KEGG   ENZYME: 2.6.1.36Help
Entry
EC 2.6.1.36                 Enzyme                                 

Name
L-lysine 6-transaminase;
lysine 6-aminotransferase;
lysine epsilon-aminotransferase;
lysine epsilon-transaminase;
lysine:2-ketoglutarate 6-aminotransferase;
L-lysine-alpha-ketoglutarate aminotransferase;
L-lysine-alpha-ketoglutarate 6-aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-lysine:2-oxoglutarate 6-aminotransferase
Reaction(IUBMB)
L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate [RN:R00457]
Reaction(KEGG)
Substrate
L-lysine [CPD:C00047];
2-oxoglutarate [CPD:C00026]
Product
(S)-2-amino-6-oxohexanoate [CPD:C04076];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein. The product (L-allysine) is converted into the intramolecularly dehydrated form, (S)-2,3,4,5-tetrahydropyridine-2-carboxylate.
History
EC 2.6.1.36 created 1972, modified 2011
Orthology
K03918  L-lysine 6-transaminase
Genes
PCA: Pcar_2442
PACE: A6070_03115
PEF: A7E78_13695
DPS: DP2333
LLU: AKJ09_00862 AKJ09_07223
BMX: BMS_1868
AEX: Astex_2700
MTU: Rv3290c(lat)
MTV: RVBD_3290c
MTC: MT3389(lat)
MRA: MRA_3331(lat)
MTUR: CFBS_3481(lat)
MTO: MTCTRI2_3357(lat)
MTD: UDA_3290c(lat)
MTN: ERDMAN_3606(lat)
MTUC: J113_22960
MTUE: J114_17640
MTUH: I917_23125
MTUL: TBHG_03226
MTUT: HKBT1_3468(lat)
MTUU: HKBT2_3475(lat)
MTQ: HKBS1_3478(lat)
MBO: BQ2027_MB3318C(lat)
MBB: BCG_3319c(lat) BCG_3354c(lat')
MBT: JTY_3315(lat)
MBM: BCGMEX_3317c(lat) BCGMEX_3352c(lat')
MAF: MAF_33010(lat)
MMIC: RN08_3630
MCE: MCAN_33131(lat)
MCQ: BN44_70081(lat)
MCV: BN43_60305(lat)
MCX: BN42_41348(lat)
MCZ: BN45_60328(lat)
MPA: MAP_3410c(lat)
MAO: MAP4_0371
MAVI: RC58_01770
MAVU: RE97_01780
MAV: MAV_4262
MIT: OCO_41280
MIA: OCU_41200
MID: MIP_06217
MYO: OEM_41540
MIR: OCQ_42550
MLP: MLM_3421
MUL: MUL_2644(lat)
MMC: Mmcs_1272
MKM: Mkms_1289
MJL: Mjls_1301
MMI: MMAR_1243(lat)
MMAE: MMARE11_12110(lat)
MMM: W7S_20600
MLI: MULP_01403(lat)
MHAD: B586_17690
MSG: MSMEI_1721(lat)
MVA: Mvan_1652
MGI: Mflv_4796
MPHL: MPHLCCUG_01571(lat)
MVQ: MYVA_1409
MAB: MAB_3646c
MABB: MASS_3658
MCHE: BB28_18635
MSTE: MSTE_03793
ASD: AS9A_4565
NFA: NFA_9840
NFR: ERS450000_03131(lat)
NCY: NOCYR_1048(lat)
RHA: RHA1_ro06277(lat)
RER: RER_21100(lat)
REY: O5Y_10070
ROP: ROP_63400(lat)
REQ: REQ_33980
RHB: NY08_3760
RFA: A3L23_01897(lat)
RHS: A3Q41_01468(lat)
RHU: A3Q40_03707(lat)
RRT: 4535765_03390(lat)
SRT: Srot_1934
SCT: SCAT_5685(lat)
STRD: NI25_03825
SLAU: SLA_6893
MPH: MLP_13250(lat)
SRO: Sros_7678
FAL: FRAAL4414(lat)
SEN: SACE_0784(lat)
ACTI: UA75_11255
ACAD: UA74_11170
AHG: AHOG_10515(lat)
TBI: Tbis_2682
STI: Sthe_2786
TTR: Tter_1717
TAI: Taci_1141
TLI: Tlie_0683
SRU: SRU_0799
SRM: SRM_00977(argD)
RMR: Rmar_2194
PHE: Phep_1211
SMIZ: 4412673_03435(lat)
MUC: MuYL_1402
MGOT: MgSA37_01318(lat)
EAO: BD94_2101
ELB: VO54_00617(lat)
CHZ: CHSO_2425(lat)
CTAK: 4412677_00654(lat)
FBA: FIC_01043
IAL: IALB_1476(lat)
MRO: MROS_2755
ABI: Aboo_0464
 » show all
Taxonomy
Reference
1  [PMID:5722275]
  Authors
Soda K, Misono H, Yamamoto T.
  Title
L-Lysine:alpha-ketoglutarate aminotransferase. I. Identification of a product, delta-1-piperideine-6-carboxylic acid.
  Journal
Biochemistry 7:4102-9 (1968)
Reference
2  [PMID:5722276]
  Authors
Soda K, Misono H.
  Title
L-Lysine:alpha-ketoglutarate aminotransferase. II. Purification, crystallization, and properties.
  Journal
Biochemistry 7:4110-9 (1968)
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.36
IUBMB Enzyme Nomenclature: 2.6.1.36
ExPASy - ENZYME nomenclature database: 2.6.1.36
BRENDA, the Enzyme Database: 2.6.1.36
CAS: 9054-68-6

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