KEGG   ENZYME: 2.6.1.49Help
Entry
EC 2.6.1.49                 Enzyme                                 

Name
dihydroxyphenylalanine transaminase;
dopa transaminase;
dihydroxyphenylalanine aminotransferase;
aspartate-DOPP transaminase (ADT);
L-dopa transaminase;
dopa aminotransferase;
glutamate-DOPP transaminase (GDT);
phenylalanine-DOPP transaminase (PDT);
DOPA 2-oxoglutarate aminotransferase;
DOPAATS
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase
Reaction(IUBMB)
L-dopa + 2-oxoglutarate = 3,4-dihydroxyphenylpyruvate + L-glutamate [RN:R02077]
Reaction(KEGG)
Substrate
L-dopa [CPD:C00355];
2-oxoglutarate [CPD:C00026]
Product
3,4-dihydroxyphenylpyruvate [CPD:C04045];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.49 created 1972
Pathway
ec00350  Tyrosine metabolism
Reference
1  [PMID:5829872]
  Authors
Fonnum F, Larsen K.
  Title
Purification and properties of dihydroxyphenylalanine transaminase from guinea pig brain.
  Journal
J Neurochem 12:589-98 (1965)
DOI:10.1111/j.1471-4159.1965.tb04251.x
Reference
2  [PMID:17616348]
  Authors
Ranjith NK, Sasikala Ch, Ramana ChV.
  Title
Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine.
  Journal
Res Microbiol 158:506-11 (2007)
DOI:10.1016/j.resmic.2007.04.008
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.49
IUBMB Enzyme Nomenclature: 2.6.1.49
ExPASy - ENZYME nomenclature database: 2.6.1.49
BRENDA, the Enzyme Database: 2.6.1.49
CAS: 37277-98-8

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