KEGG   ENZYME: 2.5.1.26Help
Entry
EC 2.5.1.26                 Enzyme                                 

Name
alkylglycerone-phosphate synthase;
alkyldihydroxyacetonephosphate synthase;
alkyldihydroxyacetone phosphate synthetase;
alkyl DHAP synthetase;
alkyl-DHAP;
dihydroxyacetone-phosphate acyltransferase;
DHAP-AT
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase
Reaction(IUBMB)
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion [RN:R04311]
Reaction(KEGG)
Substrate
1-acyl-glycerone 3-phosphate [CPD:C03372];
long-chain alcohol [CPD:C00339]
Product
alkyl-glycerone 3-phosphate [CPD:C03715];
long-chain acid anion [CPD:C03129]
Comment
The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.
History
EC 2.5.1.26 created 1984
Pathway
ec00565  Ether lipid metabolism
ec01100  Metabolic pathways
Orthology
K00803  alkyldihydroxyacetonephosphate synthase
Genes
HSA: 8540(AGPS)
PTR: 740316(AGPS)
PPS: 100984427(AGPS)
GGO: 101149685(AGPS)
PON: 100431719(AGPS)
NLE: 100591232(AGPS)
MCC: 702139(AGPS)
MCF: 102140514(AGPS)
CSAB: 103217394(AGPS)
RRO: 104677409(AGPS)
RBB: 108527132(AGPS)
CJC: 100395942(AGPS)
SBQ: 101029189(AGPS)
MMU: 228061(Agps)
RNO: 84114(Agps)
CGE: 100756809(Agps)
NGI: 103751783(Agps)
HGL: 101699622(Agps)
OCU: 100353420(AGPS)
TUP: 102484610(AGPS)
CFA: 488421(AGPS)
AML: 100469531(AGPS)
UMR: 103659606(AGPS)
ORO: 101385391(AGPS)
FCA: 101094364(AGPS)
PTG: 102967317(AGPS)
AJU: 106988755(AGPS)
BTA: 613679(AGPS)
BOM: 102284431(AGPS)
BIU: 109566135(AGPS)
PHD: 102343608(AGPS)
CHX: 102176465(AGPS)
OAS: 101104553(AGPS)
SSC: 100627169(AGPS)
CFR: 102507465(AGPS)
CDK: 105098518(AGPS)
BACU: 103018985(AGPS)
LVE: 103071914(AGPS)
OOR: 101282710(AGPS)
ECB: 100053590(AGPS)
EPZ: 103561802 103566579(AGPS)
EAI: 106826616(AGPS)
MYB: 102258371(AGPS)
MYD: 102756569(AGPS)
HAI: 109388927(AGPS)
RSS: 109451252(AGPS)
PALE: 102892291(AGPS)
LAV: 100654852(AGPS)
TMU: 101355950
MDO: 100019424(AGPS)
SHR: 100919142(AGPS)
OAA: 100084919(AGPS)
GGA: 424135(AGPS)
MGP: 100548038(AGPS)
CJO: 107316651(AGPS)
APLA: 101803750(AGPS)
ACYG: 106030029(AGPS)
TGU: 100220704(AGPS)
GFR: 102036620(AGPS)
FAB: 101816574(AGPS)
PHI: 102108738(AGPS)
PMAJ: 107207510(AGPS)
CCAE: 111931723(AGPS)
CCW: 104693837(AGPS)
FPG: 101920772(AGPS)
FCH: 102054636(AGPS)
CLV: 102096766(AGPS)
EGZ: 104132708(AGPS)
AAM: 106499217(AGPS)
ASN: 102381502(AGPS)
AMJ: 102576146(AGPS)
PSS: 102454366(AGPS)
CMY: 102942743(AGPS)
CPIC: 101952600(AGPS)
ACS: 100560680(agps)
PVT: 110085775(AGPS)
PBI: 103048687(AGPS)
GJA: 107119833(AGPS)
XLA: 108703003(agps.S) 446408(agps.L)
XTR: 100145360(agps)
