronosyltransferase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-mannosaminouronate + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = UDP + N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R04477]
Reaction(KEGG)
Substrate
UDP-N-acetyl-alpha-D-mannosaminouronate;
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C01289]
Product
UDP [CPD:C00015];
N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Comment
Involved in the biosynthesis of common antigen in Enterobacteriaceae.
History
EC 2.4.1.180 created 1990, modified 2011
Orthology
K02852  UDP-N-acetyl-D-mannosaminouronate:lipid I N-acetyl-D-mannosaminouronosyltransferase
Genes
ECO: b3794(wecG)
ECJ: JW3770(rffM)
ECD: ECDH10B_3984(rffM)
EBW: BWG_3477(rffM)
ECOK: ECMDS42_3233(rffM)
ECE: Z5306(wecG)
ECS: ECs4728
ECF: ECH74115_5228
ETW: ECSP_4843
ELX: CDCO157_4465
EOJ: ECO26_4791(rffM)
EOI: ECO111_4621(rffM)
EOH: ECO103_4369(rffM)
ECOO: ECRM13514_4855(wecG)
ECOH: ECRM13516_4640(wecG)
ECG: E2348C_4096(rffM)
EOK: G2583_4589(rffM)
ESO: O3O_00450
ESM: O3M_24810
ESL: O3K_24890
ELH: ETEC_4077
ECC: c4716(wecG)
ECP: ECP_3986
ECI: UTI89_C4352(rffM)
ECV: APECO1_2680(wecG)
ECY: ECSE_4078
ECR: ECIAI1_3982(rffM)
ECQ: ECED1_4480(rffM)
ECK: EC55989_4267(rffM)
ECT: ECIAI39_2992(rffM)
EOC: CE10_4438(rffM)
EUM: ECUMN_4320(rffM)
ECZ: ECS88_4218(rffM)
ELO: EC042_4172(rffM)
ESE: ECSF_3635
EBR: ECB_03673(wecG)
EBD: ECBD_4244
EKF: KO11_03985(rffM)
EAB: ECABU_c42740(rffM)
EDJ: ECDH1ME8569_3677(rffM)
ENA: ECNA114_3933(wecG)
ELW: ECW_m4093(rffM)
ELL: WFL_19985(rffM)
ELC: i14_4309(wecG)
ELD: i02_4309(wecG)
ELP: P12B_c3925(wecG)
EBL: ECD_03673(wecG)
EBE: B21_03622(rffM)
ELF: LF82_1862(rffM)
ECOI: ECOPMV1_04128(tagA)
ECOJ: P423_21000
ECOS: EC958_4257(rffM)
EFE: EFER_3709(rffM)
STY: STY3626(rffM)
STT: t3368(rffM)
STM: STM3929(wecG)
SEO: STM14_4727(wecG)
SEY: SL1344_3888(rffM)
SEJ: STMUK_3915(wecG)
SEB: STM474_4107(wecG)
SEF: UMN798_4266(rffM)
SENR: STMDT2_38001(rffM)
SEND: DT104_39471(rffM)
SENI: CY43_20570
SPT: SPA3769(rffM)
SEK: SSPA3513
SEI: SPC_4043(rffM)
SEC: SCH_3834(wecG)
SHB: SU5_045
SENS: Q786_19255
SED: SeD_A4317
SEG: SG3514(wecG)
SEL: SPUL_3497(wecG)
SEGA: SPUCDC_3483(wecG)
SET: SEN3734(wecG)
SENA: AU38_19270
SENO: AU37_19265
SENV: AU39_19285
SENQ: AU40_21490
SENL: IY59_19740
SEEP: I137_16765
SENE: IA1_19100
SBG: SBG_3472(rffM)
SBZ: A464_3989
SFL: SF3869(wecG)
SFX: S3891(wecG)
SFV: SFV_3709(wecG)
SFE: SFxv_4215(rffM)
SFN: SFy_5523
SFS: SFyv_5588
SFT: NCTC1_04181(tagA)
SSN: SSON_3967(wecG)
SBO: SBO_3806(wecG)
SDY: SDY_3953(wecG)
ENC: ECL_04992
ECLO: ENC_02090
EEC: EcWSU1_04378(wecG)
ECLX: LI66_00870
ECLY: LI62_01285
ECLZ: LI64_00945
ESA: ESA_03765
CSK: ES15_3690(rffM)
CTU: CTU_02310(wecG)
KPN: KPN_04295(wecG)
KPU: KP1_0157(wecG)
KPP: A79E_4893
KPE: KPK_5384
KPR: KPR_0249(wecG)
KPJ: N559_4990
KPX: PMK1_01782(tagA)
KPNU: LI86_25805
KPNK: BN49_4564(wecG)
KVA: Kvar_4933
KOX: KOX_07600
KOE: A225_0163
EAE: EAE_07840
EAR: CCG32431
CKO: CKO_00136
