KEGG   ENZYME: 2.5.1.97Help
Entry
EC 2.5.1.97                 Enzyme                                 

Name
pseudaminic acid synthase;
PseI;
NeuB3
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
phosphoenolpyruvate:2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose transferase (phosphate-hydrolysing, 2,7-acetylamino-transfering, 2-carboxy-2-oxoethyl-forming)
Reaction(IUBMB)
phosphoenolpyruvate + 2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose + H2O = 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid + phosphate [RN:R09841]
Reaction(KEGG)
Substrate
phosphoenolpyruvate [CPD:C00074];
2,4-bis(acetylamino)-2,4,6-trideoxy-beta-L-altropyranose;
H2O [CPD:C00001]
Product
5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid [CPD:C20082];
phosphate [CPD:C00009]
Comment
The enzyme requires a divalent metal ion, the highest activity values are observed in the presence of Mn2+ and Co2+ (10 mM).
History
EC 2.5.1.97 created 2011
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
Orthology
K15898  pseudaminic acid synthase
Genes
SJA: SJ2017_2979
AMG: AMEC673_04890
FPZ: LA55_1639(pseI)
FNA: OOM_1616
FNL: M973_06990
FPER: ACH24_00845
FGU: SD28_06730
ACAV: VI35_07445(pseI)
AEA: C2U39_08085(pseI)
ARV: C7N77_17160(pseI)
PSE: NH8B_3550
HPY: HP0178
HPJ: jhp_0166(neuB)
HPG: HPG27_163
HPB: HELPY_0182(neuB)
HPL: HPB8_1388(neuB)
HPO: HMPREF4655_20420(pseI)
HPQ: hp2017_0183(neuB)
HEF: HPF16_0186(neuB)
HPF: HPF30_1116(neuB)
HEQ: HPF32_0188(neuB)
HEX: HPF57_0197(neuB)
HPZ: HPKB_0188
HPX: HMPREF0462_0233(pseI)
HPYS: HPSA20_0199(pseI)
HPD: KHP_0177(neuB)
HEY: MWE_0252
HPYO: HPOK113_0186(neuB)
HPYL: HPOK310_0184(neuB)
HPYR: K747_09550
HPYI: K750_07650
HPYU: K751_06745
HPYM: K749_04795
HEB: U063_0520
HEZ: U064_0521
HHE: HH_0908
HAC: Hac_0364
HMS: HMU11700(neuB3)
HFE: HFELIS_15210(neuB3)
HCE: HCW_03725
HCM: HCD_03040
HCP: HCN_1783
HAD: CDV25_07195(pseI)
WSU: WS2109
SUA: Saut_0136
SULR: B649_00690
CJE: Cj1317(pseI)
CJB: BN148_1317(pseI)
CJJ: CJJ81176_1334(neuB)
CJU: C8J_1251(neuB)
CJI: CJSA_1255(pseI)
CJM: CJM1_1290(pseI)
CJS: CJS3_1417
CJEJ: N564_01335
CJEU: N565_01374
CJEN: N755_01370
CJEI: N135_01406
CJER: H730_07535
CJV: MTVDSCj20_1313(pseI)
CJY: QZ67_01452(pseI)
CJQ: UC78_1266(pseI)
CJR: CJE1512(neuB)
CFT: CFF04554_1565(pseI)
CFV: CFVI03293_1587(pseI)
CFX: CFV97608_1689(pseI)
CFZ: CSG_16920
CAMP: CFT03427_1513(pseI)
CCV: CCV52592_0565(pseI)
CLA: Cla_0169(pseI)
CLR: UPTC16701_0178(pseI)
CLM: UPTC16712_0176(pseI)
CLQ: UPTC4110_0170(pseI)
CLN: UPTC3659_0189(pseI)
CLL: CONCH_0164(pseI)
CCQ: N149_1280
CCF: YSQ_02260
CCY: YSS_07155
CCOI: YSU_02275
CCOF: VC76_06635(pseI)
CCOO: ATE51_00930(pseI)
CAJ: CIG1485E_1505(pseI)
CIS: CINS_0157(pseI)
CVO: CVOL_0160(pseI)
CPEL: CPEL_0174(pseI)
CAMR: CAQ16704_0169(pseI)
CSM: CSUB8521_0179(pseI)
CSF: CSUB8523_0173(pseI)
CHYO: CHH_1600(pseI)
CHV: CHELV3228_0385(pseI)
CPIN: CPIN18020_0127(pseI)
CCUN: CCUN_1340(pseI)
CLX: CLAN_1240(pseI)
CAVI: CAV_1218(pseI)
CHW: A2J15_000480(pseI)
ABU: Abu_2246(neuB)
ABT: ABED_2056
ABL: A7H1H_2193(pseI)
SDL: Sdel_2213
SMUL: SMUL_3176(pseI)
SHAL: SHALO_2912
SULJ: SJPD1_2797
NAM: NAMH_1595
DSF: UWK_02421
JEO: JMA_28170
CAC: CA_C2187(spsE)
CAE: SMB_G2220
CAY: CEA_G2201(spsE)
CBO: CBO2720
CBA: CLB_2661
CBH: CLC_2594
CBY: CLM_3086(pseI)
CBL: CLK_2105
CBK: CLL_A0832
CBI: CLJ_B2947
CBT: CLH_0798
CBE: Cbei_4278
CBZ: Cbs_4278
CBEI: LF65_04801
CSR: Cspa_c45320(pseI)
CSB: CLSA_c39500(pseI)
CLT: CM240_1654(pseI)
CSQ: CSCA_3176
CLD: CLSPO_c27820(pseI)
CTAE: BGI42_03935(pseI)
AOE: Clos_2510
CTH: Cthe_2229
HSC: HVS_04485(pseI2)
BHU: bhn_I2423
BHF: C3V43_13585(pseI)
PARC: CI960_11570(pseI)
PSAC: PSM36_1392(pseI)
PGS: CPT03_16765(pseI)
EST: DN752_19920(pseI)
PSEZ: HME7025_02498(pseI) HME7025_02499(neuB)
FLM: MY04_2866(neuB)
GFO: GFO_2016(NeuB)
FIN: KQS_04780(neuB)
DOD: DCS32_13465(pseI)
WIN: WPG_0822
TMAR: MARIT_1555(pseI)
TAJ: C1A40_06900(pseI)
FBU: UJ101_00315(neuB)
FLU: CHH17_13955(pseI)
MRO: MROS_1160
HTH: HTH_1538(neuB)
MSI: Msm_1539
MCUB: MCBB_1285(pseI)
MPY: Mpsy_2359
 » show all
Taxonomy
Reference
1  [PMID:16120604]
  Authors
Chou WK, Dick S, Wakarchuk WW, Tanner ME
  Title
Identification and characterization of NeuB3 from Campylobacter jejuni as a pseudaminic acid synthase.
  Journal
J Biol Chem 280:35922-8 (2005)
DOI:10.1074/jbc.M507483200
  Sequence
[cje:Cj1317]
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.97
IUBMB Enzyme Nomenclature: 2.5.1.97
ExPASy - ENZYME nomenclature database: 2.5.1.97
BRENDA, the Enzyme Database: 2.5.1.97

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