KEGG   ENZYME: 2.5.1.62Help
Entry
EC 2.5.1.62                 Enzyme                                 

Name
chlorophyll synthase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
chlorophyllide-a:phytyl-diphosphate phytyltransferase
Reaction(IUBMB)
chlorophyllide a + phytyl diphosphate = chlorophyll a + diphosphate [RN:R06284]
Reaction(KEGG)
R06284;
(other) R09067
Show
Substrate
chlorophyllide a [CPD:C02139];
phytyl diphosphate [CPD:C05427]
Product
chlorophyll a [CPD:C05306];
diphosphate [CPD:C00013]
Comment
Requires Mg2+. The enzyme is modified by binding of the first substrate, phytyl diphosphate, before reaction of the modified enzyme with the second substrate, chlorophyllide a, can occur. The reaction also occurs when phytyl diphosphate is replaced by geranylgeranyl diphosphate.
History
EC 2.5.1.62 created 2003
Pathway
ec00860  Porphyrin and chlorophyll metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K04040  chlorophyll/bacteriochlorophyll a synthase
Genes
ATH: AT3G51820(G4)
ALY: ARALYDRAFT_906533
CRB: 17887345
CSAT: 104711728 104781015 104791427
EUS: EUTSA_v10010408mg
BRP: 103832916 103841124 103842563 103848555 103848641 103869777
BNA: 106349059 106367679 106388176 106402842 106402855 106429833 106437912
BOE: 106311688 106315573
THJ: 104805975
CPAP: 110820892
CIT: 102615732
TCC: 18597511
GRA: 105780406
EGR: 104422084
VRA: 106758601
VAR: 108320403
CCAJ: 109815417
CAM: 101495080
LJA: Lj1g3v2372140.1(Lj1g3v2372140.1) Lj1g3v2372140.2(Lj1g3v2372140.2)
FVE: 101311975
PPER: 18774974
PMUM: 103341648
PAVI: 110768439
ZJU: 107430876
CSV: 101212175(CSCS)
CMO: 103502144
MCHA: 111013846
RCU: 8283148
JCU: 105648130
HBR: 110672569
VVI: 100250669
SLY: 101246752
SPEN: 107031547
SOT: 102580726
CANN: 107842693
NTA: 107781977(CHLG) 107794961(CHLG)
NSY: 104214712
NTO: 104101203
SIND: 105174586
HAN: 110865767
LSV: 111908627
BVG: 104892512
SOE: 110794882
OSA: 4338498
DOSA: Os05t0349700-01(Os05g0349700)
OBR: 102706758
BDI: 100841031
ATS: 109739353(LOC109739353)
SBI: 8061338
ZMA: 100274372
SITA: 101764766
PDA: 103709366
EGU: 105044579
MUS: 104000955
DCT: 110111644
ATR: 18433480
PPP: 112290402
CRE: CHLREDRAFT_5437(CHLG)
MNG: MNEG_2517
MIS: MICPUN_59614(CHLG)
MPP: MICPUCDRAFT_33362(CHLG)
APRO: F751_6816
SMIN: v1.2.019007.t1(symbB.v1.2.019007.t1)
FCY: FRACYDRAFT_223502(ChlG)
GTT: GUITHDRAFT_160205(CHLG)
HHA: Hhal_1600
LIM: L103DPR2_01006(cyoE)
LIH: L63ED372_00662(cyoE)
HYR: BSY239_1280(bchG)
RGE: RGE_33410(bchG)
METR: BSY238_2471(bchG)
SCL: sce0079(chlG)
AGC: BSY240_3642(bchG)
BRA: BRADO1634(bchG)
BBT: BBta_6422(bchG)
BRS: S23_19270(bchG)
AOL: S58_59030
BRO: BRAD285_5766(bchG)
RPA: RPA1530(bchG)
RPB: RPB_3992
RPC: RPC_1302
RPD: RPD_3747
RPE: RPE_1336
RPT: Rpal_1719
BOS: BSY19_4025(bchG)
MEX: Mext_4820
MEA: Mex_1p5277(bchG)
MDI: METDI5877(bchG)