NPR: 108788331(AGPS)
DRE: 386801(agps)
SGH: 107561723 107600732(agps)
IPU: 108266713(agps)
AMEX: 103047643(agps)
TRU: 101062224(agps)
LCO: 104924426(agps)
NCC: 104965530(agps)
MZE: 101468014(agps)
OLA: 101163286(agps)
XMA: 102237026(agps)
PRET: 103458178(agps)
NFU: 107389988(agps)
KMR: 108239795(agps)
CSEM: 103391874(agps)
LCF: 108882981(agps)
SDU: 111218832(agps)
HCQ: 109507896(agps)
BPEC: 110166627(agps)
MALB: 109958065(agps)
ELS: 105016233(agps)
SFM: 108920255 108928045(agps)
LCM: 102349851(AGPS)
CMK: 103176581(agps)
CIN: 100175580
SPU: 585499(agps)
APLC: 110986604
SKO: 100373757
DME: Dmel_CG10253(ADPS)
DSI: Dsimw501_GD25643(Dsim_GD25643)
MDE: 101894938
AAG: 5573336
AME: 725343
BIM: 100749573
BTER: 100649138
SOC: 105192912
AEC: 105146748
ACEP: 105617550
PBAR: 105430375
HST: 105183131
DQU: 106749463
CFO: 105249762
LHU: 105677256
PGC: 109853595
PCF: 106785352
NVI: 100115142
MDL: 103579648
TCA: 658221
DPA: 109544565
NVL: 108561270
BMOR: 101738589
PMAC: 106713343
PRAP: 111000137
HAW: 110372057
PXY: 105380403
API: 100168099
DNX: 107173787
CLEC: 106670958
ZNE: 110826584
FCD: 110861331
TUT: 107367305
CEL: CELE_Y50D7A.7(ads-1)
CBR: CBG15716(Cbr-ads-1)
BMY: Bm1_07035
CRG: 105338951
MYI: 110456220
OBI: 106871118
EPA: 110244414
HMG: 100198088
AQU: 100632657
DDI: DDB_G0286183(agps)
DFA: DFA_09003(agps)
SMIN: v1.2.016915.t1(symbB.v1.2.016915.t1) v1.2.032495.t1(symbB.v1.2.032495.t1)
LMA: LMJF_30_0120(ADS1)
LIF: LINJ_30_0120(ADS1)
SPE: Spro_2461
SOD: Sant_0680
PAE: PA3026
PAEV: N297_3132
PAEI: N296_3132
PAEP: PA1S_10260
PAEM: U769_09800
PAEL: T223_10275
PAEG: AI22_23610
PAEC: M802_3129
PAEO: M801_2997
PMY: Pmen_1558
PMK: MDS_1621
PPSE: BN5_1367
PFL: PFL_2767
PPRO: PPC_2811
PKC: PKB_3801
PSOS: POS17_3284
PSET: THL1_2112
SSE: Ssed_0594
SHL: Shal_3330
SWD: Swoo_4359
MAQ: Maqu_1346
MHC: MARHY2046
MBS: MRBBS_1834(ads-1) MRBBS_1835
FBL: Fbal_2457
MVS: MVIS_4051
CBG: CbuG_0296
CBC: CbuK_0216
HCH: HCH_04625
ABO: ABO_1409
ADI: B5T_02340
APAC: S7S_09440
AXE: P40_11230
REH: H16_B1197(h16_B1197)
RME: Rmet_5443
BCJ: BCAM1106
BCEN: DM39_3909
BCEO: I35_4950
BMU: Bmul_4576
BCED: DM42_3986
BCON: NL30_07165
BPSL: WS57_08565
BFN: OI25_6219
RFR: Rfer_2332
POL: Bpro_5107
VEI: Veis_1876
DAC: Daci_1119
CBAA: SRAA_0701
DOL: Dole_2614
DAL: Dalk_3178
MXA: MXAN_1676
HOH: Hoch_3321
DBR: Deba_1505
PLA: Plav_1669
SHZ: shn_23425
OAN: Oant_2462
RPA: RPA1261
RPB: RPB_1270
RPT: Rpal_1454
OCA: OCAR_5302
MNO: Mnod_8219
PSF: PSE_1377
SMAZ: LH19_14210
CPY: Cphy_3390
TMR: Tmar_1765
MTU: Rv2251 Rv3107c(agpS)
MRA: MRA_2271 MRA_3139(agpS)
MTUR: CFBS_2384 CFBS_3277(agpS)
