KEGG   ENZYME: 2.5.1.79Help
Entry
EC 2.5.1.79                 Enzyme                                 

Name
thermospermine synthase;
TSPMS;
ACL5;
SAC51;
S-adenosyl 3-(methylthio)propylamine:spermidine 3-aminopropyltransferase (thermospermine synthesizing)
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
S-adenosyl 3-(methylsulfanyl)propylamine:spermidine 3-aminopropyltransferase (thermospermine forming)
Reaction(IUBMB)
S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+ [RN:R09531]
Reaction(KEGG)
Substrate
S-adenosyl 3-(methylsulfanyl)propylamine [CPD:C01137];
spermidine [CPD:C00315]
Product
S-methyl-5'-thioadenosine [CPD:C00170];
thermospermine [CPD:C19669];
H+ [CPD:C00080]
Comment
This plant enzyme is crucial for the proper functioning of xylem vessel elements in the vascular tissues of plants [3].
History
EC 2.5.1.79 created 2010, modified 2013
Orthology
K18787  thermospermine synthase
Genes
RSS: 109442319
ATH: AT5G19530(ACL5)
ALY: ARALYDRAFT_909990
CRB: 17882428 17889563
CSAT: 104703138 104706283 104714077 104736021 104770319
EUS: EUTSA_v10002037mg EUTSA_v10013833mg
BRP: 103845743 103851278
BNA: 106367869 106371801 106379211 106380754 106425813 106425814
BOE: 106315154 106321129 106322697
THJ: 104811216
GRA: 105773375
LJA: Lj5g3v0465980.1(Lj5g3v0465980.1) Lj5g3v2046170.1(Lj5g3v2046170.1)
SOE: 110795108
OSA: 4328835
DOSA: Os02t0237100-01(Os02g0237100)
OBR: 102706354
BDI: 100829809
ATS: 109775813(LOC109775813)
SBI: 8062753
CRE: CHLREDRAFT_206069(SPS1)
MNG: MNEG_7203
OLU: OSTLU_40897(SPD2)
FCY: FRACYDRAFT_206948(Fc_206948)
AAF: AURANDRAFT_31657(SPS1)
 » show all
Taxonomy
Reference
1  [PMID:19075322]
  Authors
Romer P, Faltermeier A, Mertins V, Gedrange T, Mai R, Proff P
  Title
Investigations about N-aminopropyl transferases probably involved in biomineralization.
  Journal
J Physiol Pharmacol 59 Suppl 5:27-37 (2008)
Reference
2  [PMID:17560575]
  Authors
Knott JM, Romer P, Sumper M
  Title
Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine.
  Journal
FEBS Lett 581:3081-6 (2007)
DOI:10.1016/j.febslet.2007.05.074
  Sequence
[ath:AT5G19530]
Reference
3  [PMID:18599510]
  Authors
Muniz L, Minguet EG, Singh SK, Pesquet E, Vera-Sirera F, Moreau-Courtois CL, Carbonell J, Blazquez MA, Tuominen H
  Title
ACAULIS5 controls Arabidopsis xylem specification through the prevention of premature cell death.
  Journal
Development 135:2573-82 (2008)
DOI:10.1242/dev.019349
  Sequence
[ath:AT5G19530]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.79
IUBMB Enzyme Nomenclature: 2.5.1.79
ExPASy - ENZYME nomenclature database: 2.5.1.79
BRENDA, the Enzyme Database: 2.5.1.79

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