MCH: Mchl_5287
MPO: Mpop_5365
MET: M446_3714
MOR: MOC_2257(chlG)
META: Y590_24630
MAQU: Maq22A_c01660(ubiA)
MSL: Msil_2061
RVA: Rvan_1002
BVR: BVIR_566
RSP: RSP_0279(bchG)
RCP: RCAP_rcc00671(bchG)
JAN: Jann_0165(bchG)
RDE: RD1_0144(bchG)
RLI: RLO149_p940670(bchG)
DSH: Dshi_3530(bchG)
PTP: RCA23_c29750(bchG)
RSU: NHU_00207(bchG)
RHC: RGUI_1990
LVS: LOKVESSMR4R_03328(ubiA)
SPHI: TS85_23025
SSAN: NX02_18315
BLAS: BSY18_2713(bchG)
AMV: ACMV_18920(bchG)
RRU: Rru_A0627
RRF: F11_03215
RCE: RC1_2078(bchG)
RPM: RSPPHO_00053(bchG)
HMO: HM1_0692(bchG)
SBH: SBI_03651
KFL: Kfla_6958
SYN: slr0056(chlG)
SYZ: MYO_123410(chlG)
SYY: SYNGTS_2317(chlG)
SYT: SYNGTI_2316(chlG)
SYS: SYNPCCN_2315(chlG)
SYQ: SYNPCCP_2315(chlG)
SYJ: D082_07670(chlG)
SYO: C7I86_12110(chlG)
SYW: SYNW1677(chlG)
SYC: syc2009_d(chlG)
SYG: sync_0696(chlG)
SYR: SynRCC307_0577(chlG)
SYX: SynWH7803_1776(chlG)
SYP: SYNPCC7002_A0548(chlG)
CYA: CYA_2138(chlG)
CYB: CYB_0533(chlG)
SYNR: KR49_13170
SYND: KR52_12905
SYH: Syncc8109_1904(chlG)
SYNW: SynWH8103_01908(chlG)
TEL: tll1539(chlG)
THN: NK55_04330(chlG)
CYI: CBM981_1481(chlG)
HHG: XM38_003210(chlG)
PMA: Pro_0424(chlG)
PMM: PMM0428(chlG)
PMT: PMT_0272
PMB: A9601_04831(chlG)
PMC: P9515_04901(chlG)
PMF: P9303_20661(chlG)
PMG: P9301_04521(chlG)
PMH: P9215_05071(chlG)
PMJ: P9211_04241(chlG)
PME: NATL1_04811(chlG)
PRC: EW14_0470
PRM: EW15_0511
AMR: AM1_1019(chlG)
MAR: MAE_22020(chlG)
MPK: VL20_3821
CYL: AA637_08970(chlG)
CYT: cce_4122(chlG)
TER: Tery_0876
ARP: NIES39_C02140(chlG)
GVI: gvip248(chlG)
GLJ: GKIL_1505(chlG)
ANA: all4480(chlG)
NOE: CLI64_12480(chlG)
AVA: Ava_3341
NAZ: Aazo_0020
ANB: ANA_C11932(chlG)
CALH: IJ00_11070
NSP: BMF81_03170(chlG)
CTHE: Chro_5252
STAN: STA3757_15840(chlG)
RCA: Rcas_3752
CTE: CT1270(chlG) CT1610(bchG)
 » show all
Taxonomy
Reference
1  [PMID:12530542]
  Authors
Schmid HC, Rassadina V, Oster U, Schoch S, Rudiger W.
  Title
Pre-loading of chlorophyll synthase with tetraprenyl diphosphate is an obligatory step in chlorophyll biosynthesis.
  Journal
Biol Chem 383:1769-78 (2002)
DOI:10.1515/BC.2002.198
  Sequence
Reference
2  [PMID:9092496]
  Authors
Oster U, Bauer CE, Rudiger W.
  Title
Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli.
  Journal
J Biol Chem 272:9671-6 (1997)
DOI:10.1074/jbc.272.15.9671
Reference
3  [PMID:7408876]
  Authors
Rudiger W, Benz J, Guthoff C.
  Title
Detection and partial characterization of activity of chlorophyll synthetase in etioplast membranes.
  Journal
Eur J Biochem 109:193-200 (1980)
DOI:10.1111/j.1432-1033.1980.tb04784.x
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.62
IUBMB Enzyme Nomenclature: 2.5.1.62
ExPASy - ENZYME nomenclature database: 2.5.1.62
BRENDA, the Enzyme Database: 2.5.1.62
CAS: 9077-08-1

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