CRO: ROD_39521(rffM)
CAMA: F384_20605
EBF: D782_4358
PSTS: E05_20660
YPE: YPO3855(wecG)
YPK: y0373(wecG)
YPH: YPC_0367(rffM)
YPA: YPA_0163
YPN: YPN_0108
YPM: YP_3190(wecG)
YPZ: YPZ3_3409(wecG)
YPD: YPD4_3401(wecG)
YPX: YPD8_3401(wecG)
YPW: CH59_1798
YPJ: CH55_3155
YPV: BZ15_3853
YPL: CH46_1206
YPS: YPTB0179(wecG)
YPO: BZ17_2410
YPY: YPK_4022
YPB: YPTS_0191
YPQ: DJ40_2245
YPU: BZ21_3530
YPR: BZ20_1946
YPC: BZ23_3802
YPF: BZ19_3637
YEN: YE0180(rffM)
YEY: Y11_33781
YEW: CH47_3305
YET: CH48_1873
YEE: YE5303_41241(rffM)
YAL: AT01_2291
YFR: AW19_3027
YIN: CH53_1983
YKR: CH54_2761
YRO: CH64_2769
YRU: BD65_1767
SPE: Spro_0172
SRL: SOD_c01280(wecG)
SPLY: Q5A_000735(wecG)
SMAF: D781_0140
SMW: SMWW4_v1c01820(rffM)
SMAR: SM39_4328(rffM)
SMAC: SMDB11_4276(rffM)
SERF: L085_05280
RAA: Q7S_21620
ECA: ECA4200(wecG)
PATR: EV46_20950
PATO: GZ59_42640(wecG)
PCT: PC1_4000
PEC: W5S_4355
SGL: SG2374
SOD: Sant_0300(rffM)
PES: SOPEG_0373(rffM)
DDD: Dda3937_00277(rffM)
DDQ: DDI_3997
ETA: ETA_02080(wecG)
EPY: EpC_01960(wecG)
EPR: EPYR_00205(wecG)
EAM: EAMY_0182(wecG)
EAY: EAM_0175(wecG)
EBI: EbC_02050(wecG)
ERJ: EJP617_13940(wecG)
EGE: EM595_3325(wecG)
PAM: PANA_0158(wecG)
PLF: PANA5342_4269(wecG)
PAJ: PAJ_3318(wecG)
PVA: Pvag_3393(wecG)
PSTW: DSJ_22155
TPTY: NCTC11468_03531(tagA)
PLU: plu4651(wecG)
PAY: PAU_04131(wecG)
PMR: PMI3327(rffM)
PMIB: BB2000_3359(rffM)
XBO: XBJ1_4167(rffM)
XBV: XBW1_4522(wecG)
XNE: XNC1_0396(rffM)
XNM: XNC2_0388(rffM)
XDO: XDD1_0357(wecG)
XPO: XPG1_3473(wecG)
PSI: S70_11695
PSX: DR96_841
PRG: RB151_042090(wecG)
PHEI: NCTC12003_03728(tagA)
MMK: MU9_244
ETR: ETAE_0112(wecG)
ETD: ETAF_0085
ETE: ETEE_1873
LRI: NCTC12151_03582(tagA)
PSHI: SAMEA2665130_3004(tagA)
HDU: HD_1833(wecG)
HAP: HAPS_1059(wecG)
HPAZ: K756_01480
HPAS: JL26_00605
HPAK: JT17_09615
MHQ: D650_2570
MHAT: B824_3630
MHX: MHH_c03420(wecG)
MHAE: F382_09245
MHAM: J450_05970
MHAO: J451_06990
MHAL: N220_12970
MHAQ: WC39_01290
MHAY: VK67_01295
MVR: X781_2210
MVE: X875_1830
APL: APL_1543(wecG)
APJ: APJL_1571(wecG)
APA: APP7_1605(wecG)
BTO: WQG_3560
BTRE: F542_18400
BTRH: F543_20280
BTRA: F544_3970
KKO: Kkor_0932
BCIB: IM45_421
LCH: Lcho_0634
RBS: RHODOSMS8_03375(wecG)
BLAS: BSY18_3070
PGI: PG_0119
PGN: PGN_0233
PDI: BDI_0042
PSAC: PSM36_0191
SPON: HME9304_01554(wecG)
 » show all
Taxonomy
Reference
1  [PMID:3275612]
  Authors
Barr K, Ward S, Meier-Dieter U, Mayer H, Rick PD.
  Title
Characterization of an Escherichia coli rff mutant defective in transfer of N-acetylmannosaminuronic acid (ManNAcA) from UDP-ManNAcA to a lipid-linked intermediate involved in enterobacterial common antigen synthesis.
  Journal
J Bacteriol 170:228-33 (1988)
DOI:10.1128/JB.170.1.228-233.1988
  Sequence
[eco:b3794]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.180
IUBMB Enzyme Nomenclature: 2.4.1.180
ExPASy - ENZYME nomenclature database: 2.4.1.180
BRENDA, the Enzyme Database: 2.4.1.180
CAS: 113478-30-1

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