KEGG   ENZYME: 2.4.2.46Help
Entry
EC 2.4.2.46                 Enzyme                                 

Name
galactan 5-O-arabinofuranosyltransferase;
AftA;
Rv3792
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname
galactofuranan:trans,octacis-decaprenylphospho-beta-D-arabinofuranose 5-O-alpha-D-arabinofuranosyltransferase
Reaction(IUBMB)
Adds an alpha-D-arabinofuranosyl group from trans,octacis-decaprenylphospho-beta-D-arabinofuranose at the 5-O-position of the eighth, tenth and twelfth galactofuranose unit of the galactofuranan chain of [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
Comment
Isolated from Mycobacterium tuberculosis and Corynebacterium glutamicum. These arabinofuranosyl groups form the start of an arabinofuranan chain as part of the of the cell wall in mycobacteria.
History
EC 2.4.2.46 created 2012
Orthology
K13686  galactan 5-O-arabinofuranosyltransferase
Genes
MTU: Rv3792(aftA)
MTV: RVBD_3792
MTC: MT3899.1
MRA: MRA_3832
MTF: TBFG_13826
MTB: TBMG_03839
MTK: TBSG_03862
MTZ: TBXG_003809
MTG: MRGA327_23350
MTE: CCDC5079_3521
MTUR: CFBS_4021
MTD: UDA_3792
MTUB: MT7199_3861(aftA)
MTUE: J114_20250
MTUL: TBHG_03730
MTUT: HKBT1_4004
MTUU: HKBT2_4014
MBO: BQ2027_MB3821(afta)
MBB: BCG_3854
MBT: JTY_3856
MBX: BCGT_3653
MAF: MAF_38070
MMIC: RN08_4181
MLE: ML0107
MLB: MLBr00107
MPA: MAP_0233c
MAO: MAP4_3638
MAVI: RC58_18085
MAVU: RE97_18120
MAV: MAV_0230
MAVD: NF84_01095
MAVR: LA63_01125
MAVA: LA64_01135
MIT: OCO_02350
MIA: OCU_02410
MID: MIP_00565
MYO: OEM_02460
MIR: OCQ_02350
MUL: MUL_4971
MMC: Mmcs_5002
MKM: Mkms_5090
MJL: Mjls_5383
MMI: MMAR_5354
MMM: W7S_01155
MLI: MULP_05632(aftA)
MHAD: B586_03105
MSG: MSMEI_6218(aftA)
MVA: Mvan_5629
MGI: Mflv_1176
MPHL: MPHLCCUG_00213(aftA)
MVQ: MYVA_5558
MAB: MAB_0190c
MABB: MASS_0188
MABO: NF82_00955
MCHE: BB28_00980
MSTE: MSTE_00189
CGL: NCgl0185(Cgl0188)
CGB: cg0236
CGU: WA5_0185(AftA)
CGT: cgR_0267
CGM: cgp_0236
CGJ: AR0_01230
CEF: CE0162
CDI: DIP0160
CDP: CD241_0159(aftA)
CDH: CDB402_0127(aftA)
CDT: CDHC01_0160(aftA)
CDE: CDHC02_0166(aftA)
CDR: CDHC03_0132(aftA)
CDA: CDHC04_0120(aftA)
CDZ: CD31A_0163(aftA)
CDB: CDBH8_0163(aftA)
CDS: CDC7B_0119(aftA)
CDD: CDCE8392_0117(aftA)
CDW: CDPW8_0122(aftA)
CDV: CDVA01_0116(aftA)
CDIP: ERS451417_00127(aftA)
CJK: jk0086
CUR: cu0105
CUA: CU7111_0112(aftA)
CAR: cauri_0101(aftA)
CPU: cpfrc_00102(aftA)
CPL: Cp3995_0104(aftA)
CPG: Cp316_0114(aftA)
CPP: CpP54B96_0107(aftA)
CPK: Cp1002_0100(aftA)
CPQ: CpC231_0101(aftA)
CPX: CpI19_0102(aftA)
CPZ: CpPAT10_0100(aftA)
COR: Cp267_0111(aftA)
COP: Cp31_0115(aftA)
COD: Cp106_0103(aftA)
COS: Cp4202_0100(aftA)
COI: CpCIP5297_0111(aftA)
COE: Cp258_0114(aftA)
COU: Cp162_0107(aftA)
CPSE: CPTA_00629
CPSU: CPTB_00904
CPSF: CPTC_00566
CRD: CRES_0492(aftA)
CUL: CULC22_00147(aftA)
CUC: CULC809_00149(aftA)
CUE: CULC0102_0145(aftA)
CUN: Cul210932_0150(aftA)
CUS: CulFRC11_0145(aftA)
CUQ: Cul210931_0144(aftA)
CUZ: Cul05146_0150(aftA)
CUJ: CUL131002_0134c(aftA)
CVA: CVAR_2886(aftA)
CTER: A606_00780
COA: DR71_1172(aftA)
CSX: CSING_00465(aftA)
CMQ: B840_00765(aftA)
CKU: UL82_00345(aftA)
CCJ: UL81_00540(aftA)
CMV: CMUST_00570(aftA)
CEI: CEPID_00975(aftA)
CTED: CTEST_00720(aftA)
CDX: CDES_01085(aftA)
CSP: WM42_1263
CPHO: CPHO_00630
CGV: CGLAU_00435(aftA)
CAQU: CAQU_00415
CAMG: CAMM_01040
NFA: NFA_1950(aftA)
NFR: ERS450000_04043(aftA)
NSR: NS506_00804(aftA)
RER: RER_02330(aftA)
REY: O5Y_01175
ROP: ROP_39510(aftA)
REQ: REQ_02200
RHB: NY08_3924
RFA: A3L23_02040(aftA)
RHS: A3Q41_01323(aftA)
RHU: A3Q40_03631(aftA)
GBR: Gbro_0250
GPO: GPOL_c04350(aftA)
GOR: KTR9_0241
TPR: Tpau_4121
SRT: Srot_2818
MMAR: MODMU_4713
SEN: SACE_5810
PSEA: WY02_17060
PSEE: FRP1_25680
CAI: Caci_0996
 » show all
Taxonomy
Reference
1  [PMID:16595677]
  Authors
Alderwick LJ, Seidel M, Sahm H, Besra GS, Eggeling L
  Title
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis.
  Journal
J Biol Chem 281:15653-61 (2006)
DOI:10.1074/jbc.M600045200
  Sequence
[cgl:NCgl0185] [mtu:Rv3792]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.46
IUBMB Enzyme Nomenclature: 2.4.2.46
ExPASy - ENZYME nomenclature database: 2.4.2.46
BRENDA, the Enzyme Database: 2.4.2.46

DBGET integrated database retrieval system