KEGG   ENZYME: 2.4.1.219Help
Entry
EC 2.4.1.219                Enzyme                                 

Name
vomilenine glucosyltransferase;
UDPG:vomilenine 21-beta-D-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase
Reaction(IUBMB)
UDP-glucose + vomilenine = UDP + raucaffricine [RN:R05882]
Reaction(KEGG)
Substrate
UDP-glucose [CPD:C00029];
vomilenine [CPD:C01761]
Product
UDP [CPD:C00015];
raucaffricine [CPD:C02074]
Comment
The indole alkaloid raucaffricine accumulates during the culture of Rauvolfia cell suspensions.
History
EC 2.4.1.219 created 2002
Pathway
ec00901  Indole alkaloid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K12695  raucaffricine beta-D-glucosidase / vomilenine glucosyltransferase
Genes
SIND: 105161651
Taxonomy
Reference
1  [PMID:10234858]
  Authors
Warzecha H, Obitz P, Stockigt J.
  Title
Purification, partial amino acid sequence and structure of the product of raucaffricine-O-beta-D-glucosidase from plant cell cultures of Rauwolfia serpentina.
  Journal
Phytochemistry 50:1099-109 (1999)
DOI:10.1016/S0031-9422(98)00689-X
Reference
2  [PMID:10975500]
  Authors
Warzecha H, Gerasimenko I, Kutchan TM, Stockigt J.
  Title
Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis.
  Journal
Phytochemistry 54:657-66 (2000)
DOI:10.1016/S0031-9422(00)00175-8
  Sequence
Reference
3
  Authors
Ruyter, C.M. and Stockigt, J.
  Title
Enzymatic formation of raucaffricine, the major indole alkaloid of Rauwolfia serpentina cell-suspension cultures.
  Journal
Helv Chim Acta 74:1707-1712 (1991)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.219
IUBMB Enzyme Nomenclature: 2.4.1.219
ExPASy - ENZYME nomenclature database: 2.4.1.219
BRENDA, the Enzyme Database: 2.4.1.219

DBGET integrated database retrieval system