KEGG   ENZYME: 2.4.1.280Help
Entry
EC 2.4.1.280                Enzyme                                 

Name
N,N'-diacetylchitobiose phosphorylase;
chbP (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
N,N'-diacetylchitobiose:phosphate N-acetyl-D-glucosaminyltransferase
Reaction(IUBMB)
N,N'-diacetylchitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate [RN:R09942]
Reaction(KEGG)
Substrate
N,N'-diacetylchitobiose [CPD:C01674];
phosphate [CPD:C00009]
Product
N-acetyl-D-glucosamine [CPD:C00140];
N-acetyl-alpha-D-glucosamine 1-phosphate [CPD:C04501]
Comment
The enzyme is specific for N,N'-diacetylchitobiose and does not phosphorylate other N-acetylchitooligosaccharides, cellobiose, trehalose, lactose, maltose or sucrose.
History
EC 2.4.1.280 created 2012
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
Orthology
K18675  N,N'-diacetylchitobiose phosphorylase
Genes
PSHI: SAMEA2665130_0494
VCH: VC0612
VCF: IR04_08010
VCS: MS6_0430
VCE: Vch1786_I0020
VCQ: EN18_06010
VCJ: VCD_003797
VCI: O3Y_02850
VCO: VC0395_A0141
VCR: VC395_0629
VVU: VV1_1665
VVY: VV2742
VPA: VP2487
VPB: VPBB_2313
VAG: N646_1584
VSP: VS_2514
VNI: VIBNI_A2830(chbp)
VAN: VAA_00772
VAU: VANGNB10_cI0512c(chbP)
VSC: VSVS12_00701(chbP)
VTA: A1621(chbP)
VFI: VF_2147
VSA: VSAL_I2584(chbP)
AWD: AWOD_I_0448(chbP)
PPR: PBPRA0517(CEPA)
CPY: Cphy_3854
CSC: Csac_1090
ATE: Athe_0459
XCE: Xcel_1053
 » show all
Taxonomy
Reference
1  [PMID:10913116]
  Authors
Park JK, Keyhani NO, Roseman S
  Title
Chitin catabolism in the marine bacterium Vibrio furnissii. Identification, molecular cloning, and characterization of A N, N'-diacetylchitobiose phosphorylase.
  Journal
J Biol Chem 275:33077-83 (2000)
DOI:10.1074/jbc.M001042200
  Sequence
Reference
2  [PMID:13678418]
  Authors
Honda Y, Kitaoka M, Hayashi K
  Title
Reaction mechanism of chitobiose phosphorylase from Vibrio proteolyticus: identification of family 36 glycosyltransferase in Vibrio.
  Journal
Biochem J 377:225-32 (2004)
DOI:10.1042/BJ20031171
  Sequence
Reference
3  [PMID:15274915]
  Authors
Hidaka M, Honda Y, Kitaoka M, Nirasawa S, Hayashi K, Wakagi T, Shoun H, Fushinobu S
  Title
Chitobiose phosphorylase from Vibrio proteolyticus, a member of glycosyl transferase family 36, has a clan GH-L-like (alpha/alpha)(6) barrel fold.
  Journal
Structure 12:937-47 (2004)
DOI:10.1016/j.str.2004.03.027
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.280
IUBMB Enzyme Nomenclature: 2.4.1.280
ExPASy - ENZYME nomenclature database: 2.4.1.280
BRENDA, the Enzyme Database: 2.4.1.280

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