MTD: UDA_2250A UDA_3107c(agpS)
MTUC: J113_21680
MTUE: J114_16625
MTUH: I917_21820
MTUT: HKBT1_2375 HKBT1_3264(agpS)
MTUU: HKBT2_2377 HKBT2_3269(agpS)
MBB: BCG_2269 BCG_3132c(agpS)
MBT: JTY_2263 JTY_3127(agpS)
MAF: MAF_22620 MAF_31140(agpS)
MPA: MAP_2004
MAO: MAP4_1821
MAVI: RC58_09100
MAVU: RE97_09105
MAV: MAV_2186
MAVD: NF84_09850
MAVR: LA63_10050
MAVA: LA64_10075
MIT: OCO_21720
MIA: OCU_21900
MID: MIP_03067
MYO: OEM_19610
MIR: OCQ_20820
MLP: MLM_1915
MUL: MUL_1298
MMC: Mmcs_3374
MKM: Mkms_3436
MJL: Mjls_3385
MMI: MMAR_1525(agpS) MMAR_3344
MMM: W7S_10210
MHAD: B586_09870
MVA: Mvan_3761
MGI: Mflv_2772
MVQ: MYVA_3583
MAB: MAB_3884
MABB: MASS_3896
MABO: NF82_19450
MCHE: BB28_19895
MSTE: MSTE_04036
ASD: AS9A_1598
CRD: CRES_1995
CVA: CVAR_3057
CTER: A606_11350
CGY: CGLY_00595(agpS) CGLY_01220(adaS)
COA: DR71_437
NFA: NFA_13450
RER: RER_50150
REY: O5Y_23775
ROP: ROP_51520
REQ: REQ_19640
GBR: Gbro_4399
GOR: KTR9_4258
TPR: Tpau_1958
SCO: SCO0668(SCF91.28c)
SALB: XNR_5832
SGB: WQO_00705
SHY: SHJG_8313
SFI: SFUL_263
STRM: M444_27120
SPRI: SPRI_0349
SLE: sle_04430(sle_04430)
STRD: NI25_01930
SFK: KY5_0500
ARM: ART_2309
KRH: KRH_18610
BLIN: BLSMQ_0138
PFRE: RM25_1583
MPH: MLP_01180
NCA: Noca_4590
NDK: I601_1148
KFL: Kfla_0026
NDA: Ndas_0302
NAL: B005_3176
TCU: Tcur_1798
MMAR: MODMU_0264
KRA: Krad_1001
AMD: AMED_8417
AMN: RAM_43215
AMM: AMES_8287
AMZ: B737_8288
SESP: BN6_05790
ASE: ACPL_3761
AFS: AFR_33880
ACTS: ACWT_3633
TBI: Tbis_2238
HAU: Haur_0358
TTR: Tter_2454
TDE: TDE0138
TPED: TPE_0629
LIL: LA_2262
LIE: LIF_A1844
LIC: LIC_11674
LIS: LIL_11794
LBI: LEPBI_II0038(eapA)
LBF: LBF_4037
LST: LSS_12819
TTK: TST_0358
TLE: Tlet_1460
AFU: AF_0868
TGA: TGAM_1021
TSI: TSIB_0773
THE: GQS_01380
PPAC: PAP_08550
APE: APE_0308.1(eapA)
ACJ: ACAM_0229(eapA)
SSO: SSO1531
SOL: Ssol_2367
SSOA: SULA_2394
SSOL: SULB_2395
SSOF: SULC_2392
SAI: Saci_1188
POG: Pogu_2011
VMO: VMUT_1360
TPE: Tpen_1372
KCR: Kcr_0300
 » show all
Taxonomy
Reference
1  [PMID:7096336]
  Authors
Brown AJ, Snyder F.
  Title
Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism.
  Journal
J Biol Chem 257:8835-9 (1982)
Reference
2  [PMID:4401994]
  Authors
Wykle RL, Plantadosi C, Snyder F.
  Title
The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor.
  Journal
J Biol Chem 247:2944-8 (1972)
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.26
IUBMB Enzyme Nomenclature: 2.5.1.26
ExPASy - ENZYME nomenclature database: 2.5.1.26
BRENDA, the Enzyme Database: 2.5.1.26
CAS: 64060-42-0 102484-74-2

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