KEGG   ENZYME: 2.4.2.47Help
Entry
EC 2.4.2.47                 Enzyme                                 

Name
arabinofuranan 3-O-arabinosyltransferase;
AftC
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
BRITE hierarchy
Sysname
alpha-(1->5)-arabinofuranan:trans,octacis-decaprenylphospho-beta-D-arabinofuranose 3-O-alpha-D-arabinofuranosyltransferase
Reaction(IUBMB)
Adds an alpha-D-arabinofuranosyl group from trans,octacis-decaprenylphospho-beta-D-arabinofuranose at the 3-O-position of an alpha-(1->5)-arabinofuranan chain attached to a beta-(1->5)-galactofuranan chain
Comment
Isolated from Mycobacterium smegmatis. Involved in the formation of the cell wall in mycobacteria.
History
EC 2.4.2.47 created 2012
Pathway
ec00571  Lipoarabinomannan (LAM) biosynthesis
ec00572  Arabinogalactan biosynthesis - Mycobacterium
Orthology
K16647  arabinofuranan 3-O-arabinosyltransferase
Genes
RHX: AMK02_CH03523
MTU: Rv2673(aftC)
MTV: RVBD_2673
MTC: MT2747
MRA: MRA_2701
MTF: TBFG_12688
MTB: TBMG_01300
MTK: TBSG_01311
MTZ: TBXG_001291
MTG: MRGA327_16415
MTUR: CFBS_2825
MTD: UDA_2673
MTUB: MT7199_2705(aftC)
MTUC: J113_18595
MTUE: J114_14270
MTUH: I917_18775
MTUL: TBHG_02609
MTUT: HKBT1_2816
MTUU: HKBT2_2819
MBO: BQ2027_MB2692(aftc)
MBB: BCG_2686
MBT: JTY_2680
MBX: BCGT_2505
MAF: MAF_26770
MMIC: RN08_2957
MLE: ML1338
MLB: MLBr01338
MPA: MAP_2793
MAO: MAP4_1019
MAVI: RC58_05015
MAVU: RE97_05010
MAV: MAV_3565
MIT: OCO_33990
MIA: OCU_34010
MID: MIP_05118
MYO: OEM_34370
MIR: OCQ_35210
MLP: MLM_1549
MUL: MUL_3307
MMC: Mmcs_2217
MKM: Mkms_2263
MJL: Mjls_2206
MMI: MMAR_2043
MMM: W7S_17000
MHAD: B586_14375
MVA: Mvan_2488
MGI: Mflv_3915
MVQ: MYVA_2378
MAB: MAB_2978
MABB: MASS_2913
MCHE: BB28_14985
MSTE: MSTE_02947
ASD: AS9A_1785
CGL: NCgl1822(Cgl1897)
CGB: cg2077
CGU: WA5_1822
CGT: cgR_1726
CGM: cgp_2077
CGJ: AR0_08925
CEF: CE1790
CDI: DIP1690
CDP: CD241_1623(aftC)
CDH: CDB402_1581(aftC)
CDT: CDHC01_1626(aftC)
CDE: CDHC02_1560(aftC)
CDR: CDHC03_1588(aftC)
CDA: CDHC04_1588(aftC)
CDZ: CD31A_1697(aftC)
CDB: CDBH8_1664(aftC)
CDS: CDC7B_1674(aftC)
CDD: CDCE8392_1586(aftC)
CDW: CDPW8_1682(aftC)
CDV: CDVA01_1550(aftC)
CDIP: ERS451417_01703(aftC)
CJK: jk1071
CUR: cu0918
CUA: CU7111_0904(aftC)
CAR: cauri_1439(aftC)
CPU: cpfrc_01195(aftC)
COP: Cp31_1204
CPSE: CPTA_01768
CPSU: CPTB_01995
CPSF: CPTC_01759
CRD: CRES_1163(aftC)
CUL: CULC22_01304(aftC)
CUC: CULC809_01290(aftC)
CUE: CULC0102_1419(aftC)
CVA: CVAR_1564(aftC)
CTER: A606_06205
CGY: CGLY_08085(aftC)
COA: DR71_2114
CKU: UL82_05965(aftC)
CSP: WM42_2540
CAMG: CAMM_06160
CMIN: NCTC10288_01062(aftC)
NFA: NFA_37340
NNO: NONO_c52550(aftC)
NSR: NS506_05834(aftC)
RER: RER_28550(aftC)
REY: O5Y_13155
ROP: ROP_68480(aftC)
REQ: REQ_20660
RHB: NY08_1194
RRT: 4535765_02099(aftC_1) 4535765_02476(aftC_2)
GBR: Gbro_2268
GOR: KTR9_2184
TPR: Tpau_1896
SRT: Srot_1649
SCO: SCO4733(SC6G4.11)
SCT: SCAT_3624
STRM: M444_20855
SLE: sle_29320(sle_29320)
STRD: NI25_15280
SALF: SMD44_05257(aftC)
SALJ: SMD11_4226(aftC)
SFK: KY5_4826
 » show all
Taxonomy
Reference
1  [PMID:18627460]
  Authors
Birch HL, Alderwick LJ, Bhatt A, Rittmann D, Krumbach K, Singh A, Bai Y, Lowary TL, Eggeling L, Besra GS
  Title
Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase.
  Journal
Mol Microbiol 69:1191-206 (2008)
DOI:10.1111/j.1365-2958.2008.06354.x
  Sequence
[cgl:NCgl1822] [msm:MSMEG_2785] [mtu:Rv2673]
Reference
2  [PMID:21595486]
  Authors
Zhang J, Angala SK, Pramanik PK, Li K, Crick DC, Liav A, Jozwiak A, Swiezewska E, Jackson M, Chatterjee D
  Title
Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors.
  Journal
ACS Chem Biol 6:819-28 (2011)
DOI:10.1021/cb200091m
  Sequence
[mtu:Rv2673]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.47
IUBMB Enzyme Nomenclature: 2.4.2.47
ExPASy - ENZYME nomenclature database: 2.4.2.47
BRENDA, the Enzyme Database: 2.4.2.47

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