KEGG   ENZYME: 2.7.1.77Help
Entry
EC 2.7.1.77                 Enzyme                                 

Name
nucleoside phosphotransferase;
nonspecific nucleoside phosphotransferase;
nucleotide:3'-deoxynucleoside 5'-phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
nucleotide:nucleoside 5'-phosphotransferase
Reaction(IUBMB)
a nucleotide + a 2'-deoxyribonucleoside = a nucleoside + a 2'-deoxyribonucleoside 5'-phosphate [RN:R07341]
Reaction(KEGG)
Substrate
nucleotide [CPD:C00215];
2'-deoxyribonucleoside [CPD:C02269]
Product
nucleoside [CPD:C00801];
2'-deoxyribonucleoside 5'-phosphate [CPD:C00676]
Comment
Phenyl phosphate and nucleoside 3'-phosphates can act as donors, although not so well as nucleoside 5'-phosphates. Nucleosides as well as 2'-deoxyribonucleosides can act as acceptors.
History
EC 2.7.1.77 created 1972
Reference
1  [PMID:6061424]
  Authors
Brunngraber EF, Chargaff E.
  Title
Purification and properties of a nucleoside phosphotransferase from carrot.
  Journal
J Biol Chem 242:4834-40 (1967)
Reference
2  [PMID:6279651]
  Authors
Prasher DC, Carr MC, Ives DH, Tsai TC, Frey PA.
  Title
Nucleoside phosphotransferase from barley. Characterization and evidence for ping pong kinetics involving phosphoryl enzyme.
  Journal
J Biol Chem 257:4931-9 (1982)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.77
IUBMB Enzyme Nomenclature: 2.7.1.77
ExPASy - ENZYME nomenclature database: 2.7.1.77
BRENDA, the Enzyme Database: 2.7.1.77
CAS: 9055-37-2

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