KEGG   ENZYME: 2.4.1.270Help
Entry
EC 2.4.1.270                Enzyme                                 

Name
mannosylglucosyl-3-phosphoglycerate synthase;
MggA
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
GDP-mannose:2-O-(alpha-D-glucosyl)-3-phospho-D-glycerate 2-O-alpha-D-mannosyltransferase
Reaction(IUBMB)
GDP-mannose + 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate = GDP + 2-O-[2-O-(alpha-D-mannopyranosyl)-alpha-D-glucopyranosyl]-3-phospho-D-glycerate [RN:R09667]
Reaction(KEGG)
Substrate
GDP-mannose [CPD:C00096];
2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate [CPD:C19791]
Product
GDP [CPD:C00035];
2-O-[2-O-(alpha-D-mannopyranosyl)-alpha-D-glucopyranosyl]-3-phospho-D-glycerate [CPD:C19793]
Comment
The enzyme is involved in synthesis of 2-[2-O-(alpha-D-mannopranosyl)-alpha-D-glucopyranosyl]-D-glycerate. Petrotoga miotherma and Petrotoga mobilis accumulate this compound in response to water stress imposed by salt.
History
EC 2.4.1.270 created 2011
Orthology
K21369  mannosylglucosyl-3-phosphoglycerate synthase
Genes
PMO: Pmob_1143
Taxonomy
Reference
1  [PMID:20061481]
  Authors
Fernandes C, Mendes V, Costa J, Empadinhas N, Jorge C, Lamosa P, Santos H, da Costa MS
  Title
Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis.
  Journal
J Bacteriol 192:1624-33 (2010)
DOI:10.1128/JB.01424-09
  Sequence
[pmo:Pmob_1143]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.270
IUBMB Enzyme Nomenclature: 2.4.1.270
ExPASy - ENZYME nomenclature database: 2.4.1.270
BRENDA, the Enzyme Database: 2.4.1.270

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